Aliskiren C₃₀H₅₃N₃O₆

Active ingredient description

Aliskiren is an orally active, non-peptide, potent and selective direct inhibitor of human renin. By inhibiting the enzyme renin, aliskiren inhibits the RAAS at the point of activation, blocking the conversion of angiotensinogen to angiotensin I and decreasing levels of angiotensin I and angiotensin II.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Aliskiren
C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09X Other agents acting on the renin-angiotensin system → C09XA Renin-inhibitors
Discover more medicines within C09XA02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
European Medicines Agency (EU)
Summary of Product Characteristics (SPC)
FDA, National Drug Code (US)
Structured Product Labeling (SPL/PLR)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₃₀H₅₃N₃O₆
Molecular mass: 551.758 g/mol

External identifiers

CAS Substance: 173334-57-1
DrugBank Drug: DB09026
KEGG Drug: D03208
PubChem Compound: 5493444
RxNorm Ingredient: 325646
SNOMED-CT Concept: 426725002
Aliskiren (substance)
UNII Identifier: 502FWN4Q32
ALISKIREN

Medicines

Aliskiren is an active ingredient of these brands:

United States (US)

Austria (AT)

Canada (CA)

  • RASILEZ as ALISKIREN HEMIFUMARATE

Cyprus (CY)

Estonia (EE)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

  • RASILEZ as ALISKIREN HEMIFUMARATE

Lithuania (LT)

Mexico (MX)

Netherlands (NL)

Poland (PL)

Romania (RO)

South Africa (ZA)

Spain (ES)

United Kingdom (UK)

  • RASILEZ as ALISKIREN HEMIFUMARATE

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

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