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Aliskiren

Description

Aliskiren is an orally active, non-peptide, potent and selective direct inhibitor of human renin. By inhibiting the enzyme renin, aliskiren inhibits the RAAS at the point of activation, blocking the conversion of angiotensinogen to angiotensin I and decreasing levels of angiotensin I and angiotensin II.

ATC Classification

Code
Title
Category
C09XA02
Aliskiren
C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09X Other agents acting on the renin-angiotensin system → C09XA Renin-inhibitors

Trade names

Trade name
Countries

United States

Austria Canada Cyprus Netherlands Spain

United States

Trade names (in combination): RASILEZ HCT TEKTURNA HCT

Product Monographs

Monograph
Type
Country
RASILEZ Film-coated tablet
MPI, EU: SmPC