Amfepramone Other names: Diethylpropion

Chemical formula: C₁₃H₁₉NO  Molecular mass: 205.296 g/mol  PubChem compound: 7029

Active ingredient description

Amfepramone is a sympathomimetic amine with some pharmacologic activity similar to that of the prototype drugs of this class used in obesity, the amphetamines. Actions include some central nervous system stimulation and elevation of blood pressure. It has not been established, however, that the action of such drugs in treating obesity is primarily one of appetite suppression. For example, other central nervous system actions or metabolic effects may be involved.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A08AA03 Amfepramone A Alimentary tract and metabolism → A08 Antiobesity preparations, excl. diet products → A08A Antiobesity preparations, excl. diet products → A08AA Centrally acting antiobesity products
Discover more medicines within A08AA03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DIETHYLPROPION HYDROCHLORIDE ER Extended-release tablet FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 90-84-6
DrugBank Drug: DB00937
KEGG Drug: D07444
PubChem Compound: 7029
RxNorm Ingredient: 3389
SNOMED-CT Concept: 387303009
Amfepramone (substance)
UNII Identifier: Q94YYU22B8


Amfepramone is an active ingredient of these brands:

Hong Kong (HK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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