Chemical formula: C₅H₇N₃  Molecular mass: 109.132 g/mol  PubChem compound: 5918

Therapeutic indications

Amifampridine is indicated for:

Lambert-Eaton myasthenic syndrome (LEMS)

Population group: only adults (18 years old or older)

Symptomatic treatment of Lambert-Eaton myasthenic syndrome (LEMS) in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):


Amifampridine is contraindicated in the following cases:



Uncontrolled asthma

Airway hyperreactivity



Medicinal products that can prolong QTc interval

Drugs prolonging QT interval

Congenital QT syndrome

Congenital long QT syndrome

Medicinal products with a narrow therapeutic window

Narrow Therapeutic Index Drugs (NTI)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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