Amiloride

Active ingredient description

Amiloride has mild diuretic and anti-hypertensive activity. It acts primarily in the distal tubule and does not require aldosterone for its action. Amiloride is a mild natriuretic which does not initiate a concomitant decrease in potassium levels.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Amiloride
C Cardiovascular system → C03 Diuretics → C03D Potassium-sparing agents → C03DB Other potassium-sparing agents
Discover more medicines within C03DB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Medicines

Amiloride is the active ingredient of these drugs:

Drug
Countries

Cyprus

Canada

France

Amiloride is also found within below combination drugs:

ACUMOD , AMERIDE , AMILORETIC , AMILOSTAD HCT , AMILZIDE , AMITHIAZIDE , AMITRID , AMURETIC , ANCLORIC , BETARETIC , BILDURETIC , DEZRETIC , DIUPRESS , DIURAMIN , DIUZINE , FRUMIL , KALTEN , LOGIRENE , LORETIC , MILOREX , MODUCREN , MODUCRIN , MODURETIC , NOVAMILOR , SERVATRIN , TENSOFLUX , TIALORID , VERICORDIN COMPUESTO

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₆H₈ClN₇O
Molecular mass: 229.627 g/mol

External identifiers

CAS Substance: 2016-88-8
CAS Substance: 2609-46-3
DrugBank Drug: DB00594
KEGG Drug: D07447
PubChem Compound: 16231
RxNorm Ingredient: 644
SNOMED-CT Concept: 387503008
Amiloride (substance)
UNII Identifier: 7DZO8EB0Z3
AMILORIDE