Chemical formula: C₆H₈ClN₇O Molecular mass: 229.627 g/mol PubChem compound: 16231
Amiloride has mild diuretic and anti-hypertensive activity. It acts primarily in the distal tubule and does not require aldosterone for its action. Amiloride is a mild natriuretic which does not initiate a concomitant decrease in potassium levels.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
|C Cardiovascular system → C03 Diuretics → C03D Potassium-sparing agents → C03DB Other potassium-sparing agents
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
|AMILORIDE ROSEMONT Oral solution
|Medicines & Healthcare Products Regulatory Agency (GB)
|MPI, EU: SmPC
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