Amiloride

Active ingredient description

Amiloride has mild diuretic and anti-hypertensive activity. It acts primarily in the distal tubule and does not require aldosterone for its action. Amiloride is a mild natriuretic which does not initiate a concomitant decrease in potassium levels.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
C03DB01
Amiloride
C Cardiovascular system → C03 Diuretics → C03D Potassium-sparing agents → C03DB Other potassium-sparing agents
Discover more medicines within C03DB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
AMILORIDE ROSEMONT Oral solution
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₆H₈ClN₇O
Molecular mass: 229.627 g/mol

External identifiers

CAS Substance: 2016-88-8
CAS Substance: 2609-46-3
DrugBank Drug: DB00594
KEGG Drug: D07447
PubChem Compound: 16231
RxNorm Ingredient: 644
SNOMED-CT Concept: 387503008
Amiloride (substance)
UNII Identifier: 7DZO8EB0Z3
AMILORIDE

Medicines

Amiloride is an active ingredient of these brands:

Australia (AU)

  • (combination) MODURETIC as AMILORIDE HYDROCHLORIDE

Austria (AT)

Brazil (BR)

  • (combination) ANCLORIC as AMILORIDE HYDROCHLORIDE
  • (combination) DIUPRESS as AMILORIDE HYDROCHLORIDE
  • (combination) MODURETIC as AMILORIDE HYDROCHLORIDE

Canada (CA)

  • MIDAMOR as AMILORIDE HYDROCHLORIDE
  • (combination) AMILZIDE as AMILORIDE HYDROCHLORIDE
  • (combination) NOVAMILOR as AMILORIDE HYDROCHLORIDE

Cyprus (CY)

  • ALVERIX
  • (combination) FRUMIL as AMILORIDE HYDROCHLORIDE ANHYDROUS
  • (combination) MILOREX as AMILORIDE HYDROCHLORIDE

Ecuador (EC)

Estonia (EE)

  • (combination) MODURETIC as AMILORIDE HYDROCHLORIDE

Finland (FI)

  • (combination) AMITRID as AMILORIDE HYDROCHLORIDE
  • (combination) DIURAMIN as AMILORIDE HYDROCHLORIDE

France (FR)

  • MODAMIDE as AMILORIDE HYDROCHLORIDE
  • (combination) LOGIRENE as AMILORIDE HYDROCHLORIDE
  • (combination) MODUCREN as AMILORIDE HYDROCHLORIDE

Germany (DE)

  • (combination) MODUCREN as AMILORIDE HYDROCHLORIDE
  • (combination) MODUCRIN as AMILORIDE HYDROCHLORIDE
  • (combination) TENSOFLUX as AMILORIDE HYDROCHLORIDE

Hong Kong (HK)

  • (combination) AMITHIAZIDE as AMILORIDE HYDROCHLORIDE
  • (combination) BILDURETIC as AMILORIDE HYDROCHLORIDE

Ireland (IE)

  • (combination) FRUMIL as AMILORIDE HYDROCHLORIDE ANHYDROUS

Malta (MT)

  • (combination) MILOREX as AMILORIDE HYDROCHLORIDE

Mexico (MX)

  • (combination) MODURETIC as AMILORIDE HYDROCHLORIDE

New Zealand (NZ)

  • (combination) FRUMIL as AMILORIDE HYDROCHLORIDE ANHYDROUS
  • (combination) MODURETIC as AMILORIDE HYDROCHLORIDE

Nigeria (NG)

  • (combination) LEMURETIC as AMILORIDE HYDROCHLORIDE
  • (combination) ZORETIC as AMILORIDE HYDROCHLORIDE

Poland (PL)

  • (combination) TIALORID as AMILORIDE HYDROCHLORIDE

South Africa (ZA)

  • (combination) ACUMOD as AMILORIDE HYDROCHLORIDE
  • (combination) AMILORETIC as AMILORIDE HYDROCHLORIDE
  • (combination) BETARETIC as AMILORIDE HYDROCHLORIDE
  • (combination) DEZRETIC as AMILORIDE HYDROCHLORIDE
  • (combination) LORETIC as AMILORIDE HYDROCHLORIDE
  • (combination) MODURETIC as AMILORIDE HYDROCHLORIDE
  • (combination) SERVATRIN as AMILORIDE HYDROCHLORIDE

Spain (ES)

  • (combination) AMERIDE as AMILORIDE HYDROCHLORIDE
  • (combination) DIUZINE as AMILORIDE HYDROCHLORIDE
  • (combination) KALTEN as AMILORIDE HYDROCHLORIDE

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

  • (combination) FRUMIL as AMILORIDE HYDROCHLORIDE ANHYDROUS
  • (combination) MODURETIC as AMILORIDE HYDROCHLORIDE

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

 
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