Amiloride

Chemical formula: C₆H₈ClN₇O  Molecular mass: 229.627 g/mol  PubChem compound: 16231

Active ingredient description

Amiloride has mild diuretic and anti-hypertensive activity. It acts primarily in the distal tubule and does not require aldosterone for its action. Amiloride is a mild natriuretic which does not initiate a concomitant decrease in potassium levels.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C03DB01 Amiloride C Cardiovascular system → C03 Diuretics → C03D Potassium-sparing agents → C03DB Other potassium-sparing agents
Discover more medicines within C03DB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
AMILORIDE ROSEMONT Oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 2016-88-8
CAS Substance: 2609-46-3
DrugBank Drug: DB00594
KEGG Drug: D07447
PubChem Compound: 16231
RxNorm Ingredient: 644
SNOMED-CT Concept: 387503008
Amiloride (substance)
UNII Identifier: 7DZO8EB0Z3
AMILORIDE

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