Aminolevulinic acid

Chemical formula: C₅H₉NO₃  Molecular mass: 131.13 g/mol  PubChem compound: 137

Therapeutic indications

Aminolevulinic acid is indicated for:

Visualisation of malignant glioma

Population group: only adults (18 years old or older)

5-aminolevulinic acid is indicated in adult for visualisation of malignant tissue during surgery for malignant glioma (WHO grade III and IV).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Actinic keratosis and field cancerization

Population group: only adults (18 - 65 years old)

Treatment of actinic keratosis of mild to moderate severity (Olsen grade 1 to 2) and of field cancerization in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Basal cell carcinoma, unsuitable for surgical treatm

Population group: only adults (18 - 65 years old)

Treatment of superficial and/or nodular basal cell carcinoma unsuitable for surgical treatment due to possible treatment-related morbidity and/or poor cosmetic outcome in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Aminolevulinic acid is contraindicated in the following cases:

Porphyria

Porphyria

Pregnancy

Pregnancy

Lactation

Lactation

Photosensitizing agent

† Photosensitising agent

Known photodermatoses of varying pathology and frequency, diseases precipitated or aggravated by exposure to sun light

at least one of
Photosensitivity
Xeroderma pigmentosum
Lupus erythematosus
Pemphigus erythematosus

Bleeding lesions

Bleeding skin

Skin diseases, tattoos

at least one of
Dermatosis
Crystal violet tattoo
Decorative tattoo
Iatrogenic tattoo
Occupational tattoo
Tattoo of skin of left cheek
Tattoo of skin of perioral region of face
Tattoo of skin of right cheek

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