Acridinyl Anisidide Other names: Amsacrine

Chemical formula: C₂₁H₁₉N₃O₃S  Molecular mass: 393.459 g/mol  PubChem compound: 2179

Active ingredient description

Amsidine is a sterile antitumour chemotherapeutic agent for intravenous infusion. Although not completely clarified, the mode of action of amsacrine is related to its property of binding the DNA through intercalation and external (electrostatic) forces.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
L01XX01
Amsacrine
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
AMSIDINE 50mg/ml Concentrate and solvent for solution for infusion
Health Products Regulatory Authority (IE)
MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 51264-14-3
DrugBank Drug: DB00276
KEGG Drug: D02321
PubChem Compound: 2179
RxNorm Ingredient: 739
SNOMED-CT Concept: 391774005
Amsacrine (substance)
UNII Identifier: 00DPD30SOY
AMSACRINE

Medicines

Acridinyl Anisidide is an active ingredient of these brands:

Austria (AT)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Netherlands (NL)

Poland (PL)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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