Acridinyl Anisidide

Also known as: Amsacrine

Active ingredient description

Amsidine is a sterile antitumour chemotherapeutic agent for intravenous infusion. Although not completely clarified, the mode of action of amsacrine is related to its property of binding the DNA through intercalation and external (electrostatic) forces.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
L01XX01
Amsacrine
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
AMSIDINE 50mg/ml Concentrate and solvent for solution for infusion
Summary of Product Characteristics (SPC)
NL

Medicines

Acridinyl Anisidide is the active ingredient of these drugs:

Drug
Countries
AMCIDINE

Estonia

AMEKRIN

Finland

AMSALYO

Estonia France

AMSIDINE

Estonia Ireland Netherlands United Kingdom

AMSIDYL

Austria Estonia Poland

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₁H₁₉N₃O₃S
Molecular mass: 393.459 g/mol

External identifiers

CAS Substance: 51264-14-3
DrugBank Drug: DB00276
KEGG Drug: D02321
PubChem Compound: 2179
RxNorm Ingredient: 739
SNOMED-CT Concept: 391774005
Amsacrine (substance)
UNII Identifier: 00DPD30SOY
AMSACRINE
 
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