Aprepitant

Chemical formula: C₂₃H₂₁F₇N₄O₃  Molecular mass: 534.427 g/mol  PubChem compound: 135413536

Active ingredient description

Aprepitant is a selective high-affinity antagonist at human substance P neurokinin 1 (NK1) receptors.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A04AD12 Aprepitant A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AD Other antiemetics
Discover more medicines within A04AD12

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
EMEND Hard capsule European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 170729-80-3
DrugBank Drug: DB00673
KEGG Drug: D02968
PubChem Compound: 135413536
RxNorm Ingredient: 358255
SNOMED-CT Concept: 409205009
Aprepitant (substance)
UNII Identifier: 1NF15YR6UY
APREPITANT

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