Aprepitant

Active ingredient description

Aprepitant is a selective high-affinity antagonist at human substance P neurokinin 1 (NK1) receptors.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Aprepitant
A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AD Other antiemetics
Discover more medicines within A04AD12

Medicines

Aprepitant is the active ingredient of these drugs:

Drug
Countries

Ecuador

Germany

South Africa

Austria

United States

Austria Brazil Canada Cyprus Ecuador

South Africa

South Africa

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Molecular mass: 534.427 g/mol

External identifiers

CAS Substance: 170729-80-3
DrugBank Drug: DB00673
KEGG Drug: D02968
RxNorm Ingredient: 358255
SNOMED-CT Concept: 409205009
Aprepitant (substance)
UNII Identifier: 1NF15YR6UY
APREPITANT