ATC Group: A04AD12 Aprepitant

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of A04AD12 in the ATC hierarchy

Level Code Title
1 A Alimentary tract and metabolism
2 A04 Antiemetics and antinauseants
3 A04A Antiemetics and antinauseants
4 A04AD Other antiemetics
5 A04AD12 Aprepitant

Defined daily dose

The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.

Route Amount
ORAL - Oral 95 mg
PAREN - Parenteral 95 mg

Active ingredients in A04AD12

Active Ingredient Description
Aprepitant

Aprepitant is a selective high-affinity antagonist at human substance P neurokinin 1 (NK1) receptors.

Fosaprepitant

Fosaprepitant is the prodrug of aprepitant and when administered intravenously is converted rapidly to aprepitant. The contribution of fosaprepitant to the overall antiemetic effect has not fully been characterised, but a transient contribution during the initial phase cannot be ruled out.

Related product monographs

Title Information Source Document Type  
EMEND Hard capsule European Medicines Agency (EU) MPI, EU: SmPC
EMEND IV Fosaprepitant for injection Health Products and Food Branch (CA) MPI, CA: SPM
IVEMEND Powder for solution for infusion European Medicines Agency (EU) MPI, EU: SmPC

Medicines in this ATC group

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Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.