Fosaprepitant

Chemical formula: C₂₃H₂₂F₇N₄O₆P  Molecular mass: 614.407 g/mol  PubChem compound: 219090

Active ingredient description

Fosaprepitant is the prodrug of aprepitant and when administered intravenously is converted rapidly to aprepitant. The contribution of fosaprepitant to the overall antiemetic effect has not fully been characterised, but a transient contribution during the initial phase cannot be ruled out.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
A04AD12 Aprepitant A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AD Other antiemetics
Discover more medicines within A04AD12

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 IVEMEND Powder for solution for infusion MPI, EU: SmPC European Medicines Agency (EU)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 172673-20-0
CAS Substance: 265121-04-8
DrugBank Drug: DB06717
KEGG Drug: D06597
PubChem Compound: 219090
RxNorm Ingredient: 358255
SNOMED-CT Concept: 429825009
Fosaprepitant (substance)
UNII Identifier: 6L8OF9XRDC
FOSAPREPITANT

Medicines

Fosaprepitant is an active ingredient of these brands:

Australia (AU)

Austria (AT)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Brazil (BR)

  • EMEND IV as FOSAPREPITANT DIMEGLUMINE
  • FOZA as FOSAPREPITANT DIMEGLUMINE

Canada (CA)

  • EMEND IV as FOSAPREPITANT DIMEGLUMINE
  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Croatia (HR)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Estonia (EE)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Finland (FI)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Hong Kong (HK)

Ireland (IE)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Italy (IT)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Japan (JP)

Lithuania (LT)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Mexico (MX)

Netherlands (NL)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Poland (PL)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Romania (RO)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Singapore (SG)

South Africa (ZA)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Spain (ES)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Turkey (TR)

United Kingdom (UK)

  • IVEMEND as FOSAPREPITANT DIMEGLUMINE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
Next: Usage >

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.

⇈