Benzathine benzylpenicillin
Also known as: Penicillin G benzathine
Brand names: BICILLIN C-R (in combination) BICILLIN L-A
Description
Semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine. Benzathine benzylpenicillin binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis.
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