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Brinzolamide

Description

Brinzolamide is an inhibitor of carbonic anhydrase II (CA-II). Carbonic anhydrase (CA) is an enzyme found in many tissues of the body, including the eye. Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humour secretion resulting in a reduction in intraocular pressure (IOP) which is a major risk factor in the pathogenesis of optic nerve damage and glaucomatous visual field loss.

ATC Classification

Code
Title
Category
S01EC04
Brinzolamide
S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EC Carbonic anhydrase inhibitors

Trade names

Trade name
Countries

Australia Austria Canada Cyprus France

Australia

Trade names (in combination): AZARGA SIMBRINZA

Product Monographs

Monograph
Type
Country
AZOPT Eye drops, suspension
MPI, EU: SmPC