Cefuroxime

Active ingredient description

Cefuroxime inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins (PBPs). This results in the interruption of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell lysis and death.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Cefuroxime
J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01D Other beta-lactam antibacterials → J01DC Second-generation cephalosporins
Discover more medicines within J01DC02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK

Medicines

Cefuroxime is the active ingredient of these drugs:

Drug
Countries

Turkey

Hong Kong South Africa

Ecuador

Ireland

Austria Finland France Hong Kong Netherlands

South Africa

Turkey

Hong Kong

Cyprus Estonia Hong Kong Lithuania Romania

Ecuador

Singapore

South Africa

Ecuador

Poland

Poland

Turkey

South Africa

Romania

Turkey

Hong Kong

Poland

Turkey

Ireland

Singapore

Turkey

South Africa

South Africa

Ecuador

Cyprus Germany Turkey

Ecuador

Ecuador

Turkey

Ecuador

Hong Kong

Ecuador

Hong Kong

Ecuador

Ecuador

Ecuador Poland South Africa

South Africa

Hong Kong

South Africa

Austria

Italy

Hong Kong

Estonia Germany

Turkey

Hong Kong

Ecuador

Estonia Hong Kong Poland

Ecuador

Turkey

France

Turkey

Cyprus

Ecuador

Italy

Brazil

South Africa

Brazil

Turkey

Turkey

Turkey

Italy

Ecuador

Turkey

Spain

Lithuania

Lithuania

Turkey

Turkey

Turkey

Turkey

Hong Kong

Singapore

Poland

Poland

Italy

Turkey

Tunisia

Austria Estonia Lithuania Netherlands Poland

Ecuador

Ecuador Estonia Hong Kong Lithuania Poland

Hong Kong

Ecuador Poland

Spain

Turkey

South Africa

South Africa

Hong Kong

Brazil

Tunisia

Cyprus New Zealand

Brazil Cyprus Estonia Finland Hong Kong

Australia Austria Brazil Cyprus Ecuador

Tunisia

South Africa

Poland

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₆H₁₆N₄O₈S
Molecular mass: 424.385 g/mol

External identifiers

CAS Substance: 55268-75-2
CAS Substance: 56238-63-2
CAS Substance: 64544-07-6
DrugBank Drug: DB01112
KEGG Drug: D00262
PubChem Compound: 5479529
RxNorm Ingredient: 2194
SNOMED-CT Concept: 372833007
Cefuroxime (substance)
UNII Identifier: O1R9FJ93ED
CEFUROXIME