Cefuroxime
Chemical formula: C₁₆H₁₆N₄O₈S Molecular mass: 424.385 g/mol PubChem compound: 5479529
Active ingredient description
Cefuroxime inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins (PBPs). This results in the interruption of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell lysis and death.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| J01DC02 | Cefuroxime | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01D Other beta-lactam antibacterials → J01DC Second-generation cephalosporins |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| ZINACEF Powder for injection / infusion | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| ZINNAT Film-coated tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Medicines
Cefuroxime is an active ingredient of these brands:
Albania (AL)
Australia (AU)
Austria (AT)
Brazil (BR)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)France (FR)Germany (DE)Hong Kong (HK)
Ireland (IE)Israel (IL)Italy (IT)Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)New Zealand (NZ)Nigeria (NG)
Poland (PL)
Romania (RO)Singapore (SG)
South Africa (ZA)
Spain (ES)Tunisia (TN)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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