Cefuroxime

Chemical formula: C₁₆H₁₆N₄O₈S  Molecular mass: 424.385 g/mol  PubChem compound: 5479529

Active ingredient description

Cefuroxime inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins (PBPs). This results in the interruption of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell lysis and death.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01DC02 Cefuroxime J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01D Other beta-lactam antibacterials → J01DC Second-generation cephalosporins
Discover more medicines within J01DC02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ZINACEF Powder for injection / infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ZINNAT Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 55268-75-2
CAS Substance: 56238-63-2
CAS Substance: 64544-07-6
DrugBank Drug: DB01112
KEGG Drug: D00262
PubChem Compound: 5479529
RxNorm Ingredient: 2194
SNOMED-CT Concept: 372833007
Cefuroxime (substance)
UNII Identifier: O1R9FJ93ED
CEFUROXIME

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