Chemical formula: C₂₄H₂₈ClN₅O₃  Molecular mass: 469.97 g/mol  PubChem compound: 10660

Active ingredient description

Dimenhydrinate is a theoclate salt of the ethanolamine derivative diphenhydramine. It exhibits reversible competitive antagonism with histamine for the capture of H1 receptors. It has anticholinergic (antimuscarinic) properties that explain the anti-emetic action of the drug in cases of labyrinthial irritation (nausea, vertigo), and the central suppression it causes.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R06AA11 R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AA Aminoalkyl ethers
Discover more medicines within R06AA11

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DIMENHYDRINATE Tablet FDA, National Drug Code (US) MPI, US: SPL/Old
DIMENHYDRINATE Solution for injection FDA, National Drug Code (US) MPI, US: SPL/Old
DIMENHYDRINATE Solution for injection / Suppositories Health Products and Food Branch (CA) MPI, CA: SPM

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 523-87-5
DrugBank Drug: DB00985
KEGG Drug: D00520
PubChem Compound: 10660
RxNorm Ingredient: 3444
SNOMED-CT Concept: 387469006
Dimenhydrinate (substance)
UNII Identifier: JB937PER5C


Dimenhydrinate is an active ingredient of these brands:

Austria (AT)

Brazil (BR)

Canada (CA)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Israel (IL)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Poland (PL)

Romania (RO)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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