Doxorubicin Other names: Doxorubicin hydrochloride

Chemical formula: C₂₇H₂₉NO₁₁  Molecular mass: 543.519 g/mol  PubChem compound: 31703

Active ingredient description

Doxorubicin is a cytotoxic anthracycline antibiotic obtained from Streptomyces peucetius var. caesius. The exact mechanism of the antitumour activity of doxorubicin is not known. It is generally believed that inhibition of DNA, RNA and protein synthesis is responsible for the majority of the cytotoxic effects.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01DB01 Doxorubicin L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01D Cytotoxic antibiotics and related substances → L01DB Anthracyclines and related substances
Discover more medicines within L01DB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CAELYX Concentrate for solution for infusion European Medicines Agency (EU) MPI, EU: SmPC
DOXORUBICIN Concentrate for solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ADRIAMYCIN Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 23214-92-8
CAS Substance: 25316-40-9
DrugBank Drug: DB00997
KEGG Drug: D03899
PubChem Compound: 31703
RxNorm Ingredient: 3639
SNOMED-CT Concept: 372817009
Doxorubicin (substance)
UNII Identifier: 80168379AG
DOXORUBICIN

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