Estriol Other names: Oestriol

Chemical formula: C₁₈H₂₄O₃  Molecular mass: 288.381 g/mol  PubChem compound: 5756

Active ingredient description

Estriol is a steroid, a weak estrogen, specifically an agonist of the estrogen receptors ERα and ERβ. It is one of three major endogenous estrogens, the others being estradiol and estrone.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G03CA04 Estriol G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03C Estrogens → G03CA Natural and semisynthetic estrogens, plain
Discover more medicines within G03CA04
G03CC06 Estriol G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03C Estrogens → G03CC Estrogens, combinations with other drugs
Discover more medicines within G03CC06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
OVESTIN Vaginal cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 50-27-1
DrugBank Drug: DB04573
KEGG Drug: D00185
PubChem Compound: 5756
RxNorm Ingredient: 4094
SNOMED-CT Concept: 73723004
Estriol (substance)
UNII Identifier: FB33469R8E
ESTRIOL

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