Chemical formula: C₂₀H₂₁N₃O Molecular mass: 319.408 g/mol PubChem compound: 6433090
Imidafenacin is an antagonist of muscarinic cholinergic receptors and used for treatments of overactive bladder. Imidafenacin antagonizes subtypes M3 and M1 in vitro. In the urinary bladder, imidafenacin inhibits acetylcholine release by antagonizing subtype M1 and contraction of smooth muscles by antagonizing subtype M3. Compared with the inhibitory effect on the salivary gland, imidafenacin shows higher inhibitory effect on the urinary bladder contraction, probably indicating efficacy and safety of these products in the clinical practice.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G04BD14 | G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BD Urinary antispasmodics | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| URITOS / URITOS OD Tablet | Web Search | MPI, US: SPL/Old |
Imidafenacin is an active ingredient of these brands:
Ecuador (EC)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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