Indapamide

Chemical formula: C₁₆H₁₆ClN₃O₃S  Molecular mass: 365.835 g/mol  PubChem compound: 3702

Active ingredient description

Indapamide is a sulfonamide derivative with an indole ring, pharmacologically related to thiazide diuretics, which acts by inhibiting the reabsorption of sodium in the cortical dilution segment. It increases the urinary excretion of sodium and chlorides and, to a lesser extent, the excretion of potassium and magnesium, thereby increasing urine output and having an antihypertensive action.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C03BA11 Indapamide C Cardiovascular system → C03 Diuretics → C03B Low-ceiling diuretics, excl. thiazides → C03BA Sulfonamides, plain
Discover more medicines within C03BA11

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NATRILIX Prolonged-release tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 26807-65-8
DrugBank Drug: DB00808
KEGG Drug: D00345
PubChem Compound: 3702
RxNorm Ingredient: 5764
SNOMED-CT Concept: 387419003
Indapamide (substance)
UNII Identifier: F089I0511L
INDAPAMIDE

Medicines

Indapamide is an active ingredient of these brands:

Albania (AL)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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