Methronidazole

Also known as: Metronidazole

Active ingredient description

Metronidazole is an anti-infectious drug belonging to the pharmacotherapeutic group of nitroimidazole derivatives, which have effect mainly on strict anaerobes. This effect is probably caused by interaction with DNS and different metabolites.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Metronidazole
A Alimentary tract and metabolism → A01 Stomatological preparations → A01A Stomatological preparations → A01AB Antiinfectives and antiseptics for local oral treatment
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Metronidazole
D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06B Chemotherapeutics for topical use → D06BX Other chemotherapeutics
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Metronidazole
G Genito urinary system and sex hormones → G01 Gynecological antiinfectives and antiseptics → G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS → G01AF Imidazole derivatives
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Metronidazole
J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01X Other antibacterials → J01XD Imidazole derivatives
Discover more medicines within J01XD01
Metronidazole
P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01A Agents against amoebiasis and other protozoal diseases → P01AB Nitroimidazole derivatives
Discover more medicines within P01AB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK
Structured Product Labeling (SPL)
US
Summary of Product Characteristics (SPC)
UK
Structured Product Labeling (SPL/PLR)
US
Summary of Product Characteristics (SPC)
UK

Medicines

Methronidazole is the active ingredient of these drugs:

Drug
Countries

United Kingdom

Ecuador

South Africa

South Africa

Ecuador

South Africa

Cyprus United Kingdom

Austria

South Africa

Tunisia

Estonia Germany Lithuania Poland

Ecuador

South Africa

South Africa

Hong Kong

Brazil

Cyprus New Zealand

Cyprus

South Africa

Hong Kong

Lithuania

Brazil

Ecuador

Hong Kong

Hong Kong

Brazil

Australia Brazil Canada Cyprus Ecuador

Cyprus

South Africa

Hong Kong

Hong Kong

Estonia

France Poland

Brazil

Brazil

Cyprus Hong Kong

Ecuador

Singapore

Brazil

Hong Kong

South Africa

South Africa

Hong Kong

South Africa

Singapore South Africa

United States

Canada South Africa United Kingdom United States

Australia Hong Kong New Zealand Tunisia

Tunisia

United States

Brazil

Australia

Brazil

Hong Kong

Estonia Lithuania Netherlands United Kingdom

Ireland

Ecuador

Hong Kong

South Africa

South Africa

Brazil

Canada

Cyprus

South Africa

Austria

Brazil

Ecuador

Ecuador

Hong Kong Singapore

Canada United States

South Africa

Estonia

United States

Tunisia

United States

Hong Kong

Finland

Netherlands United Kingdom

France

Poland

Austria Brazil Ecuador Estonia Finland

South Africa

Lithuania

South Africa

Hong Kong

Tunisia

Ecuador

Hong Kong

Hong Kong

Hong Kong South Africa

Lithuania

New Zealand

Finland

Singapore

Brazil

Hong Kong

Italy Tunisia

United States

Mexico

Ecuador

Finland United Kingdom

United Kingdom

Methronidazole is also found within below combination drugs:

ACROMONA , ACROMONA ADVANCE , BI-MISSILOR , BI-SPIRAZOL , BI-SPIROGYL , BIO-VAGIN , BIOGYL , BIRODOGYL , COLPATRIN , COLPIST MT , COLPISTAR , COLPISTATIN , COLPOFILIN MAX , ENTAMIZOLE , EQUIFEM , ESKAPAR COMPUESTO , ETRON NISTATINA , FANGAN PLUS , FEMINAL , FLAGENASE , FLAGYL COMP , FLAGYL NISTATINA , FLAGYSTATIN , GYNALGIN , GYNOTRAN , HELIPAK A , KLION-D , KOLPITRAT , MECLON , METODINE , NEO PELVICILLIN , NISTRON , OGYL , PYLERA , RHODOGIL , RODOGYL , SPIRAMIZOLE , SPIRAZOL , SPIROGYL , SUFREXAL COMBI , TERGYNAN , TRICOMAX , TRICOXIN , VAGITROL-V

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₆H₉N₃O₃
Molecular mass: 171.154 g/mol

External identifiers

CAS Substance: 13182-89-3
CAS Substance: 443-48-1
DrugBank Drug: DB00916
KEGG Drug: D00409
PubChem Compound: 4173
RxNorm Ingredient: 6922
SNOMED-CT Concept: 372602008
Metronidazole (substance)
UNII Identifier: 140QMO216E
METRONIDAZOLE