Miconazole

Chemical formula: C₁₈H₁₄Cl₄N₂O  Molecular mass: 416.129 g/mol  PubChem compound: 4189

Active ingredient description

Miconazole possesses an antifungal activity against the common dermatophytes and yeasts as well as an antibacterial activity against certain gram-positive bacilli and cocci. Its activity is based on the inhibition of the ergosterol biosynthesis in fungi and the change in the composition of the lipid components in the membrane, resulting in fungal cell necrosis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A01AB09 Miconazole A Alimentary tract and metabolism → A01 Stomatological preparations → A01A Stomatological preparations → A01AB Antiinfectives and antiseptics for local oral treatment
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A07AC01 Miconazole A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07A Intestinal antiinfectives → A07AC Imidazole derivatives
Discover more medicines within A07AC01
D01AC02 Miconazole D Dermatologicals → D01 Antifungals for dermatological use → D01A Antifungals for topical use → D01AC Imidazole and triazole derivatives
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G01AF04 Miconazole G Genito urinary system and sex hormones → G01 Gynecological antiinfectives and antiseptics → G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS → G01AF Imidazole derivatives
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J02AB01 Miconazole J Antiinfectives for systemic use → J02 Antimycotics for systemic use → J02A Antimycotics for systemic use → J02AB Imidazole derivatives
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S02AA13 Miconazole S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives
Discover more medicines within S02AA13

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DAKTARIN Oral gel Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
GYNO-DAKTARIN Vaginal cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
DAKTARIN INTENSIV Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
DAKTARIN Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 22832-87-7
CAS Substance: 22916-47-8
DrugBank Drug: DB01110
KEGG Drug: D00882
PubChem Compound: 4189
RxNorm Ingredient: 6932
SNOMED-CT Concept: 372738006
Miconazole (substance)
UNII Identifier: 7NNO0D7S5M
MICONAZOLE

Medicines

Miconazole is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

  • CANDIPLAS
  • DAFRIN as MICONAZOLE NITRATE
  • DECOZOL
  • DERMON as MICONAZOLE NITRATE
  • GYNO-MICOZO as MICONAZOLE NITRATE
  • MICROTIN as MICONAZOLE NITRATE
  • MYCOCAN as MICONAZOLE NITRATE
  • NAZODERM as MICONAZOLE NITRATE
  • TARA as MICONAZOLE NITRATE
  • TINAZOL as MICONAZOLE NITRATE
  • ZARIN as MICONAZOLE NITRATE

  • (combination) ACCURE as MICONAZOLE NITRATE
  • (combination) BOSTON as MICONAZOLE NITRATE
  • (combination) CANDIPLAS H
  • (combination) CARIDERMA as MICONAZOLE NITRATE
  • (combination) CLOTASODINE as MICONAZOLE NITRATE
  • (combination) CLOTASONE as MICONAZOLE NITRATE
  • (combination) CO-BETA-N as MICONAZOLE NITRATE
  • (combination) DAFRIN-H as MICONAZOLE NITRATE
  • (combination) DAKTACORT as MICONAZOLE NITRATE
  • (combination) DECOCORT as MICONAZOLE NITRATE
  • (combination) DERMIC as MICONAZOLE NITRATE
  • (combination) ELLAWON as MICONAZOLE NITRATE
  • (combination) EUGENCORT as MICONAZOLE NITRATE
  • (combination) FLURADERM as MICONAZOLE NITRATE
  • (combination) FUBETA as MICONAZOLE NITRATE
  • (combination) FUHARKIN as MICONAZOLE NITRATE
  • (combination) FUNGA-F as MICONAZOLE NITRATE
  • (combination) FUOCORTE-F as MICONAZOLE NITRATE
  • (combination) HAVANDA as MICONAZOLE NITRATE
  • (combination) HYDRO-FUNGA as MICONAZOLE NITRATE
  • (combination) KENDERM as MICONAZOLE NITRATE
  • (combination) KENNETIC as MICONAZOLE NITRATE
  • (combination) KENOVAN as MICONAZOLE NITRATE
  • (combination) LONGAXON as MICONAZOLE NITRATE
  • (combination) MICOSONE as MICONAZOLE NITRATE
  • (combination) MINAZOLE as MICONAZOLE NITRATE
  • (combination) POTADERM-FORTE as MICONAZOLE NITRATE
  • (combination) PROHEALAN as MICONAZOLE NITRATE
  • (combination) SIROLIN as MICONAZOLE NITRATE
  • (combination) TAIRO as MICONAZOLE NITRATE
  • (combination) TARA-PLUS as MICONAZOLE NITRATE
  • (combination) TETCOM as MICONAZOLE NITRATE
  • (combination) TINACORT as MICONAZOLE NITRATE
  • (combination) TOLNAZOLE as MICONAZOLE NITRATE
  • (combination) VODADERM as MICONAZOLE NITRATE
  • (combination) XATIM as MICONAZOLE NITRATE
  • (combination) ZARICORT as MICONAZOLE NITRATE

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

  • DAKTARIN as MICONAZOLE NITRATE

  • (combination) KLION-D as MICONAZOLE NITRATE

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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