Paclitaxel

Active ingredient description

Paclitaxel is an antimicrotubule agent that promotes the assembly of microtubules from tubulin dimers and stabilises microtubules by preventing depolymerisation. This stability results in the inhibition of the normal dynamic reorganisation of the microtubule network that is essential for vital interphase and mitotic cellular functions.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Paclitaxel
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01C Plant alkaloids and other natural products → L01CD Taxanes
Discover more medicines within L01CD01

Medicines

Paclitaxel is the active ingredient of these drugs:

Drug
Countries

Australia Austria Brazil Canada Cyprus

Singapore

Brazil

Hong Kong New Zealand Singapore South Africa Tunisia

Austria Estonia Finland Ireland Lithuania

Singapore

Tunisia

Ecuador Tunisia

Austria Hong Kong Singapore South Africa Tunisia

Brazil

Singapore

Singapore

South Africa

Brazil

Brazil

New Zealand

Finland

Lithuania

Brazil

Ecuador

Cyprus

Australia

Ecuador

Ecuador

Brazil

Hong Kong Singapore

South Africa

Austria Estonia France Ireland Lithuania

Ecuador

South Africa

Lithuania

Hong Kong Poland Tunisia

Brazil

Brazil

Ecuador

Brazil Hong Kong Singapore South Africa

Ecuador

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

P88XT4IS4D - PACLITAXEL

CAS registry number

33069-62-4 - paclitaxel

SNOMED-CT

387374002 - Paclitaxel (substance)