Promethazine

Chemical formula: C₁₇H₂₀N₂S  Molecular mass: 284.419 g/mol  PubChem compound: 4927

Active ingredient description

Promethazine is a potent, long acting, antihistamine with additional anti-emetic central sedative and anti-cholinergic properties.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D04AA10 Promethazine D Dermatologicals → D04 Antipruritics, incl. antihistamines, anesthetics, etc. → D04A Antipruritics, incl. antihistamines, anesthetics, etc. → D04AA Antihistamines for topical use
Discover more medicines within D04AA10
R06AD02 Promethazine R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AD Phenothiazine derivatives
Discover more medicines within R06AD02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PHENERGAN Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
PHENERGAN Solution for injection FDA, National Drug Code (US) MPI, US: SPL/Old
SOMINEX Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 58-33-3
CAS Substance: 60-87-7
DrugBank Drug: DB01069
KEGG Drug: D00494
PubChem Compound: 4927
RxNorm Ingredient: 8745
SNOMED-CT Concept: 256051006
Promethazine (substance)
SNOMED-CT Concept: 372871004
Promethazine (substance)
UNII Identifier: FF28EJQ494
PROMETHAZINE

Medicines

Promethazine is an active ingredient of these brands:

United States (US)

Brazil (BR)

Canada (CA)

Cyprus (CY)

France (FR)

Germany (DE)

Hong Kong (HK)

  • ANVOMIN as PROMETHAZINE TEOCLATE
  • FENAMIN as PROMETHAZINE HYDROCHLORIDE
  • FENAZIN as PROMETHAZINE HYDROCHLORIDE
  • PHENOMA as PROMETHAZINE HYDROCHLORIDE
  • PROCODYL as PROMETHAZINE HYDROCHLORIDE
  • PROMEGAN as PROMETHAZINE HYDROCHLORIDE
  • PROMIN as PROMETHAZINE HYDROCHLORIDE
  • SYNVOMIN as PROMETHAZINE TEOCLATE
  • UNI-PROZINE as PROMETHAZINE HYDROCHLORIDE
  • XEPAGAN as PROMETHAZINE HYDROCHLORIDE

  • (combination) ACTCOFED as PROMETHAZINE HYDROCHLORIDE
  • (combination) AENDY as PROMETHAZINE HYDROCHLORIDE
  • (combination) ALSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) ANMEN as PROMETHAZINE HYDROCHLORIDE
  • (combination) ANTITUSS as PROMETHAZINE HYDROCHLORIDE
  • (combination) ARACO as PROMETHAZINE HYDROCHLORIDE
  • (combination) ARISTTO as PROMETHAZINE HYDROCHLORIDE
  • (combination) ARSECOYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) BAILIE as PROMETHAZINE HYDROCHLORIDE
  • (combination) BESCOFED as PROMETHAZINE HYDROCHLORIDE
  • (combination) BOLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) BRONCOLIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) BRONKIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) BROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) CARNETTI as PROMETHAZINE HYDROCHLORIDE
  • (combination) CO-SEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) CO-TUSIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) CO-TUSIU as PROMETHAZINE HYDROCHLORIDE
  • (combination) COCLEAN as PROMETHAZINE HYDROCHLORIDE
  • (combination) COCURE as PROMETHAZINE HYDROCHLORIDE
  • (combination) CODEY as PROMETHAZINE HYDROCHLORIDE
  • (combination) COFEDPO as PROMETHAZINE HYDROCHLORIDE
  • (combination) COFFTIER as PROMETHAZINE HYDROCHLORIDE
  • (combination) COL-LERGIC as PROMETHAZINE HYDROCHLORIDE
  • (combination) COLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) COMEPHEN as PROMETHAZINE HYDROCHLORIDE
  • (combination) CONDOSA as PROMETHAZINE HYDROCHLORIDE
  • (combination) COPHENDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) COPHENSIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) CORIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) CORME as PROMETHAZINE HYDROCHLORIDE
  • (combination) COSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) COSO as PROMETHAZINE HYDROCHLORIDE
  • (combination) COSOTAL as PROMETHAZINE HYDROCHLORIDE
  • (combination) COTIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) CROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) DECOFFA as PROMETHAZINE HYDROCHLORIDE
  • (combination) DEXCOFED as PROMETHAZINE HYDROCHLORIDE
  • (combination) DEXTRODYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) DHASEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) ECOMET as PROMETHAZINE HYDROCHLORIDE
  • (combination) ECOSIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) EDENA as PROMETHAZINE HYDROCHLORIDE
  • (combination) EENDEL LIGHT as PROMETHAZINE HYDROCHLORIDE
  • (combination) EFENDEL as PROMETHAZINE HYDROCHLORIDE
  • (combination) EPHCOUGH as PROMETHAZINE HYDROCHLORIDE
  • (combination) EPHECO as PROMETHAZINE HYDROCHLORIDE
  • (combination) EPHEDYL DM as PROMETHAZINE HYDROCHLORIDE
  • (combination) EPHENDYLN as PROMETHAZINE HYDROCHLORIDE
  • (combination) EUROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) FAMISEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) FENCO COUGH as PROMETHAZINE HYDROCHLORIDE
  • (combination) FENCOLIN COUGH as PROMETHAZINE HYDROCHLORIDE
  • (combination) FENDIL as PROMETHAZINE HYDROCHLORIDE
  • (combination) FENDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) FERRALI as PROMETHAZINE HYDROCHLORIDE
  • (combination) FESCOFED as PROMETHAZINE HYDROCHLORIDE
  • (combination) FOLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) FRICOLIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) GOBY COUGH as PROMETHAZINE HYDROCHLORIDE
  • (combination) GROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) HOLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) JENDEL as PROMETHAZINE HYDROCHLORIDE
  • (combination) JENDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) KENDEL as PROMETHAZINE HYDROCHLORIDE
  • (combination) KOLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) KROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) LAMBAR as PROMETHAZINE HYDROCHLORIDE
  • (combination) LAVENDA as PROMETHAZINE HYDROCHLORIDE
  • (combination) LOLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) MARSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) MARUSEN as PROMETHAZINE HYDROCHLORIDE
  • (combination) MECODIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) MEPHENDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) MERSIDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) MESADIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) METASIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) METHARINE as PROMETHAZINE HYDROCHLORIDE
  • (combination) METHOPIME as PROMETHAZINE HYDROCHLORIDE
  • (combination) METHORSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) METOFEN COMPOUND as PROMETHAZINE HYDROCHLORIDE
  • (combination) MONIC COUGH as PROMETHAZINE HYDROCHLORIDE
  • (combination) MROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) MUCOPROM as PROMETHAZINE HYDROCHLORIDE
  • (combination) MYCODIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) NASEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) NAVOSE as PROMETHAZINE HYDROCHLORIDE
  • (combination) NOLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) OROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) PECOLIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) PHECOMIN-N as PROMETHAZINE HYDROCHLORIDE
  • (combination) PHENAZOL as PROMETHAZINE HYDROCHLORIDE
  • (combination) PHENCOUGH as PROMETHAZINE HYDROCHLORIDE
  • (combination) PHENSEDYN as PROMETHAZINE HYDROCHLORIDE
  • (combination) PHENTAGON as PROMETHAZINE HYDROCHLORIDE
  • (combination) PHENZINCO as PROMETHAZINE HYDROCHLORIDE
  • (combination) POCODYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) POLESEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) POSODIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) PRADASON as PROMETHAZINE HYDROCHLORIDE
  • (combination) PRESEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) PRO-COTIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) PRO-PHECO as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROCODINE as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROCOSED as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROCOTUSS as PROMETHAZINE HYDROCHLORIDE
  • (combination) PRODEX as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROPHENIN ELIXIR as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROSEDIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROSEDINE as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROSODIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) QUENCOL as PROMETHAZINE HYDROCHLORIDE
  • (combination) RROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) SEDILIX as PROMETHAZINE HYDROCHLORIDE
  • (combination) SEDYLIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) SENDY as PROMETHAZINE HYDROCHLORIDE
  • (combination) SOLSEDYL COUGH as PROMETHAZINE HYDROCHLORIDE
  • (combination) SUPHENIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) SURSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) SURTUSSIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) TOLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) TOUSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) TROSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) TUCOSOL as PROMETHAZINE HYDROCHLORIDE
  • (combination) TUCOUSOL as PROMETHAZINE HYDROCHLORIDE
  • (combination) U-PHENCO as PROMETHAZINE HYDROCHLORIDE
  • (combination) VANDAFU as PROMETHAZINE HYDROCHLORIDE
  • (combination) VOLSEDYL COUGH as PROMETHAZINE HYDROCHLORIDE
  • (combination) WASEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) WINSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) XOLSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) ZOLLAR as PROMETHAZINE HYDROCHLORIDE

Ireland (IE)

Israel (IL)

Japan (JP)

  • HIBERNA as PROMETHAZINE HYDROCHLORIDE
  • PYRETHIA as PROMETHAZINE HYDROCHLORIDE

  • (combination) MARIKINA as PROMETHAZINE METHYLENEDISALICYLATE
  • (combination) SALAZAC as PROMETHAZINE METHYLENEDISALICYLATE
  • (combination) SELAPINA as PROMETHAZINE METHYLENEDISALICYLATE
  • (combination) TOWATHIEM as PROMETHAZINE METHYLENEDISALICYLATE

Malta (MT)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

  • PROMAGEN as PROMETHAZINE HYDROCHLORIDE
  • PROZINE as PROMETHAZINE HYDROCHLORIDE
  • VOTAZINE as PROMETHAZINE TEOCLATE
  • XEPAGAN as PROMETHAZINE HYDROCHLORIDE

  • (combination) BEACODYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) BEACTAFED CO as PROMETHAZINE HYDROCHLORIDE
  • (combination) COPHADYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) COPHADYL-E as PROMETHAZINE HYDROCHLORIDE
  • (combination) DHASEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROCODIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROMEDYL-B as PROMETHAZINE HYDROCHLORIDE
  • (combination) PROMELIX as PROMETHAZINE HYDROCHLORIDE
  • (combination) RHINATHIOL PROMETHAZINE as PROMETHAZINE HYDROCHLORIDE
  • (combination) SEDILIX as PROMETHAZINE HYDROCHLORIDE
  • (combination) SUNSEDYL as PROMETHAZINE HYDROCHLORIDE
  • (combination) UNISEDYL FORTE as PROMETHAZINE HYDROCHLORIDE

South Africa (ZA)

  • BRUNAZINE as PROMETHAZINE HYDROCHLORIDE

  • (combination) DEPAIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) GO PAIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) KID-EEZE as PROMETHAZINE HYDROCHLORIDE
  • (combination) LENTOGESIC as PROMETHAZINE HYDROCHLORIDE
  • (combination) MEPROMOL as PROMETHAZINE HYDROCHLORIDE
  • (combination) PEDPAIN as PROMETHAZINE HYDROCHLORIDE
  • (combination) PYNMED PAIN AND FEVER as PROMETHAZINE HYDROCHLORIDE
  • (combination) SYNALEVE PAEDIATRIC as PROMETHAZINE HYDROCHLORIDE
  • (combination) VACUDOL as PROMETHAZINE HYDROCHLORIDE
  • (combination) WESTASED as PROMETHAZINE HYDROCHLORIDE

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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