Rebamipide

Chemical formula: C₁₉H₁₅ClN₂O₄  Molecular mass: 370.072 g/mol  PubChem compound: 5042

Active ingredient description

Rebamipide, a gastroprotective drug, is a compound selected from over 500 amino acid analogs of 2(1H)-quinolinone. Rebamipide stimulates prostaglandin generation in gastric mucosa and improves not only the speed but also the quality of ulcer healing. Rebamipide works by enhancing mucosal defense, scavenging free radicals and temporarily activating genes encoding cyclooxygenase-2.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A02BX14 A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) → A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
Discover more medicines within A02BX14

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MUCOSTA Tablet Web Search MPI, Generic

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 90098-04-7
DrugBank Drug: DB11656
KEGG Drug: D01121
PubChem Compound: 5042
UNII Identifier: LR583V32ZR
REBAMIPIDE

Medicines

Rebamipide is an active ingredient of these brands:

Japan (JP)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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