Chemical formula: C₁₆H₂₃NO Molecular mass: 245.366 g/mol
As a skeletal muscle relaxant whose prototype is mephenesine, tolperisone induces ataxia and muscle weakness in animal models by acting on the central nervous system at the spinal level. In fact it inhibits polysynaptic and monosynaptic reflexes with little action on non-reflex muscle response and without potentiating the phenobarbital sleep.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M02AX06 | M Musculo-skeletal system → M02 Topical products for joint and muscular pain → M02A Topical products for joint and muscular pain → M02AX Other topical products for joint and muscular pain | |
| M03BX04 | Tolperisone | M Musculo-skeletal system → M03 Muscle relaxants → M03B Muscle relaxants, centrally acting agents → M03BX Other centrally acting agents |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MYDOFLEX Film-coated tablet | Υπουργείο Υγείας (CY) | MPI, EU: SmPC |
Tolperisone is an active ingredient of these brands:
Cyprus (CY)Estonia (EE)
Germany (DE)
Lithuania (LT)
Mexico (MX)
Netherlands (NL)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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