ATC Group: M03BX Other centrally acting agents

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of M03BX in the ATC hierarchy

Level Code Title
1 M Musculo-skeletal system
2 M03 Muscle relaxants
3 M03B Muscle relaxants, centrally acting agents
4 M03BX Other centrally acting agents

Group M03BX contents

Code Title
M03BX01 Baclofen
M03BX02 Tizanidine
M03BX03 Pridinol
M03BX04 Tolperisone
M03BX05 Thiocolchicoside
M03BX06 Mephenesin
M03BX07 Tetrazepam
M03BX08 Cyclobenzaprine
M03BX09
M03BX30 Fenyramidol
M03BX53
M03BX55

Active ingredients in M03BX

Active Ingredient Description
Baclofen

Baclofen is an antispastic agent acting at the spinal level. A gamma-aminobutyric acid (GABA) derivative, chemically unrelated to other antispastic agents.

Cyclobenzaprine

Cyclobenzaprine relieves skeletal muscle spasm of local origin without interfering with muscle function. Cyclobenzaprine has not been shown to be effective in muscle spasm due to central nervous system disease.

Eperisone

Eperisone is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain.

Fenyramidol
Mephenesin
Pridinol

Pridinol is a piperidin- polyalcohol derivative with the chemical formula 1,1-Diphenyl-1-ol-3-piperidin-propan-methanesulfonate. Its pharmacological effect develops via an atropine-like mechanism that acts on both smooth and the striated muscles. This effect is used for the treatment of skeletal muscle tension of both central and peripheral origin.

Tetrazepam
Thiocolchicoside

Thiocolchicoside is a semisynthetic sulphide derivative of colchicoside, showing muscle relaxant pharmacological activity. In vitro thiocolchicoside binds solely with gaba receptors and glycinergic stricnine sensitive.Tivozanib

Tizanidine

Tizanidine is a centrally acting skeletal muscle relaxant. Polysynaptic signal transmission at spinal interneuron level, which is responsible for excessive muscle tone, is inhibited and muscle tone reduced.

Tolperisone

As a skeletal muscle relaxant whose prototype is mephenesine, tolperisone induces ataxia and muscle weakness in animal models by acting on the central nervous system at the spinal level. In fact it inhibits polysynaptic and monosynaptic reflexes with little action on non-reflex muscle response and without potentiating the phenobarbital sleep.

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