Chemical formula: C₂₂H₃₈O₅ Molecular mass: 382.541 g/mol PubChem compound: 5311236
Unoprostone is a prostaglandin (F2-alpha) analogue for the management of open-angle glaucoma and ocular hypertension. It is believed to reduce elevated intraocular pressure (IOP), by increasing the outflow of aqueous humor, but the exact mechanism is unknown at this time.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| S01EE02 | Unoprostone | S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EE Prostaglandin analogues |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| RESCULA Ophthalmic solution | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Unoprostone is an active ingredient of these brands:
Japan (JP)
South Africa (ZA)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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