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ATC Group: A02BC05 Esomeprazole

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A02
Drugs for acid related disorders
3
A02B
DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
4
A02BC
Proton pump inhibitors
5
A02BC05
Esomeprazole

Active Ingredients

Chemical substance
Description
Esomeprazole

Esomeprazole is the S-isomer of omeprazole and reduces gastric acid secretion through a specific targeted mechanism of action. Esomeprazole is a weak base and is concentrated and converted to the active form in the highly acidic environment of the secretory canaliculi of the parietal cell, where it inhibits the enzyme H+ K+ -ATPase – the acid pump and inhibits both basal and stimulated acid secretion.

Monographs

Monograph
Type
Country
NEXIUM Gastro-resistant granules
MPI, EU: SmPC
UK
NEXIUM Gastro-resistant tablets
MPI, EU: SmPC
UK
NEXIUM Powder for solution for injection / infusion
MPI, EU: SmPC
UK