Esomeprazole

Chemical formula: C₁₇H₁₉N₃O₃S Molecular mass: 345.416 g/mol PubChem compound: 9568614

Active ingredient description

Esomeprazole is the S-isomer of omeprazole and reduces gastric acid secretion through a specific targeted mechanism of action. Esomeprazole is a weak base and is concentrated and converted to the active form in the highly acidic environment of the secretory canaliculi of the parietal cell, where it inhibits the enzyme H+ K+ -ATPase – the acid pump and inhibits both basal and stimulated acid secretion.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code	Group title	Classification
A02BC05	Esomeprazole	A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) → A02BC Proton pump inhibitors
Discover more medicines within A02BC05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title	Information Source	Document Type
NEXIUM Powder for solution for injection / infusion	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC
NEXIUM Gastro-resistant tablet	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC
NEXIUM Gastro-resistant granules	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC

Medicines

Esomeprazole is an active ingredient of these brands:

United States (US)

NEXIUM as Esomeprazole magnesium trihydrate
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Australia (AU)

ESOPREZE
NEXAZOLE
NEXIUM as Esomeprazole magnesium trihydrate
NEXOLE
NOXICID
(combination) NEXIUM HP7

Austria (AT)

DUROTIV as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Brazil (BR)

ESIO as ESOMEPRAZOLE MAGNESIUM
ESMOG as ESOMEPRAZOLE MAGNESIUM
ESOGASTRO as ESOMEPRAZOLE MAGNESIUM
ESOMEX as ESOMEPRAZOLE MAGNESIUM
ESOP as ESOMEPRAZOLE MAGNESIUM
GAESO as ESOMEPRAZOLE MAGNESIUM
MEZOLIUM as ESOMEPRAZOLE MAGNESIUM
MEZP as ESOMEPRAZOLE SODIUM
NEXIUM as Esomeprazole magnesium trihydrate
NEXPRAZIN as ESOMEPRAZOLE MAGNESIUM
SOMPRAZ as ESOMEPRAZOLE SODIUM
YESOM as ESOMEPRAZOLE SODIUM
(combination) ESOGASTRO IBP as ESOMEPRAZOLE MAGNESIUM
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Canada (CA)

NEXIUM as Esomeprazole magnesium trihydrate
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Croatia (HR)

EMANERA as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate

Cyprus (CY)

DEMOLOX as ESOMEPRAZOLE SODIUM
ESACTIVE as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
ETEFACIN as ESOMEPRAZOLE SODIUM
NEXIUM as Esomeprazole magnesium trihydrate

Ecuador (EC)

AXASOLE
BIPET as ESOMEPRAZOLE MAGNESIUM
BIPETOL as ESOMEPRAZOLE MAGNESIUM
DEROPRAX
E-LIPROT
E-PRAZOL Q as ESOMEPRAZOLE MAGNESIUM
ELIPROT
EMUNE
ESOFAX as ESOMEPRAZOLE MAGNESIUM
ESOMAX
ESOMEZZ
ESOMEZZOL as ESOMEPRAZOLE MAGNESIUM
ESOPRAX as ESOMEPRAZOLE MAGNESIUM
ESOZ as ESOMEPRAZOLE MAGNESIUM
EZOLE as ESOMEPRAZOLE SODIUM
EZOLIUM
EZOMSOL as ESOMEPRAZOLE MAGNESIUM
FARMAPROZ
HYGGEPRAX as ESOMEPRAZOLE MAGNESIUM
JULPRAZOL
MILENIUM
NEXIUM as Esomeprazole magnesium trihydrate
NOCERTAB
RACIPER
SOMPRAZ as ESOMEPRAZOLE SODIUM
ULCEALIV as ESOMEPRAZOLE MAGNESIUM
ULCIUM
ULPEP
ULTRAPRAZOL as ESOMEPRAZOLE MAGNESIUM
(combination) ARTROX PLUS
(combination) BIENEX IBP
(combination) CELEREX as ESOMEPRAZOLE MAGNESIUM
(combination) MELOCAM DUO
(combination) OCAM PROTECT
(combination) RUMONAL PRO as ESOMEPRAZOLE MAGNESIUM

Estonia (EE)

ELFIMEST as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
ERADIZOL
ESCADRA as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
ESPEYEN
ESPRAMAG as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate
NEXMEZOL as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Finland (FI)

ACIDAL as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
NEXIUM as Esomeprazole magnesium trihydrate
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

France (FR)

INEXIUM as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate

Germany (DE)

NEXIUM as Esomeprazole magnesium trihydrate

Hong Kong (HK)

EMANERA as ESOMEPRAZOLE MAGNESIUM
ESOMESEC as ESOMEPRAZOLE STRONTIUM
ESOPEL as ESOMEPRAZOLE MAGNESIUM
ESOZ as ESOMEPRAZOLE MAGNESIUM
MAXEUM as ESOMEPRAZOLE MAGNESIUM
MAXIMA as ESOMEPRAZOLE MAGNESIUM
NEMEOL as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate
NEXPESOL as ESOMEPRAZOLE MAGNESIUM
PROSOME as ESOMEPRAZOLE MAGNESIUM
STADNEX as ESOMEPRAZOLE MAGNESIUM
VENTRA as ESOMEPRAZOLE MAGNESIUM DIHYDRATE

Ireland (IE)

EMAZOLE as ESOMEPRAZOLE SODIUM
NEXAZOLE
NEXIUM as Esomeprazole magnesium trihydrate
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Israel (IL)

ESOPRIM as ESOMEPRAZOLE SODIUM
NEXIUM as Esomeprazole magnesium trihydrate
SOLEZOL as ESOMEPRAZOLE SODIUM

Italy (IT)

ARILIAR as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
AXAGON as ESOMEPRAZOLE MAGNESIUM
COLLEZOES as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
ESODOR as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
ESOPRAL as ESOMEPRAZOLE MAGNESIUM
EZORAN
GASTRES as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
LUCEN as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate

Japan (JP)

NEXIUM as Esomeprazole magnesium trihydrate

Lithuania (LT)

ELFIMEST as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
ESCADRA as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
ESEPA
ESPRAMAG as ESOMEPRAZOLE MAGNESIUM
ETEFACIN as ESOMEPRAZOLE SODIUM
MESOPRAL
NEXIUM as Esomeprazole magnesium trihydrate
NEXMEZOL as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
SOLEZOL as ESOMEPRAZOLE SODIUM
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Malta (MT)

EMAZOLE as ESOMEPRAZOLE SODIUM
NEXIUM as Esomeprazole magnesium trihydrate

Mexico (MX)

NEXIUM as Esomeprazole magnesium trihydrate

Netherlands (NL)

NEXIUM as Esomeprazole magnesium trihydrate
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

New Zealand (NZ)

NEXIUM as Esomeprazole magnesium trihydrate

Nigeria (NG)

ESOMEGA as ESOMEPRAZOLE MAGNESIUM
ESOPHRAN as ESOMEPRAZOLE MAGNESIUM
ESOREST as ESOMEPRAZOLE MAGNESIUM
ESOSWIFT as ESOMEPRAZOLE MAGNESIUM
ESOZ as ESOMEPRAZOLE MAGNESIUM
JUBIUM as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate
STULCER as ESOMEPRAZOLE MAGNESIUM
TORZIAM as ESOMEPRAZOLE MAGNESIUM
YESOM as ESOMEPRAZOLE SODIUM
ZOLERIC as ESOMEPRAZOLE MAGNESIUM
(combination) EPROXEN

Poland (PL)

EMANERA as ESOMEPRAZOLE MAGNESIUM
ESOGASEC as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
HELIDES as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
MESOPRAL
NEXIUM as Esomeprazole magnesium trihydrate
STOMEZUL as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
TEXIBAX as ESOMEPRAZOLE MAGNESIUM

Romania (RO)

EMANERA as ESOMEPRAZOLE MAGNESIUM
HELIDES as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
NEXIUM as Esomeprazole magnesium trihydrate
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Singapore (SG)

AXIAGO as Esomeprazole magnesium trihydrate
EMANERA as ESOMEPRAZOLE MAGNESIUM
EMAZOLE as ESOMEPRAZOLE SODIUM
EPIVETIER
ESOZ as ESOMEPRAZOLE MAGNESIUM
JUBIUM as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate
SOMPRAZ as ESOMEPRAZOLE SODIUM

South Africa (ZA)

ASPEPRAZ as ESOMEPRAZOLE SODIUM
CHETOLEN as ESOMEPRAZOLE MAGNESIUM
DISPEP as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
EMZOL as ESOMEPRAZOLE SODIUM
EQUAZOLE as ESOMEPRAZOLE SODIUM
ESOMEX as ESOMEPRAZOLE MAGNESIUM
ESORAN
ESPRAWIN
GISISUM as ESOMEPRAZOLE MAGNESIUM
HETENEX as ESOMEPRAZOLE MAGNESIUM
MERPAX as ESOMEPRAZOLE MAGNESIUM
MITOGUT as ESOMEPRAZOLE SODIUM
NECTIZOLE
NESOPRAM
NEXIAM
NEXIFLUX
NEXILOK as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
NEXIPRAZ
NEXMEZOL as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
NEXOMEP as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
NEXTELL as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
REPIGUT as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
SYNTIAM as ESOMEPRAZOLE SODIUM
TRULOC as ESOMEPRAZOLE MAGNESIUM
TRUSTAN as ESOMEPRAZOLE MAGNESIUM
URDALA as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
(combination) RARZULITE
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Spain (ES)

AXIAGO as Esomeprazole magnesium trihydrate
EMANERA as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Tunisia (TN)

ACTIPP
ENOMERAL
ESOCALM as Esomeprazole magnesium trihydrate
ESOCARE as Esomeprazole magnesium trihydrate
ESOMAX
ESORAL
INEXIUM as ESOMEPRAZOLE MAGNESIUM
IPPSIUM
MESOPRAL
NEXIUM as Esomeprazole magnesium trihydrate
NEXUS
RGEO
RUGDAL
STELAR

Turkey (TR)

ENPRO as ESOMEPRAZOLE SODIUM
ESEMEPROL as ESOMEPRAZOLE SODIUM
ESMARA as ESOMEPRAZOLE SODIUM
ESNEKS as ESOMEPRAZOLE MAGNESIUM
ESOBLOK as ESOMEPRAZOLE SODIUM
ESOMEN-L as ESOMEPRAZOLE SODIUM
ESOPRAL as ESOMEPRAZOLE MAGNESIUM
ESOPRO as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
ESPOVIL as ESOMEPRAZOLE SODIUM
ESSIUM as ESOMEPRAZOLE SODIUM
ESWAZOL as ESOMEPRAZOLE SODIUM
GENIUM as ESOMEPRAZOLE SODIUM
JECTOSEM as ESOMEPRAZOLE SODIUM
MASECRIS as ESOMEPRAZOLE SODIUM
NEXFUL as ESOMEPRAZOLE SODIUM
NEXIUM as Esomeprazole magnesium trihydrate
NEXOMEP as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
NEXSTEP as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
REFASTIL as ESOMEPRAZOLE SODIUM
SITAROL as ESOMEPRAZOLE SODIUM
(combination) ESOVIP as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
(combination) VONO as ESOMEPRAZOLE MAGNESIUM DIHYDRATE

United Kingdom (UK)

EMOZUL as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
GUARDIUM as ESOMEPRAZOLE MAGNESIUM
NEXIUM as Esomeprazole magnesium trihydrate
VENTRA as ESOMEPRAZOLE MAGNESIUM DIHYDRATE
(combination) VIMOVO as ESOMEPRAZOLE MAGNESIUM

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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