Esomeprazole

Chemical formula: C₁₇H₁₉N₃O₃S  Molecular mass: 345.416 g/mol  PubChem compound: 9568614

Therapeutic indications

Esomeprazole is indicated for:

Healing of gastric ulcers associated with NSAID therapy

Population group: only adults (18 years old or older)

at least one of
Duodenal ulcer caused by non-steroidal anti-inflammatory drug
Drug induced gastric ulcer

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Erosive reflux esophagitis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Reflux esophagitis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Gastroesophageal reflux disease (GERD)

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Symptomatic treatment of gastroesophageal reflux disease (GERD).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of erosive reflux esophagitis relapse

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Long-term management of patients with healed esophagitis to prevent relapse.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prevention of relapse of peptic ulcers associated with Helicobacter pylori

Population group: only adults (18 years old or older)

In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori and prevention of relapse of peptic ulcers in patients with Helicobacter pylori associated ulcers.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prevention of gastric and duodenal ulcers associated with NSAID therapy

Population group: only adults (18 years old or older)

Prevention of gastric and duodenal ulcers associated with NSAID therapy in patients at risk.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Zollinger-Ellison syndrome

Population group: only adults (18 years old or older)

Zollinger-Ellison syndrome

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Eradication of Helicobacter pylori

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori and healing of Helicobacter pylori associated duodenal ulcer.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prevention of rebleeding following therapeutic endoscopy for acute bleeding gastric or duodenal ulcers

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

at least one of
Duodenal ulcer with hemorrhage
Gastric ulcer with hemorrhage

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prolonged therapy after intravenous treatment to prevent rebleeding of peptic ulcers

Population group: only adults (18 years old or older)

at least one of
Duodenal ulcer with hemorrhage
Gastric ulcer with hemorrhage

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Esomeprazole is contraindicated in the following cases:

Nelfinavir

Nelfinavir

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