The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | R | Respiratory system | |
| 2 | R03 | Drugs for obstructive airway diseases | |
| 3 | R03B | Other drugs for obstructive airway diseases, inhalants | |
| 4 | R03BB | Anticholinergics | |
| 5 | R03BB01 | Ipratropium bromide |
The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.
| Route | Amount |
|---|---|
| RESPIR - Respiratory (Inhalation) (aerosol) | 0.12 mg |
| RESPIR - Respiratory (Inhalation) (powder) | 0.12 mg |
| RESPIR - Respiratory (Inhalation) (solution) | 0.3 mg |
| Active Ingredient | Description | |
|---|---|---|
| Ipratropium |
Ipratropium is a quaternary ammonium compound with anticholinergic (parasympatholytic) properties. Ipratropium appears to inhibit vagally mediated reflexes by antagonising the action of acetylcholine, the transmitter agent released from the vagus nerve. Anticholinergics prevent the increase in intracellular concentration of Ca++, which is caused by interaction of acetylcholine with the muscarinic receptor on bronchial smooth muscle. Ca++ release is mediated by the second messenger system consisting of IP3 (inositol triphosphate) and DAG (diacylglycerol). |
| Title | Information Source | Document Type | |
|---|---|---|---|
| ATROVENT HFA Inhalation aerosol, metered | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| ATROVENT Nebuliser solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
