Source: Web Search Revision Year: 2012 Publisher: Manufacturer: S.C. Europharm S.A., 2 Panselelor str., Brasov, county of Brasov, 500419, Romania Marketing authorization holder: GlaxoSmithKline Consumer Healthcare, United Kingdom, 980 Great West Road, Brentford, Middlesex, TW8 9GS
Coldrex Tablets.
| Pharmaceutical Form |
|---|
|
Tablet. |
Each tablet contains Paracetamol Ph.Eur. 500.0mg, Caffeine Ph.Eur. 25.0mg, Phenylephrine hydrochloride Ph Eur 5 mg, Terpin Hydrate BPC 20 mg, Ascorbic Acid 30 mg.
| Active Ingredient |
|---|
|
Caffeine is structurally related to the methylxanthines theophylline and theobromine. Caffeine's main action is as a CNS stimulant. |
|
Paracetamol is a medication used to treat pain and fever. It does appear to selectively inhibit COX activities in the brain, which may contribute to its ability to treat fever and pain. |
|
Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system. The sympathomimetic effect of phenylephrine produces vasoconstriction which in turn relieves nasal congestion. |
|
Ascorbic acid, coupled with dehydroascorbic acid to which it is reversibly oxidised, has a variety of functions in cellular oxidation processes. Ascorbic acid is required in several important hydroxylations, including the conversion of proline to hydroxyproline and appears to have an important role in metal ion metabolism, including the gastrointestinal absorption of iron and its transport between plasma and storage organs. |
| List of Excipients |
|---|
|
Maize starch |
Tablets. 12 tablets in blister (PVC/aluminum foil). One blister is packed in one cardboard cartons with patient information leaflet.
Manufacturer: S.C. Europharm S.A., 2 Panselelor str., Brasov, county of Brasov, 500419, Romania
Marketing authorization holder: GlaxoSmithKline Consumer Healthcare, United Kingdom, 980 Great West Road, Brentford, Middlesex, TW8 9GS
PL 00071/5005R
23/02/2011
| Drug | Countries | |
|---|---|---|
| COLDREX | Estonia, Hong Kong, Croatia, Lithuania, Poland |
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