MENOGRAINE Film-coated tablet Ref.[115281] Active ingredients: Clonidine

Source: Health Products Regulatory Authority (ZA)  Revision Year: 2022  Publisher: PHARMACARE LIMITED, Healthcare Park, Woodlands Drive, Woodmead 2191

Product name and form

MENOGRAINE tablet.

Pharmaceutical Form

Tablets.

MENOGRAINE is a blue, round-shaped biconvex film-coated tablet, debossed with “12” on one side and plain on the other side.

Qualitative and quantitative composition

Each tablet of MENOGRAINE contains 25 μg of clonidine hydrochloride.

Contains sugar: Lactose monohydrate 30,118 mg.

For full list of excipients, see section 6.1.

Active Ingredient

Clonidine has been shown to have both central and peripheral sites of action. With long-term treatment clonidine reduces the responsiveness of peripheral vessels to vasoconstrictor and vasodilator substances and to sympathetic nerve stimulation. Early in treatment, however, blood pressure reduction is associated with a central reduction of sympathetic outflow and increased vagal tone.

List of Excipients

Lactose monohydrate
Magnesium stearate
Microcrystalline cellulose
Opadry 04B505004 Blue (hypromellose, indigo carmine aluminium lake, macrogol 400, titanium dioxide)
Sodium starch glycollate
Starch maize
Purified talc

Pack sizes and marketing

Packs of 30 and 100 tablets in white polypropylene securitainers sealed together with a package insert, foam insert or rayon, using a round white, flat-topped low-density polyethylene (LDPE) closure.

Packs of 30 and 100 tablets in white, opaque, round high-density polyethylene (HDPE) containers, sealed together with white absorbent cotton using a white, opaque polypropylene fine-ribbed screw cap.

Packs of 20 tablets in polyvinyl chloride (PVC) blister strips sealed using aluminium foil. The blister strips are packed together with a package insert, into pre-printed cardboard unit cartons.

Not all packs and pack sizes are necessarily marketed.

Marketing authorization holder

PHARMACARE LIMITED, Healthcare Park, Woodlands Drive, Woodmead 2191

Marketing authorization dates and numbers

M/7.3/41

04 April 1986

Drugs

Drug Countries
MENOGRAINE South Africa

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