MENOGRAINE Film-coated tablet Ref.[115281] Active ingredients: Clonidine

Posology

Adults

Take one tablet morning and night, increasing to three tablets twice daily if necessary.

Method of administration

For oral administration.

The coated tablet should not be chewed because of bad taste.

Symptoms

Symptoms of overdosage are due to a generalised sympathetic depression and include pupillary constriction, somnolence including coma, transient hypertension, bradycardia, hypothermia, sedation, miosis, respiratory depression including apnoea, convulsions, occasionally vomiting and dryness of the mouth.

Treatment

Treatment is supportive and symptomatic. An alpha adreno-receptor blocking medicine may be given if necessary.

Administration of activated charcoal should be performed where appropriate. Supportive care may include atropine sulfate for symptomatic bradycardia, and intravenous fluids and/or inotropic sympathomimetic medicines for hypotension. Severe persistent hypertension may require correction with alpha-adrenoceptor blocking medicines.

Naloxone may be a useful adjunct for the management of clonidine-induced respiratory depression.

24 months.

Store at or below 25°C.

Keep container tightly closed.

Protect from light.

Keep in original packaging until required for use.

Packs of 30 and 100 tablets in white polypropylene securitainers sealed together with a package insert, foam insert or rayon, using a round white, flat-topped low-density polyethylene (LDPE) closure.

Packs of 30 and 100 tablets in white, opaque, round high-density polyethylene (HDPE) containers, sealed together with white absorbent cotton using a white, opaque polypropylene fine-ribbed screw cap.

Packs of 20 tablets in polyvinyl chloride (PVC) blister strips sealed using aluminium foil. The blister strips are packed together with a package insert, into pre-printed cardboard unit cartons.

Not all packs and pack sizes are necessarily marketed.

No special requirements.