Source: Registered Drug Product Database (NG) Publisher: Applicant (MAH): ORANGE DRUGS LIMITED, 66/68 Town Planning Way, Ilupeju, Lagos, Nigeria, Phone.: +2348036005454, Email: eojukwu@orangegroups.com Manufactured by: PT. Dankos Farma, Jl. Rawa Gatel Blok III S, Kav. 36-38, Kawasan Industri Pulo Gadung, Jakarta 13930 - Indonesia
To reduce and relieve the symptoms of headache, dizziness, fever, toothache, pain during menstruation, muscle pain and joint ache.
Information of medicine:
Pharmacology:
Act as analgesic for acute painful and antipyretic. Caffeine enhances the analgesic efficacy of acetaminophen.
For oral administration.
Adults: 1-2 caplets, 3-4 times daily.
Liver damage is possible in adults who have taken 10g or more of paracetamol. Ingestion of 5g or more of paracetamol may lead to liver damage if the patient has risk factors (see below).
If the patient
a) Is on long term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John's Wort or other drugs that induce liver enzymes or
b) Regularly consumes ethanol in excess of recommended amounts or
c) Is likely to be glutathione deplete e.g. eating disorders, cystic fibrosis, HIV infection, starvation, cachexia Symptoms of paracetamol overdosage in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur. In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral odema and death. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage. Cardiac arrhythmias and pancreatitis have been reported.
Immediate treatment is essential in the management of paracetamol overdose. Despite a lack of significant early symptoms, patients should be referred to hospital urgently for immediate medical attention. Symptoms may be limited to nausea or vomiting and may not reflect the severity of the overdose or the risk of organ damage. Management should be in accordance with established treatment guidelines, see BNF overdose section. Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable) but results should not delay initiation of treatment beyond 8 hours after ingestion, as the effectiveness of the antidote declines sharply after this time. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside of hospital.
60 months.
Protect from light. Store below 30°C.
Keep all medicines out of reach of children.
Primary packaging: Polycellonium foil strip.
Secondary packaging: Catch cover: Artpaper 85 g/m². Box: Duplex coated 270 g/m² + Water Based. Packing : Box, 25 Catch cover @ 1 strip @ 4 caplets (envelope containing 4 caplets in alumunium strip).
None.
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.