Betamethasone
Chemical formula: C₂₂H₂₉FO₅ Molecular mass: 392.461 g/mol PubChem compound: 9782
Active ingredient description
Betamethasone is a glucocorticoid which is about eight to ten times as active as prednisolone on a weight-for-weight basis. Betamethasone has anti-inflammatory, antipruritic, and vasoconstrictive properties.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| A07EA04 | Betamethasone | A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07E Intestinal antiinflammatory agents → A07EA Corticosteroids acting locally |
| C05AA05 | Betamethasone | C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AA Corticosteroids |
| D07AC01 | Betamethasone | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AC Corticosteroids, potent (group III) |
| D07XC01 | Betamethasone | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07X Corticosteroids, other combinations → D07XC Corticosteroids, potent, other combinations |
| H02AB01 | Betamethasone | H Systemic hormonal preparations, excl. Sex hormones and insulins → H02 Corticosteroids for systemic use → H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN → H02AB Glucocorticoids |
| R01AD06 | Betamethasone | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AD Corticosteroids |
| R03BA04 | Betamethasone | R Respiratory system → R03 Drugs for obstructive airway diseases → R03B Other drugs for obstructive airway diseases, inhalants → R03BA Glucocorticoids |
| S01BA06 | Betamethasone | S Sensory organs → S01 Ophthalmologicals → S01B Antiinflammatory agents → S01BA Corticosteroids, plain |
| S01CB04 | Betamethasone | S Sensory organs → S01 Ophthalmologicals → S01C Antiinflammatory agents and antiinfectives in combination → S01CB Corticosteroids/antiinfectives/mydriatics in combination |
| S02BA07 | Betamethasone | S Sensory organs → S02 Otologicals → S02B Corticosteroids → S02BA Corticosteroids |
| S03BA03 | Betamethasone | S Sensory organs → S03 Ophthalmological and otological preparations → S03B Corticosteroids → S03BA Corticosteroids |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| BETNOVATE Lotion | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| BETNESOL Solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| Betnovate Cream | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| DIPROLENE AF Cream | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
Medicines
Betamethasone is an active ingredient of these brands:
Albania (AL)
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)
Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
United States (US)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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