Mometasone

Chemical formula: C₂₇H₃₀Cl₂O₆  Molecular mass: 427.361 g/mol  PubChem compound: 441335

Active ingredient description

Mometasone is a topical glucocorticoid with local anti-inflammatory properties. It is likely that much of the mechanism for the effects of mometasone lies in its ability to inhibit the release of mediators of the inflammatory cascade.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D07AC13 Mometasone D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AC Corticosteroids, potent (group III)
Discover more medicines within D07AC13
D07XC03 Mometasone D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07X Corticosteroids, other combinations → D07XC Corticosteroids, potent, other combinations
Discover more medicines within D07XC03
R01AD09 Mometasone R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AD Corticosteroids
Discover more medicines within R01AD09
R03BA07 Mometasone R Respiratory system → R03 Drugs for obstructive airway diseases → R03B Other drugs for obstructive airway diseases, inhalants → R03BA Glucocorticoids
Discover more medicines within R03BA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MOMETASONE FUROATE Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ELOCON Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
NASONEX Nasal spray FDA, National Drug Code (US) MPI, US: SPL/PLR
NASONEX Nasal Spray, Suspension Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ELOCON Cream, 0.1% FDA, National Drug Code (US) MPI, US: SPL/PLR
ELOCON Lotion, 0.1% FDA, National Drug Code (US) MPI, US: SPL/PLR
ASMANEX TWISTHALER Inhalation powder Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 105102-22-5
CAS Substance: 83919-23-7
DrugBank Drug: DB00764
KEGG Drug: D08227
PubChem Compound: 441335
RxNorm Ingredient: 108118
SNOMED-CT Concept: 395990009
Mometasone (substance)
UNII Identifier: 8HR4QJ6DW8
MOMETASONE

Medicines

Mometasone is an active ingredient of these brands:

United States (US)

  • ASMANEX as MOMETASONE FUROATE
  • ELOCON as MOMETASONE FUROATE
  • NASONEX as MOMETASONE FUROATE MONOHYDRATE
  • SINUVA as MOMETASONE FUROATE

  • (combination) DULERA as MOMETASONE FUROATE

Australia (AU)

Austria (AT)

Brazil (BR)

  • AMOME as MOMETASONE FUROATE MONOHYDRATE
  • MOMATE as MOMETASONE FUROATE MONOHYDRATE
  • NASONEX as MOMETASONE FUROATE MONOHYDRATE
  • NITES as MOMETASONE FUROATE
  • OXIMAX as MOMETASONE FUROATE
  • RESGAT as MOMETASONE FUROATE
  • TOPISON as MOMETASONE FUROATE

  • (combination) DERMOTIL FUSID as MOMETASONE FUROATE

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

  • ASMANEX as MOMETASONE FUROATE
  • NASONEX as MOMETASONE FUROATE MONOHYDRATE

  • (combination) ENERZAIR as MOMETASONE FUROATE

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

  • ELOCOM as MOMETASONE FUROATE

  • (combination) ENERZAIR as MOMETASONE FUROATE
  • (combination) RYALTRIS as MOMETASONE FUROATE

Italy (IT)

  • (combination) ENERZAIR as MOMETASONE FUROATE
  • (combination) ZIMBUS as MOMETASONE FUROATE

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

  • ASMANEX as MOMETASONE FUROATE
  • ELOMET as MOMETASONE FUROATE
  • ELOSONE as MOMETASONE FUROATE
  • MELOMET as MOMETASONE FUROATE
  • MOMENSA as MOMETASONE FUROATE MONOHYDRATE
  • NASONEX as MOMETASONE FUROATE MONOHYDRATE
  • VIZOMET as MOMETASONE FUROATE

  • (combination) ELOSALIC as MOMETASONE FUROATE
  • (combination) ZENHALE as MOMETASONE FUROATE

South Africa (ZA)

Spain (ES)

  • ASMANEX as MOMETASONE FUROATE
  • ELOCOM as MOMETASONE FUROATE
  • KONEX as MOMETASONE FUROATE
  • NASOALDO as MOMETASONE FUROATE
  • NASONEX as MOMETASONE FUROATE MONOHYDRATE

  • (combination) ZIMBUS as MOMETASONE FUROATE

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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