ATC Group: D07AD Corticosteroids, very potent (group IV)

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of D07AD in the ATC hierarchy

Level Code Title
1 D Dermatologicals
2 D07 Corticosteroids, dermatological preparations
3 D07A Corticosteroids, plain
4 D07AD Corticosteroids, very potent (group IV)

Group D07AD contents

Code Title
D07AD01 Clobetasol
D07AD02 Halcinonide

Active ingredients in D07AD

Active Ingredient Description
Clobetasol propionate

Clobetasol propionate, like other topical corticosteroids, has anti-inflammatory, antipruritic, and vasoconstrictive properties. Corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid.

Halcinonide

Halcinonide is a topical corticosteroid. Topical corticosteroids share anti-inflammatory, antipruritic and vasoconstrictive actions. The mechanism of anti-inflammatory activity is unclear. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.

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