Chemical formula: C₂₂H₂₄N₂O₈ Molecular mass: 444.435 g/mol PubChem compound: 54675776
Tetracyclines are taken up into sensitive bacterial cells by an active transport process. Once within the cell they bind reversibly to the 30S subunit of the ribosome, preventing the binding of aminoacyl transfer RNA and inhibiting protein synthesis and hence cell growth.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A01AB13 | Tetracycline | A Alimentary tract and metabolism → A01 Stomatological preparations → A01A Stomatological preparations → A01AB Antiinfectives and antiseptics for local oral treatment |
| D06AA04 | Tetracycline | D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06A Antibiotics for topical use → D06AA Tetracycline and derivatives |
| J01AA07 | Tetracycline | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01A Tetracyclines → J01AA Tetracyclines |
| S01AA09 | Tetracycline | S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AA Antibiotics |
| S02AA08 | Tetracycline | S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives |
| S03AA02 | Tetracycline | S Sensory organs → S03 Ophthalmological and otological preparations → S03A Antiinfectives → S03AA Antiinfectives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| TETRACYCLINE Film-coated tablet | Marketing Authorisation Holder | MPI, EU: SmPC |
Tetracycline is an active ingredient of these brands:
United States (US)Austria (AT)
Brazil (BR)Cyprus (CY)
Ecuador (EC)
Finland (FI)
France (FR)
Hong Kong (HK)
Japan (JP)
Lithuania (LT)
Mexico (MX)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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