ATC Group: J01AA Tetracyclines

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of J01AA in the ATC hierarchy

Level Code Title
1 J Antiinfectives for systemic use
2 J01 Antibacterials for systemic use
3 J01A Tetracyclines
4 J01AA Tetracyclines

Group J01AA contents

Code Title
J01AA01 Demeclocycline
J01AA02 Doxycycline
J01AA03 Chlortetracycline
J01AA04 Lymecycline
J01AA05 Metacycline
J01AA06 Oxytetracycline
J01AA07 Tetracycline
J01AA08 Minocycline
J01AA09 Rolitetracycline
J01AA10 Penimepicycline
J01AA11 Clomocycline
J01AA12 Tigecycline
J01AA13
J01AA14
J01AA15
J01AA20 Combinations of tetracyclines
J01AA56 Oxytetracycline, combinations

Active ingredients in J01AA

Active Ingredient Description
Chlortetracycline

Chlortetracycline is a tetracycline antibiotic isolated from Streptomyces aureofaciens. It has a role as an antiprotozoal drug, a fluorescent probe, a calcium ionophore and an antibacterial drug.

Clomocycline
Demeclocycline

Tetracyclines have a broad spectrum of anti-microbial activity and act by interfering with bacterial protein synthesis. They are active against a large number of gram positive and gram negative pathogenic bacteria, including some which are resistant to penicillin.

Doxycycline

Doxycycline is primarily bacteriostatic and is believed to exert its antimicrobial effect by the inhibition of protein synthesis.

Metacycline
Minocycline

Minocycline is a semi-synthetic derivative of tetracycline. Minocycline inhibits protein synthesis in susceptible bacteria. In common with other tetracyclines it is primarily bacteriostatic and has a similar spectrum of activity to other tetracyclines.

Omadacycline

Omadacycline is an antibacterial drug. It should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

Oxytetracycline

Oxytetracycline is a broad spectrum tetracycline antibiotic with activity against a large number of gram positive and gram negative bacteria. The product acts by interfering with bacterial protein synthesis.

Rolitetracycline
Sarecycline

Sarecycline is a narrow-spectrum tetracycline-class antibiotic indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 9 years of age and older.

Tetracycline

Tetracyclines are taken up into sensitive bacterial cells by an active transport process. Once within the cell they bind reversibly to the 30S subunit of the ribosome, preventing the binding of aminoacyl transfer RNA and inhibiting protein synthesis and hence cell growth.

Tigecycline

Tigecycline, a glycylcycline antibiotic, inhibits protein translation in bacteria by binding to the 30S ribosomal subunit and blocking entry of amino-acyl tRNA molecules into the A site of the ribosome. This prevents incorporation of amino acid residues into elongating peptide chains.

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