Hydrocortisone Other names: Cortisol
Chemical formula: C₂₁H₃₀O₅ Molecular mass: 362.46 g/mol PubChem compound: 5754
Active ingredient description
Hydrocortisone is the main glucocorticoid secreted by the adrenal cortex. Hydrocortisone is an anti-inflammatory steroid. Its anti-inflammatory action is due to reduction in the vascular component of the inflammatory response and reduction in the formation of inflammatory fluid and cellular exudates.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| A01AC03 | Hydrocortisone | A Alimentary tract and metabolism → A01 Stomatological preparations → A01A Stomatological preparations → A01AC Corticosteroids for local oral treatment |
| A07EA02 | Hydrocortisone | A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07E Intestinal antiinflammatory agents → A07EA Corticosteroids acting locally |
| C05AA01 | Hydrocortisone | C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AA Corticosteroids |
| D07AA02 | Hydrocortisone | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AA Corticosteroids, weak (group I) |
| D07AB11 | Hydrocortisone buteprate | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AB Corticosteroids, moderately potent (group II) |
| D07AC16 | Hydrocortisone aceponate | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AC Corticosteroids, potent (group III) |
| D07XA01 | Hydrocortisone | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07X Corticosteroids, other combinations → D07XA Corticosteroids, weak, other combinations |
| H02AB09 | Hydrocortisone | H Systemic hormonal preparations, excl. Sex hormones and insulins → H02 Corticosteroids for systemic use → H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN → H02AB Glucocorticoids |
| S01BA02 | Hydrocortisone | S Sensory organs → S01 Ophthalmologicals → S01B Antiinflammatory agents → S01BA Corticosteroids, plain |
| S01CB03 | Hydrocortisone | S Sensory organs → S01 Ophthalmologicals → S01C Antiinflammatory agents and antiinfectives in combination → S01CB Corticosteroids/antiinfectives/mydriatics in combination |
| S02BA01 | Hydrocortisone | S Sensory organs → S02 Otologicals → S02B Corticosteroids → S02BA Corticosteroids |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| ALKINDI Granule in capsule | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| HYDROCORTISONE Cream | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| HYDROCORTISONE 1% w/w Ointment | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| CORTEF Tablet | MPI, US: SPL/Old | FDA, National Drug Code (US) | |
| HYDROCORTISONE Tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| HYDROCORTISONE Solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| CORTENEMA Enema | MPI, US: SPL/Old | FDA, National Drug Code (US) |
Structural formula
3D molecular structure
External identifiers
Medicines
Hydrocortisone is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
United States (US)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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