Indications A-Z

RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.

This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Indications starting with 'N'

Indication	Treatments
Narcolepsy	Solriamfetol : Narcolepsy – only adults (18 years old or older)
Nasal congestion	Ephedrine : Nasal congestion – only adolescents (12 years - 18 years old) , adults (18 years old or older) Oxymetazoline : Nasal congestion – only children (1 year - 12 years old) Oxymetazoline : Nasal congestion – only adolescents (12 years - 18 years old) , adults (18 years old or older) Phenylephrine : Nasal congestion – only adults (18 - 65 years old) Pseudoephedrine : Nasal congestion, sinus congestion – only adolescents (12 years - 18 years old) , adults (18 years old or older) Xylometazoline : Nasal congestion – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Nasopharyngeal carcinoma	Toripalimab : Nasopharyngeal carcinoma - first-line treatment – only adults (18 years old or older) Toripalimab : Recurrent unresectable or metastatic nasopharyngeal carcinoma – only adults (18 years old or older)
Nausea	Dimenhydrinate : Nausea, vertigo – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Dimenhydrinate : Nausea, vertigo – only adolescents (12 years - 18 years old) , adults (18 years old or older) Itopride : Functional, non-ulcer dyspepsia, bloating, gastric fullness, discomfort to pain in epigastrium, anorexia, heartburn, nausea – only adults (18 years old or older) Promethazine : Nausea, vomiting – only adults (18 years old or older)
Nausea and vomiting	Chlorpromazine : Nausea, vomiting – only elderly (65 years old or older) Chlorpromazine : Nausea, vomiting – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Chlorpromazine : Nausea, vomiting – only adults (18 - 65 years old) Domperidone : Nausea and vomiting – only adolescents (12 years - 18 years old) , adults (18 years old or older) Domperidone : Nausea and vomiting – only children (1 year - 12 years old) Metoclopramide : Symptomatic treatment of nausea and vomiting – only adults (18 years old or older) Perphenazine : Nausea, vomiting – only adults (18 - 65 years old) Trifluoperazine : Psychoses, mental subnormality, nausea and vomiting – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Necatoriasis caused by Necator americanus	Mebendazole : Whipworm, pinworm, threadworm, roundworm, common hookworm, American hookworm – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Neck pain	Paracetamol : Pain, fever – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Necrotising respiratory granulomatosis	Avacopan : Granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) – only adults (18 years old or older) Cyclophosphamide : Wegener's granulomatosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Rituximab : Granulomatosis with polyangiitis and microscopic polyangiitis – only adults (18 years old or older)
Neonatal diabetes mellitus	Glibenclamide : Neonatal diabetes mellitus – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Neonatal hypocalcemic tetany	Calcium gluconate : Neonatal tetany – only newborns (0 - 40 days old)
Neoplasm of esophagus	Nivolumab : Gastric, gastro-oesophageal junction (GEJ) or oesophageal adenocarcinoma – only adults (18 years old or older)
Neoplasm of islets of Langerhans	Octreotide : Gastro-entero-pancreatic endocrine tumours – only adults (18 years old or older) Sunitinib : Pancreatic neuroendocrine tumours (pNET) – only adults (18 years old or older)
Nephroblastoma	22-Oxovincaleukoblastine : Wilms' tumour – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Nephrotic syndrome	Chlortalidone : Ascites due to cirrhosis, oedema due to nephrotic syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Chlortalidone : Ascites due to cirrhosis, oedema due to nephrotic syndrome – only adults (18 years old or older) Ciclosporin : Nephrotic syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Spironolactone : Nephrotic syndrome – only adults (18 years old or older)
Nettle sting	Mepyramine : Insect stings, insect bites, nettle stings – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Neuralgia	Ibuprofen : Neuralgia – only adolescents (12 years - 18 years old) , adults (18 years old or older) Paracetamol : Pain, fever – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Neuroblastoma	22-Oxovincaleukoblastine : Neuroblastoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Cyclophosphamide : Advanced or metastatic neuroblastoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Dinutuximab : Neuroblastoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old) Melphalan : Advanced neuroblastoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Naxitamab : Neuroblastoma in the bone or bone marrow – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Neurocirculatory asthenia	Oxprenolol : Cardiac neurosis, hyperkinetic heart syndrome, anxiety induced cardiovascular disorders – only adults (18 years old or older)
Neuroendocrine neoplasm of gastrointestinal tract	Everolimus : Neuroendocrine tumours of gastrointestinal or lung origin – only adults (18 years old or older) Lanreotide : Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) – only adults (18 years old or older)
Neuroendocrine tumor of pancreas	Everolimus : Neuroendocrine tumours of pancreatic origin – only adults (18 years old or older) Lanreotide : Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) – only adults (18 years old or older)
Neuroendocrine tumour	Lanreotide : Neuroendocrine tumours – only adults (18 years old or older)
Neurofibromatosis type 1	Selumetinib : Neurofibromatosis type 1 (NF1) with plexiform neurofibromas (PN) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Neurogenic detrusor overactivity	Mirabegron : Neurogenic detrusor overactivity – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Propiverine : Overactive bladder syndrome, neurogenic detrusor overactivity – only adults (18 years old or older) Solifenacin : Neurogenic detrusor overactivity – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Neurohypophyseal diabetes insipidus	Desmopressin : Cranial diabetes insipidus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old) Desmopressin : Cranial diabetes insipidus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Neuromyelitis optica	Eculizumab : Neuromyelitis optica spectrum disorder (NMOSD) – only adults (18 years old or older) Inebilizumab : Neuromyelitis optica spectrum disorders, anti-aquaporin-4 immunoglobulin G seropositive patients – only adults (18 years old or older) Ravulizumab : Neuromyelitis optica spectrum disorder – only adults (18 years old or older) Satralizumab : Neuromyelitis optica spectrum disorder (NMOSD) – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Neuronal ceroid lipofuscinosis	Cerliponase alfa : Neuronal ceroid lipofuscinosis type 2 (CLN2) disease, tripeptidyl peptidase 1 (TPP1) deficiency – only minors (0 - 18 years old) Cerliponase alfa : Neuronal ceroid lipofuscinosis type 2 (CLN2) disease, tripeptidyl peptidase 1 (TPP1) deficiency – only adults (18 - 65 years old)
Neuropathic pain	Pregabalin : Neuropathic pain – only adults (18 years old or older)
Neuropathy caused by isoniazid	Pyridoxine : Isoniazid-induced peripheral neuritis – only adults (18 years old or older)
Neurotrophic keratitis	Cenegermin : Neurotrophic keratitis – only adults (18 years old or older)
Neutropaenia due to and following chemotherapy	Efbemalenograstim alfa : Neutropenia due to cytotoxic chemotherapy for malignancy – only adults (18 years old or older) Lenograstim : Severe neutropenia in cytotoxic therapy – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Lipegfilgrastim : Neutropenia after cytotoxic chemotherapy for malignancy – only adults (18 years old or older)
Nicholas Favre disease	Doxycycline : Chancroid, granuloma inguinale, lymphogranuloma venereum – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Nicotine poisoning	Biperiden : Nicotine poisoning
Nicotine withdrawal	Nicotine : Tobacco dependence, nicotine withdrawal symptoms, smoking cessation – only adults (18 years old or older)
Niemann-Pick disease, type A	Olipudase alfa : Acid Sphingomyelinase Deficiency (ASMD) in patients with type A/B or type B – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Olipudase alfa : Acid Sphingomyelinase Deficiency (ASMD) in patients with type A/B or type B – only adults (18 years old or older)
Niemann-Pick disease, type B	Olipudase alfa : Acid Sphingomyelinase Deficiency (ASMD) in patients with type A/B or type B – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Olipudase alfa : Acid Sphingomyelinase Deficiency (ASMD) in patients with type A/B or type B – only adults (18 years old or older)
Niemann-Pick disease, type C	Miglustat : Niemann-Pick type C disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Night cramps	Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older) Quinine : Treatment and prevention of nocturnal leg cramps – only adults (18 years old or older)
NM - Neuromuscular blockade observation	Neostigmine : Antagonist to non-depolarizing neuromuscular blockade – only minors (0 - 18 years old) , adults (18 years old or older)
Nocardiosis	Minocycline : Nocardiosis – only adolescents (12 years - 18 years old) Minocycline : Nocardiosis – only adults (18 years old or older)
Nodal tachycardia	Amiodarone : Tachyarrhythmias – only adults (18 years old or older)
Non dystrophic myotonia	Mexiletine : Myotonia in non-dystrophic myotonic disorders – only adults (18 years old or older)
Non-bullous impetigo	Ozenoxacin : Non-bullous impetigo – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Non-Hodgkin's lymphoma (clinical)	Bendamustine : Non-Hodgkin's lymphomas – only adolescents (12 years - 18 years old) , adults (18 years old or older) Bleomycin : Non-Hodgkin's lymphoma – only adults (18 years old or older) Carmustine : Non-Hodgkin's lymphoma, Hodgkin's disease – only adults (18 years old or older) Chlorambucil : Μη Hodgkin λέμφωμα – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Cyclophosphamide : Non-Hodgkin's lymphoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Etoposide : Non-Hodgkin's lymphoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Etoposide : Non-Hodgkin's lymphoma – only adults (18 years old or older) Mitoxantrone : Non-Hodgkin's lymphoma – only adults (18 years old or older)
Non-infectious anterior uveitis	Dexamethasone : Non-infectious uveitis – only adults (18 years old or older)
Non-Q wave myocardial infarction	Dalteparin : Unstable angina, non-Q wave myocardial infarction – only adults (18 years old or older) Eptifibatide : Unstable angina, non-Q-wave myocardial infarction – only adults (18 years old or older) Nadroparin : Unstable angina, non-Q wave myocardial infarction – only adults (18 years old or older) Tirofiban : Acute coronary syndromes without ST elevation (NSTE-ACS) – only adults (18 years old or older)
Non-small cell lung cancer	Adagrasib : Advanced non-small cell lung cancer with KRAS G12C mutation – only adults (18 years old or older) Atezolizumab : Non-small cell lung cancer, second-line treatment – only adults (18 years old or older) Atezolizumab : Platinum-ineligible non-small cell lung cancer – only adults (18 years old or older) Binimetinib : Non-small cell lung cancer with a BRAF V600E mutation – only adults (18 years old or older) Capmatinib : Non-small cell lung cancer (NSCLC) – only adults (18 years old or older) Cemiplimab : Non-small cell lung cancer with PD-L1 ≥50% – only adults (18 years old or older) Cemiplimab : Non-small cell lung cancer with PD-L1 ≥50% – only adults (18 years old or older) Cis-Diaminedichloroplatinum : Non-small cell lung cancer – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Docetaxel : Non-small cell lung cancer – only adults (18 years old or older) Durvalumab : Locally advanced non-small cell lung cancer with PD-L1 ≥1% – only adults (18 years old or older) Encorafenib : Advanced non-small cell lung cancer with a BRAF V600E mutation – only adults (18 years old or older) Gemcitabine : Non-small cell lung cancer (NSCLC) – only adults (18 years old or older) Mitomycin : Non-small cell bronchial carcinoma – only adults (18 years old or older) Nivolumab : Neoadjuvant treatment of non-small cell lung cancer – only adults (18 years old or older) Nivolumab : Non-small cell lung cancer – only adults (18 years old or older) Nivolumab : Non-small cell lung cancer - combination treatment with ipilimumab and chemotherapy – only adults (18 years old or older) Pembrolizumab : Non-small cell lung carcinoma at high risk of recurrence following complete resection and chemotherapy – only adults (18 years old or older) Pembrolizumab : Resectable non-small cell lung carcinoma at high risk of recurrence – only adults (18 years old or older) Pemetrexed : Non-small cell lung cancer – only adults (18 years old or older) Pralsetinib : Advanced non-small cell lung cancer (NSCLC), RET fusion positive – only adults (18 years old or older) Ramucirumab : Non-small cell lung cancer – only adults (18 years old or older) Selpercatinib : RET fusion-positive non-small cell lung cancer – only adults (18 years old or older) Sotorasib : Non-small cell lung cancer (NSCLC) with KRAS G12C – only adults (18 years old or older) Sugemalimab : Non-small-cell lung cancer – only adults (18 years old or older) Tepotinib : Non-small cell lung cancer (NSCLC) harbouring alterations leading to METmex14 skipping – only adults (18 years old or older) Tislelizumab : Non-small cell lung cancer, combination therapy – only adults (18 years old or older) Tislelizumab : Non-small cell lung cancer, monotherapy – only adults (18 years old or older) Trametinib : Non-small cell lung cancer with a BRAF V600 mutation – only adults (18 years old or older) Trastuzumab deruxtecan : Advanced non-small cell lung cancer with an activating HER2 (ERBB2) mutation – only adults (18 years old or older) Vinorelbine : Non small cell lung cancer – only adults (18 years old or older)
Non-small cell lung cancer with mutation in epidermal growth factor receptor	Erlotinib : Non-small cell lung cancer (NSCLC) with EGFR activating mutations – only adults (18 years old or older) Lazertinib : First-line treatment of advanced non-small cell lung cancer with EGFR mutations in combination with amivantamab – only adults (18 years old or older)
Non-small cell lung cancer without mutation in epidermal growth factor receptor	Pembrolizumab : First-line treatment of metastatic non-small cell lung carcinoma with PD-L1 ≥50%, with no EGFR or ALK positive mutations – only adults (18 years old or older)
Non-small cell lung cancer, negative for epidermal growth factor receptor expression	Atezolizumab : Early-stage non-small cell lung cancer, EGFR and ALK-negative – only adults (18 years old or older) Ipilimumab : Non-small cell lung cancer, without EGFR mutation or ALK translocation – only adults (18 years old or older)
Non-small cell lung cancer, positive for epidermal growth factor receptor expression	Afatinib : Non-small cell lung cancer (NSCLC) with activating EGFR mutation – only adults (18 years old or older) Amivantamab : Advanced non-small cell lung cancer with EGFR mutations – only adults (18 years old or older) Amivantamab : Advanced non-small cell lung cancer with EGFR mutations – only adults (18 years old or older) Amivantamab : Advanced non-small cell lung cancer with EGFR mutations - first-line treatment – only adults (18 years old or older) Bevacizumab : Non-small cell lung cancer with Epidermal Growth Factor Receptor (EGFR) activating mutations – only adults (18 years old or older) Dacomitinib : Non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR)-activating mutations – only adults (18 years old or older) Gefitinib : Non-small cell lung cancer (NSCLC) EGFR-TK positive – only adults (18 years old or older) Osimertinib : Adjuvant treatment after complete tumour resection in stage IB-IIIA non-small cell lung cancer – only adults (18 years old or older) Osimertinib : Combination treatment of non-small cell lung cancer with epidermal growth factor receptor mutations – only adults (18 years old or older) Osimertinib : Non-small cell lung cancer with activating epidermal growth factor receptor mutations – only adults (18 years old or older)
Non-tuberculous mycobacterial pneumonia	Rifabutin : Non-tuberculous mycobacterial pneumonia – only adults (18 years old or older)
Nonexudative age-related macular degeneration	Avacincaptad pegol : Geographic atrophy secondary to age-related macular degeneration – only elderly (65 years old or older)
Nongonococcal urethritis	Cefpodoxime : Uncomplicated gonorrhea in men and women, uncomplicated rectal gonococcal infections in women – only adolescents (12 years - 18 years old) , adults (18 years old or older) Sultamicillin : Non-complicated gonococcal infection – only adults (18 years old or older)
Nongonococcal urethritis caused by Ureaplasma urealyticum	Doxycycline : Nongonococcal urethritis caused by Ureaplasma urealyticum – only adults (18 years old or older) Tetracycline : Non-gonococcal urethritis caused by Ureaplasma urealyticum – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Noninfectious panuveitis	Ciclosporin : Endogenous uveitis – only adults (18 years old or older)
Nonseasonal allergic rhinitis	Budesonide : Seasonal and perennial allergic rhinitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Mequitazine : Hay fever, perennial rhinitis, urticaria, allergic pruritis, insect bites, stings – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Methylprednisolone : Perennial allergic rhinitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Methylprednisolone : Perennial allergic rhinitis – only adults (18 years old or older) Mizolastine : Seasonal allergic rhinoconjunctivitis (hay fever), perennial allergic rhinoconjunctivitis, urticaria – only adolescents (12 years - 18 years old) , adults (18 years old or older) Mometasone : Perennial allergic rhinitis – only children (1 year - 12 years old) Mometasone : Perennial allergic rhinitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Nonsquamous nonsmall cell neoplasm of lung	Atezolizumab : Nonsquamous nonsmall cell neoplasm of lung – only adults (18 years old or older) Bevacizumab : Non-small cell lung cancer – only adults (18 years old or older) Pembrolizumab : First-line treatment of metastatic non-squamous non-small cell lung carcinoma with no EGFR or ALK positive mutations – only adults (18 years old or older)
Nonulcer dyspepsia	Atropine : Non ulcer dyspepsia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Itopride : Functional, non-ulcer dyspepsia, bloating, gastric fullness, discomfort to pain in epigastrium, anorexia, heartburn, nausea – only adults (18 years old or older)
NSCLC (non-small cell lung cancer) adenocarcinoma type	Nintedanib : Non-small cell lung cancer adenocarcinoma (2nd line treatment) – only adults (18 years old or older)
Nummular eczema	Betamethasone : Discoid eczema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Fluocinonide : Discoid eczema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Discoid eczema – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

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