Indications A-Z

RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.

This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Indications starting with 'D'

Indication	Treatments
Decompensated cardiac failure	Dobutamine : Cardiac decompensation, disturbed ventricular function – only minors (0 - 18 years old) Dobutamine : Cardiac decompensation, disturbed ventricular function – only adults (18 years old or older)
Decompensated chronic heart failure	Levosimendan : Acutely decompensated chronic heart failure (ADHF) – only adults (18 years old or older)
Decreased carbohydrate	Glucose : Carbohydrate depletion, fluid depletion – only minors (0 - 18 years old) , adults (18 years old or older)
Deep mycosis	Posaconazole : Refractory invasive fungal infections (IFI) – only adults (18 years old or older)
Deep venous thrombosis	Bemiparin : Deep vein thrombosis – only adults (18 years old or older) Dabigatran : Deep vein thrombosis and pulmonary embolism – only adults (18 years old or older) Dabigatran : Recurrent deep vein thrombosis and pulmonary embolism – only adults (18 years old or older) Enoxaparin : Deep vein thrombosis (DVT), pulmonary embolism (PE) – only adults (18 years old or older) Heparin : Deep vein thrombosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Heparin : Deep vein thrombosis – only adults (18 years old or older) Nadroparin : Deep venous thrombosis, pulmonary embolism – only adults (18 years old or older) Rivaroxaban : Deep vein thrombosis (DVT), pulmonary embolism (PE) – only adults (18 years old or older)
Deficiency of mevalonate kinase	Canacinumab : Hyperimmunoglobulin D syndrome (HIDS), mevalonate kinase deficiency (MKD) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Deficiency of phosphoenolpyruvate kinase	Mitapivat : Pyruvate kinase deficiency (PK deficiency) – only adults (18 years old or older)
Deficiency of tryptophan decarboxylase	Eladocagene exuparvovec : Aromatic L-amino acid decarboxylase (AADC) deficiency with a severe phenotype – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Delayed puberty	Chorionic gonadotrophin (human) : Delayed puberty – men, only adolescents (12 years - 18 years old)
Deliberate self-harm	Lithium : Aggressive behaviour, self mutilating behaviour – only adults (18 years old or older)
Delirium	Haloperidol : Delirium – only elderly (65 years old or older) Haloperidol : Delirium – only adults (18 - 65 years old)
Delta-4-3-oxosteroid-5-beta-reductase deficiency	Cholic acid : Δ<sup>4</sup>-3-Oxosteroid-5β-reductase deficiency – only adults (18 - 65 years old)
Dementia associated with Parkinson's Disease	Rivastigmine : Mild to moderately severe dementia with idiopathic Parkinson's disease – only adults (18 years old or older)
Demodectic blepharitis	Lotilaner : Demodex blepharitis – only adults (18 years old or older)
Dental surgical procedure	Hexetidine : Mouth infections, gingivitis, sore throat, aphthous ulcer, halitosis, dental surgery – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Depressive disorder	Amoxapine : Relief of symptoms of depression – only adults (18 years old or older) Citalopram : Depression – only adults (18 - 65 years old) Citalopram : Depression – only elderly (65 years old or older) Clomipramine : Depressive illness – only adults (18 years old or older) Doxepin : Depression – only adults (18 years old or older) Maprotiline : Depression – only adults (18 years old or older) Trazodone : Depression – only elderly (65 years old or older) Trazodone : Depression – only adults (18 - 65 years old)
Dermabrasion	Dexpanthenol : Superficial skin lesion, skin inflammation
Dermal mycosis	Clotrimazole : Dermal mycosis
Dermatitis herpetiformis	Dapsone : Dermatitis herpetiformis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Dermatofibrosarcoma protuberans	Imatinib : Dermatofibrosarcoma protuberans (DFSP) – only adults (18 years old or older)
Dermatographic urticaria	Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Dermatomyositis	Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Dermatomyositis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prednisolone : Dermatomyositis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Dermatophytosis	Econazole : Dermatophytosis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Miconazole : Mycotic infections of the skin and nails – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Dermatosis of scalp	Clobetasol propionate : Recalcitrant dermatoses – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Diabetes insipidus	Chlortalidone : Diabetes insipidus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Chlortalidone : Diabetes insipidus – only adults (18 years old or older) Hydrochlorothiazide : Diabetes insipidus – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Diabetes mellitus	Insulin (human) : Diabetes mellitus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Insulin aspart : Diabetes mellitus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Insulin detemir : Diabetes mellitus – men, only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Insulin glargine : Diabetes mellitus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old) Insulin glulisine : Diabetes mellitus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Insulin icodec : Diabetes mellitus – only adults (18 years old or older) Insulin lispro : Diabetes mellitus – only adults (18 years old or older)
Diabetes mellitus type 2 in obese	Acarbose : Diabetes mellitus – only adults (18 years old or older) Rimonabant : Obese associated type 2 diabetes – only adults (18 years old or older)
Diabetes mellitus type I	Insulin degludec : Diabetes mellitus type 2 – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Teplizumab : Delay of the Stage 3 onset of type 1 diabetes – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Diabetes mellitus type II	Alogliptin : Diabetes mellitus type 2 – only adults (18 years old or older) Bexagliflozin : Diabetes mellitus type 2 – only adults (18 years old or older) Canagliflozin : Diabetes mellitus type 2 – only adults (18 years old or older) Dapagliflozin : Diabetes mellitus type 2 – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Dulaglutide : Type 2 diabetes mellitus – only adults (18 years old or older) Empagliflozin : Diabetes mellitus type 2 – only adults (18 years old or older) Ertugliflozin : Diabetes mellitus type 2 – only adults (18 years old or older) Exenatide : Diabetes mellitus type 2 – only adults (18 years old or older) Glibenclamide : Diabetes mellitus – only adults (18 years old or older) Gliclazide : Non insulin dependent diabetes mellitus type 2 – only adults (18 years old or older) Glimepiride : Diabetes mellitus type 2 – only adults (18 years old or older) Insulin degludec : Diabetes mellitus type 2 – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Liraglutide : Diabetes mellitus type 2 – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Lixisenatide : Diabetes mellitus type 2 – only adults (18 years old or older) Luseogliflozin : Diabetes mellitus type 2 – only adults (18 years old or older) Metformin : Type 2 diabetes mellitus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Nateglinide : Diabetes mellitus type 2 – only adults (18 - 65 years old) Pioglitazone : Diabetes mellitus type 2 – only adults (18 years old or older) Repaglinide : Diabetes mellitus type 2 – only adults (18 - 65 years old) Rosiglitazone : Diabetes mellitus type 2 – only adults (18 years old or older) Saxagliptin : Diabetes mellitus type 2 – only adults (18 years old or older) Semaglutide : Diabetes mellitus type 2 – only adults (18 years old or older) Semaglutide : Diabetes mellitus type 2 – only adults (18 years old or older) Sitagliptin : Diabetes mellitus type 2 – only adults (18 years old or older) Teneligliptin : Type 2 diabetes mellitus – only adults (18 years old or older) Tirzepatide : Insufficiently controlled type 2 diabetes mellitus – only adults (18 years old or older) Vildagliptin : Diabetes mellitus type 2 – only adults (18 years old or older)
Diabetic macular edema	Aflibercept : Visual impairment due to diabetic macular oedema (DME) – only adults (18 years old or older) Brolucizumab : Visual impairment due to diabetic macular oedema – only adults (18 years old or older) Dexamethasone : Diabetic macular edema (DME) – only adults (18 years old or older) Faricimab : Visual impairment due to diabetic macular oedema (DME) – only adults (18 years old or older)
Diabetic peripheral neuropathy	Duloxetine : Diabetic peripheral neuropathic pain – only adults (18 years old or older)
Diaper rash	Clobetasone : Atopic dermatitis, irritant or allergic contact dermatitis, seborrhoeic dermatitis, nappy rash, photodermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Hydrocortisone : Prurigo nodularis, neurodermatoses, otitis externa, intertrigo, napkin rash – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Diarrhea	Codeine : Diarrhoea – only adolescents (12 years - 18 years old) , adults (18 years old or older) Methylcellulose : Colostomy, ileostomy, diarrhoea – only adults (18 years old or older) Opium : Diarrhoea – only adults (18 - 65 years old)
Diffuse malignant lymphoma - histiocytic	Axicabtagene ciloleucel : Diffuse large B-cell lymphoma (DLBCL) – only adults (18 years old or older) Axicabtagene ciloleucel : Relapsed or refractory diffuse large B-cell lymphoma (DLBCL) – only adults (18 years old or older) Epcoritamab : Relapsed or refractory diffuse large B-cell lymphoma – only adults (18 years old or older) Glofitamab : Relapsed or refractory diffuse large B-cell lymphoma – only adults (18 years old or older) Lisocabtagene maraleucel : Relapsed or refractory diffuse large B-cell lymphoma (DLBCL) – only adults (18 years old or older) Loncastuximab tesirine : Diffuse large B-cell lymphoma (DLBCL), high-grade B-cell lymphoma (HGBL) – only adults (18 years old or older) Odronextamab : Relapsed or refractory diffuse large B-cell lymphoma – only adults (18 years old or older) Polatuzumab vedotin : Diffuse large B-cell lymphoma (DLBCL) – only adults (18 years old or older) Rituximab : Diffuse large B cell non-Hodgkin's lymphoma, CD20 positive – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Tafasitamab : Diffuse large B-cell lymphoma (DLBCL) – only adults (18 years old or older) Tisagenlecleucel : Relapsed or refractory diffuse large B-cell lymphoma – only adults (18 years old or older)
Diffuse spasm of esophagus	Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only children (1 year - 12 years old) Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Dilation of cervical canal	Mifepristone : Softening and dilatation of the cervix uteri prior to surgical termination of pregnancy during the first trimester – women, only adults (18 - 65 years old)
Diphtheria caused by Corynebacterium diphtheriae	Benzylpenicillin : Diphtheria – only newborns (0 - 40 days old) Benzylpenicillin : Diphtheria – only infants (40 days - 1 year old) , children (1 year - 12 years old) Benzylpenicillin : Diphtheria – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Direct current atrial defibrillation	Sotalol : Maintenance of normal sinus rhythm following conversion of atrial fibrillation or atrial flutter – only adults (18 years old or older)
Discoid lupus erythematosus	Betamethasone : Discoid lupus erythematosus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Fluocinonide : Discoid lupus erythematosus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Hydroxychloroquine : Juvenile idiopathic arthritis, discoid and systemic lupus erythematosus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Hydroxychloroquine : Rheumatoid arthritis, discoid and systemic lupus erythematosus, sunlight damaged skin – only adults (18 years old or older)
Disease caused by 2019 novel coronavirus	Bamlanivimab : Mild-to-moderate COVID-19 – only adolescents (12 years - 18 years old) Bamlanivimab : Mild-to-moderate COVID-19 – only adults (18 years old or older) Molnupiravir : Mild to moderate coronavirus disease 2019 (COVID-19) – only adults (18 - 65 years old) Regdanvimab : Coronavirus disease 2019 (COVID-19) – only adults (18 years old or older) Remdesivir : COVID-19 infection with an increased risk of progressing to severe COVID-19 – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Sotrovimab : Coronavirus disease 2019 (COVID-19) who do not require oxygen supplementation – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Disease caused by Ancylostomatoidea	Mebendazole : Whipworm, pinworm, threadworm, roundworm, common hookworm, American hookworm – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Disease caused by Gram-positive bacteria	Floxacillin : Infections – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Disinfection of skin	Ethanol : Disinfection of skin – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Disorder of musculoskeletal system	Naproxen : Musculoskeletal disorders – only adults (18 years old or older)
Disorder of the urea cycle metabolism	Glycerol phenylbutyrate : Urea cycle disorders (UCDs) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old) Sodium phenylbutyrate : Urea cycle disorders – only newborns (0 - 40 days old) , infants (40 days - 1 year old) Sodium phenylbutyrate : Urea cycle disorders – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Disorders of skin induced by physical agents	Dexpanthenol : Superficial skin lesion, skin inflammation
Dissection of aorta	Nicardipine : Malignant hypertension, hypertensive encephalopathy, dissection of aorta, postoperative hypertension – only elderly (65 years old or older) Nicardipine : Malignant hypertension, hypertensive encephalopathy, dissection of aorta, severe pre-eclampsia, postoperative hypertension – only adults (18 - 65 years old)
Disseminated candidiasis	Anidulafungin : Invasive candidiasis – only adults (18 years old or older) Caspofungin : Invasive candidiasis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) Caspofungin : Invasive candidiasis – only adults (18 years old or older) Fluconazole : Invasive candidiasis – only newborns (0 - 40 days old) Fluconazole : Invasive candidiasis – only infants (40 days - 1 year old) , children (1 year - 12 years old) Fluconazole : Invasive candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Micafungin : Invasive candidiasis – only newborns (0 - 40 days old) , infants (40 days - 1 year old) Micafungin : Invasive candidiasis – only children (1 year - 12 years old) Micafungin : Invasive candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Rezafungin : Invasive candidiasis – only adults (18 years old or older) Voriconazole : Invasive Candida infection – only children (1 year - 12 years old) Voriconazole : Invasive Candida infection – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Disseminated Lyme borreliosis	Ceftriaxone : Disseminated Lyme borreliosis (early [Stage II] and late [Stage III]) – only infants (40 days - 1 year old) , children (1 year - 12 years old) Ceftriaxone : Disseminated Lyme borreliosis (early [Stage II] and late [Stage III]) – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Disseminated tuberculosis	Methylprednisolone : Disseminated tuberculosis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) Methylprednisolone : Disseminated tuberculosis – only adults (18 years old or older)
Diverticular disease	Atropine : Diverticular disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Methylcellulose : Diverticular disease, ulcerative colitis – only adults (18 years old or older)
Doppler ultrasonography	Sulfur hexafluoride : Doppler sonography – only adults (18 years old or older)
Doppler ultrasonography of blood vessel	Sulfur hexafluoride : Doppler ultrasonography of blood vessel – only adults (18 years old or older)
Drug induced gastric ulcer	Esomeprazole : NSAID associated benign gastric and duodenal ulcers – only adults (18 years old or older) Lansoprazole : NSAID associated benign gastric and duodenal ulcers – only adults (18 years old or older) Omeprazole : Non-steroidal anti-inflammatory drug associated gastric and duodenal ulcers – only adults (18 years old or older) Ranitidine : Ulcers following NSAID therapy or associated with continued NSAIDs – only adults (18 years old or older)
Drug reaction	Promethazine : Allergic rhinitis, urticaria, anaphylactic reactions to drugs – only children (1 year - 12 years old) Promethazine : Allergic rhinitis, urticaria, anaphylactic reactions to drugs – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Drug treatment to delay menstruation	Norethisterone : Postponement of menstruation – women, only adults (18 - 65 years old)
Drug-aggravated angio-oedema-urticaria	Acetazolamide : Congestive heart failure oedema, drug induced oedema – only adults (18 years old or older)
Drug-induced hyperprolactinaemia	Bromocriptine : Drug-induced hyperprolactinaemic disorders – only adults (18 years old or older)
Drug-induced methemoglobinemia	Methylthioninium chloride : Drug induced methaemoglobinaemia – only newborns (0 - 40 days old) Methylthioninium chloride : Drug induced methaemoglobinaemia – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Drug-induced peptic ulcer	Misoprostol : Prophylaxis of NSAID-induced ulcers – only adults (18 years old or older)
Dry cornea	Hypromellose : Dehydration of the cornea and conjunctiva – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Dry cough	Butamirate : Dry cough – only adults (18 years old or older) Butamirate : Dry cough – only children (1 year - 12 years old) Butamirate : Dry cough – only adolescents (12 years - 18 years old) Codeine : Non-productive cough – only adults (18 years old or older) Dihydrocodeine : Non-productive cough – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Diphenhydramine : Non-productive cough – only adolescents (12 years - 18 years old) , adults (18 years old or older) Pholcodine : Non-productive, dry cough – only children (1 year - 12 years old)
Dry eyes	Acetylcysteine : Dry eyes Carbomer : Dry eye – only adults (18 years old or older) Carmellose : Dry eye – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Hypromellose : Dehydration of the cornea and conjunctiva – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Perfluorohexyloctane : Dry eye disease – only adults (18 years old or older) Polyvidone : Dry eye
Dry skin	Glycerol : Dry skin – only children (1 year - 12 years old) Glycerol : Dry skin – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Duchenne muscular dystrophy	Ataluren : Duchenne muscular dystrophy – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Delandistrogene moxeparvovec : Duchenne muscular dystrophy – only children (1 year - 12 years old) Givinostat : Duchenne muscular dystrophy – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old) Vamorolone : Duchenne muscular dystrophy – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Duodenal ulcer caused by Helicobacter pylori	Ranitidine : Duodenal ulcers associated with Helicobacter pylori infection – only adults (18 years old or older)
Duodenal ulcer caused by non-steroidal anti-inflammatory drug	Esomeprazole : NSAID associated benign gastric and duodenal ulcers – only adults (18 years old or older) Lansoprazole : NSAID associated benign gastric and duodenal ulcers – only adults (18 years old or older) Omeprazole : Non-steroidal anti-inflammatory drug associated gastric and duodenal ulcers – only adults (18 years old or older)
Duodenal ulcer disease	Cimetidine : Duodenal ulceration, gastric ulceration – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Cimetidine : Duodenal ulceration, gastric ulceration – only infants (40 days - 1 year old) Cimetidine : Duodenal ulceration, gastric ulceration – only adults (18 years old or older) Famotidine : Duodenal ulcer – only adults (18 years old or older) Lansoprazole : Duodenal ulcer – only adults (18 years old or older) Misoprostol : Duodenal ulcer, gastric ulcer – only adults (18 years old or older) Nizatidine : Duodenal ulcer – only adults (18 years old or older) Omeprazole : Duodenal ulcer – only adults (18 years old or older) Rabeprazole : Active duodenal ulcer, active benign gastric ulcer – only adults (18 years old or older) Ranitidine : Duodenal ulcer, benign gastric ulcer – only children (1 year - 12 years old) Ranitidine : Duodenal ulcer, benign gastric ulcer – only adolescents (12 years - 18 years old) , adults (18 years old or older) Sucralfate : Duodenal ulcer, chronic gastritis, peptic esophagitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Tripotassium dicitrato bismuthate : Gastric ulcer, duodenal ulcer – only adults (18 years old or older)
Dupuytren's disease of palm	Collagenase : Dupuytren's contracture – only adults (18 years old or older)
Dyslipidemia	Alirocumab : Primary heterozygous familial hypercholesterolaemia, primary non-familial hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older) Evolocumab : Primary hypercholesterolaemia (heterozygous familial and non-familial), mixed dyslipidaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Fluvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older) Pemafibrate : Dyslipidemia characterised by high TG ≥150 mg/dL – only adults (18 years old or older) Pitavastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older) Pravastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older) Rosuvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only elderly (65 years old or older) Rosuvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 - 65 years old) Simvastatin : Primary hypercholesterolemia, mixed dyslipidaemia – only adults (18 years old or older)
Dyssomnia	Diphenhydramine : Sleep disturbance – only adults (18 years old or older) Valerian : Sleep disturbances – only adults (18 years old or older)
Dystrophic epidermolysis bullosa	Beremagene geperpavec : Dystrophic epidermolysis bullosa – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

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