Indications A-Z

RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.

This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Indications starting with 'R'

Indication	Treatments
Radiation-induced nausea and vomiting	Granisetron : Nausea and vomiting associated with chemotherapy and radiotherapy – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Granisetron : Nausea and vomiting associated with chemotherapy and radiotherapy – only adults (18 years old or older) Granisetron : Prevention of nausea and vomiting associated with chemotherapy and radiotherapy – only adults (18 years old or older) Ondansetron : Radiotherapy induced nausea and vomiting (RINV) – only minors (0 - 18 years old) Ondansetron : Radiotherapy induced nausea and vomiting (RINV) – only adults (18 years old or older)
Radioactive isotope accident	Potassium iodide : Prevention of uptake of radioactive iodine in the thyroid after nuclear accidents – only minors (0 - 18 years old) , adults (18 years old or older)
Radiographic imaging procedure	Metoclopramide : Radiographic imaging procedure – only adults (18 years old or older)
Radionuclide imaging of myocardium using technetium (99m-Tc) sestamibi with cardiac stress test	Regadenoson : Radionuclide imaging of myocardium using technetium (99m-Tc) sestamibi with cardiac stress test – only adults (18 - 65 years old)
Raised calcium phosphate product	Lanthanum : Hyperphosphataemia in chronic renal failure patients – only adults (18 years old or older)
Raised intracranial pressure	Mannitol : Raised intracranial pressure, cerebral oedema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Raised intraocular pressure	Aceclidine : Increased intraocular pressure, glaucoma – only adults (18 years old or older) Brinzolamide : Elevated intraocular pressure, ocular hypertension, open-angle glaucoma – only adults (18 years old or older) Mannitol : Elevated intraocular pressure – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Netarsudil : Elevated intraocular pressure, open-angle glaucoma, ocular hypertension – only adults (18 years old or older) Timolol : Elevated intra-ocular pressure, chronic open-angle glaucoma – only adolescents (12 years - 18 years old) , adults (18 years old or older) Travoprost : Elevated intraocular pressure, ocular hypertension, open-angle glaucoma – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Rapid sequence induction	Rocuronium : Facilitation of tracheal intubation during rapid sequence induction, adjunct in the intensive care unit (ICU) – only adults (18 - 65 years old)
Rat bite fever	Benzylpenicillin : Rat bite fever – only newborns (0 - 40 days old) Benzylpenicillin : Rat bite fever – only infants (40 days - 1 year old) , children (1 year - 12 years old) Benzylpenicillin : Rat bite fever – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Raynaud's disease	Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Raynaud's phenomenon	Iloprost : Severe Raynaud's Phenomenon – only adults (18 - 65 years old)
Re-entrant atrial tachycardia	Propafenone : Ventricular arrhythmias, paroxysmal supraventricular tachyarrhythmias – only adults (18 years old or older)
Re-entrant atrioventricular node tachycardia	Flecainide : Supraventricular arrhythmia, re-entrant atrioventricular node tachycardia, Wolff-Parkinson-White pattern – only elderly (65 years old or older) Flecainide : Supraventricular arrhythmia, re-entrant atrioventricular node tachycardia, Wolff-Parkinson-White pattern – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Reactivation of hepatitis B viral hepatitis	Human hepatitis B immunoglobulin : Hepatitis B virus re-infection after liver transplantation for hepatitis B induced liver failure – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Reactive depression (situational)	Levosulpiride : Endogenous and reactive depression – only adults (18 years old or older)
Reactive hypoglycemia	Glucagon : Severe hypoglycaemic reactions – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Reactive oxygen species 1 positive non-small cell lung cancer	Crizotinib : ROS1-positive advanced non-small cell lung cancer (NSCLC) – only adults (18 years old or older) Entrectinib : ROS1-positive, advanced non-small cell lung cancer – only adults (18 years old or older) Repotrectinib : ROS1-positive non-small cell lung cancer – only adults (18 years old or older)
Recurrent allergic croup	Prednisolone : Spasmodic croup – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Recurrent Clostridium difficile infection	Bezlotoxumab : Prevention of recurrence of Clostridioides difficile infection (CDI) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Recurrent major depressive episodes	Sertraline : Major depressive episodes – only adults (18 years old or older) Venlafaxine : Recurrence of major depressive episodes – only adults (18 years old or older)
Reflux esophagitis	Esomeprazole : Erosive reflux esophagitis – only children (1 year - 12 years old) Esomeprazole : Erosive reflux esophagitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Famotidine : Gastroesophageal reflux disease with esophagitis – only adults (18 years old or older) Lansoprazole : Reflux oesophagitis – only adults (18 years old or older) Omeprazole : Reflux oesophagitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Omeprazole : Reflux oesophagitis – only adults (18 years old or older) Pantoprazole : Reflux oesophagitis – only adults (18 years old or older) Ranitidine : Gastroesophageal reflux disease with esophagitis – only adults (18 years old or older) Sucralfate : Duodenal ulcer, chronic gastritis, peptic esophagitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Refraction assessment	Atropine : Refraction – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Atropine : Refraction – only adults (18 years old or older)
Refractory angina	Glyceryl trinitrate : Refractory unstable angina pectoris – only adults (18 years old or older)
Refractory cytopenia with multilineage dysplasia	Thiotepa : Refractory cytopenia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Refractory cytopenia with multilineage dysplasia and ringed sideroblasts	Luspatercept : Anaemia due to myelodysplastic syndromes (MDS) – only adults (18 years old or older)
Reinfection tuberculosis	Ethambutol : Reinfection tuberculosis – only adults (18 years old or older)
Relapsing remitting multiple sclerosis	Alemtuzumab : Relapsing remitting multiple sclerosis (RRMS) – only adults (18 years old or older) Cladribine : Relapsing multiple sclerosis (MS) – only adults (18 years old or older) Diroximel fumarate : Relapsing remitting multiple sclerosis – only adults (18 years old or older) Fingolimod : Relapsing remitting multiple sclerosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old) Glatiramer : Relapsing forms of multiple sclerosis (MS) – only adults (18 - 65 years old) Interferon beta-1a : Relapsing multiple sclerosis (MS) – only adults (18 years old or older) Methylprednisolone : Acute exacerbations of multiple sclerosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Methylprednisolone : Acute exacerbations of multiple sclerosis – only adults (18 years old or older) Natalizumab : Relapsing remitting multiple sclerosis – only adults (18 - 65 years old) Ozanimod : Relapsing remitting multiple sclerosis (RRMS) – only adults (18 years old or older) Peginterferon beta-1a : Relapsing remitting multiple sclerosis – only adults (18 - 65 years old) Ponesimod : Relapsing forms of multiple sclerosis (RMS) – only adults (18 years old or older) Teriflunomide : Relapsing remitting multiple sclerosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Ublituximab : Relapsing forms of multiple sclerosis – only adults (18 years old or older)
Renal cell carcinoma	Avelumab : Advanced renal cell carcinoma – only adults (18 years old or older) Bevacizumab : Advanced and/or metastatic renal cell cancer – only adults (18 years old or older) Cabozantinib : Renal cell carcinoma (RCC) - combination treatment with nivolumab – only adults (18 years old or older) Cabozantinib : Renal cell carcinoma (RCC) - monotherapy – only adults (18 years old or older) Everolimus : Advanced renal cell carcinoma – only adults (18 years old or older) Ipilimumab : Renal cell carcinoma – only adults (18 years old or older) Nivolumab : Renal cell carcinoma (RCC) – only adults (18 years old or older) Nivolumab : Renal cell carcinoma (RCC) - combination treatment with cabozantinib – only adults (18 years old or older) Nivolumab : Renal cell carcinoma (RCC) - combination treatment with ipilimumab – only adults (18 years old or older) Pazopanib : Renal cell carcinoma (RCC) – only adults (18 years old or older) Pembrolizumab : First-line treatment of advanced renal cell carcinoma in combination with axitinib – only adults (18 years old or older) Pembrolizumab : First-line treatment of advanced renal cell carcinoma in combination with lenvatinib – only adults (18 years old or older) Pembrolizumab : Renal cell carcinoma in patients at increased risk of recurrence following nephrectomy – only adults (18 years old or older) Sorafenib : Renal cell carcinoma – only adults (18 years old or older) Sunitinib : Metastatic renal cell carcinoma (MRCC) – only adults (18 years old or older) Temsirolimus : Renal cell carcinoma – only adults (18 years old or older) Tivozanib : Renal cell carcinoma (RCC) – only adults (18 years old or older)
Renal dialysis	Epoprostenol : Renal Dialysis – only adults (18 years old or older) Sucroferric oxyhydroxide : Chronic kidney disease on dialysis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Renal function impairment with growth failure	Somatropin : Growth disturbance associated with chronic renal insufficiency – only minors (0 - 18 years old)
Renal osteodystrophy	Calcitriol : Renal osteodystrophy – only adults (18 years old or older)
Renal transplant rejection	Tacrolimus : Prophylaxis of transplant rejection in renal allograft recipients – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Tacrolimus : Prophylaxis of transplant rejection in renal allograft recipients – only adults (18 years old or older)
Respiratory syncytial virus bronchiolitis	Nirsevimab : Respiratory Syncytial Virus (RSV) lower respiratory tract disease – only newborns (0 - 40 days old) , infants (40 days - 1 year old) RSV glycoprotein F antigen : Lower respiratory tract disease (LRTD) caused by respiratory syncytial virus – only adults (18 years old or older)
Respiratory syncytial virus bronchitis	Nirsevimab : Respiratory Syncytial Virus (RSV) lower respiratory tract disease – only newborns (0 - 40 days old) , infants (40 days - 1 year old) RSV glycoprotein F antigen : Lower respiratory tract disease (LRTD) caused by respiratory syncytial virus – only adults (18 years old or older)
Respiratory syncytial virus laryngotracheobronchitis	Nirsevimab : Respiratory Syncytial Virus (RSV) lower respiratory tract disease – only newborns (0 - 40 days old) , infants (40 days - 1 year old) RSV glycoprotein F antigen : Lower respiratory tract disease (LRTD) caused by respiratory syncytial virus – only adults (18 years old or older)
Respiratory tract infection	Sultamicillin : Infections caused by susceptible microorganisms – only children (1 year - 12 years old) Sultamicillin : Infections caused by susceptible microorganisms – only adults (18 years old or older)
Restless legs	Pramipexole : Moderate to severe idiopathic Restless Legs Syndrome – only adults (18 years old or older) Rotigotine : Restless Legs Syndrome (RLS) – only adults (18 years old or older)
Retinal vasculitis	Prednisolone : Retinal vasculitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Retinoblastoma	22-Oxovincaleukoblastine : Retinoblastoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Retinopathy of prematurity	Ranibizumab : Retinopathy of prematurity (ROP) – only newborns (0 - 40 days old) , infants (40 days - 1 year old)
Rett's disorder	Trofinetide : Rett syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Reversal of neuromuscular blockade	Neostigmine : Antagonist to non-depolarizing neuromuscular blockade – only minors (0 - 18 years old) , adults (18 years old or older) Sugammadex : Reversal of neuromuscular blockade induced by rocuronium or vecuronium – only adults (18 years old or older) Sugammadex : Routine reversal of rocuronium induced blockade – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Reversal of opiate activity	Naloxone : Complete or partial reversal of central nervous system caused by opioids – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Naloxone : Reversal of respiratory and other CNS depression in the neonate whose mothers have received opioids – only newborns (0 - 40 days old)
Reversal of sedation	Flumazenil : Reversal of sedation – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Flumazenil : Reversal of sedation – only adults (18 years old or older)
Rheumatic fever	Acetylsalicylic acid : Rheumatic fever – only adolescents (12 years - 18 years old) Acetylsalicylic acid : Rheumatic fever, rheumatoid arthritis, osteoarthritis (adults) – only adults (18 years old or older)
Rheumatoid arthritis	Abatacept : Active rheumatoid arthritis – only adults (18 years old or older) Acemetacin : Osteoarthritis, rheumatoid arthritis, pain, inflammation – only adults (18 - 65 years old) Acetylsalicylic acid : Rheumatic fever, rheumatoid arthritis, osteoarthritis (adults) – only adults (18 years old or older) Adalimumab : Rheumatoid arthritis – only adults (18 years old or older) Anakinra : Rheumatoid arthritis (RA) – only adults (18 years old or older) Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older) Baricitinib : Rheumatoid arthritis – only adults (18 years old or older) Celecoxib : Rheumatoid arthritis – only adults (18 years old or older) Certolizumab pegol : Rheumatoid arthritis – only adults (18 years old or older) Chloroquine : Rheumatoid arthritis – only adults (18 years old or older) Ciclosporin : Rheumatoid arthritis – only adults (18 years old or older) Dexamethasone : Rheumatoid arthritis – only adults (18 years old or older) Etanercept : Rheumatoid arthritis – only adults (18 years old or older) Etofenamate : Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, folliculitis, periarthritis Etoricoxib : Rheumatoid arthritis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Filgotinib : Rheumatoid arthritis – only elderly (65 years old or older) Filgotinib : Rheumatoid arthritis – only adults (18 - 65 years old) Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Golimumab : Rheumatoid arthritis – only adults (18 years old or older) Hydroxychloroquine : Rheumatoid arthritis, discoid and systemic lupus erythematosus, sunlight damaged skin – only adults (18 years old or older) Ibuprofen : Rheumatoid arthritis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Indometacin : Rheumatoid arthritis – only adults (18 years old or older) Infliximab : Rheumatoid arthritis – only adults (18 years old or older) Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older) Leflunomide : Rheumatoid arthritis – only adults (18 years old or older) Lornoxicam : Rheumatoid arthritis – only adults (18 years old or older) Mefenamic acid : Rheumatoid arthritis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Meloxicam : Rheumatoid arthritis – only elderly (65 years old or older) Meloxicam : Rheumatoid arthritis – only adults (18 - 65 years old) Methotrexate : Rheumatoid arthritis – only adults (18 years old or older) Methylprednisolone : Rheumatoid arthritis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Nabumetone : Osteoarthritis, rheumatoid arthritis – only adults (18 years old or older) Naproxen : Rheumatic arthritis, osteoarthritis, ankylosing spondylitis – only adults (18 years old or older) Oxaprozin : Rheumatoid arthritis, ankylosing spondylitis – only adults (18 years old or older) Piroxicam : Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis – only adults (18 years old or older) Prednisolone : Rheumatoid arthritis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Prednisolone : Rheumatoid arthritis – only adults (18 years old or older) Rituximab : Rheumatoid arthritis – only adults (18 years old or older) Sarilumab : Moderately to severely active rheumatoid arthritis – only adults (18 years old or older) Tofacitinib : Rheumatoid arthritis – only adults (18 years old or older) Triamcinolone : Rheumatoid arthritis, juvenile idiopathic arthritis, osteoarthritis, post-traumatic arthritis, synovitis, tendinitis, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Upadacitinib : Rheumatoid arthritis – only adults (18 years old or older)
Rhinitis	Ketotifen : Allergic conditions – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Rhytide of forehead	Botulinum toxin type A : Forehead lines seen at maximum eyebrow elevation – only adults (18 - 65 years old)
Rhytide of glabellar skin	Botulinum toxin type A : Glabellar lines seen at maximum frown – only adults (18 years old or older)
RMSF - Rocky Mountain spotted fever	Doxycycline : Rocky Mountain spotted fever – only adults (18 years old or older)
Rosacea	Ivermectin : Rosacea – only adults (18 - 65 years old) Tetracycline : Severe rosacea – only adolescents (12 years - 18 years old) , adults (18 years old or older)

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