Indications A-Z

RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.

This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Indications starting with 'P'

Indication	Treatments
Pain	Acetylsalicylic acid : Fever, pain – only adults (18 years old or older) Acetylsalicylic acid : Pain – only adolescents (12 years - 18 years old) Codeine : Mild to moderate pain – only adolescents (12 years - 18 years old) , adults (18 years old or older) Dexketoprofen : Pain – only adults (18 years old or older) Dihydrocodeine : Severe pain in cancer and other chronic conditions – only adolescents (12 years - 18 years old) , adults (18 years old or older) Fentanyl : Breakthrough pain (BTP) – only adults (18 years old or older) Levomepromazine : Severe pain – only adults (18 years old or older) Levomepromazine : Severe pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Lornoxicam : Pain – only adults (18 years old or older) Mefenamic acid : Pain – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Nitrous oxide (N2O) : Pain – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Paracetamol : Pain, fever – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pain at rest due to peripheral vascular disease	Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Pain of ear	Paracetamol : Pain, fever – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pain provoked by rest	Pentoxifylline : Peripheral vascular disease, intermittent claudication, rest pain – only adults (18 years old or older)
Painful swelling of joint	Ibuprofen : Painful swelling of joint – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pancreatic adenocarcinoma	Gemcitabine : Adenocarcinoma of the pancreas – only adults (18 years old or older) Paclitaxel : Adenocarcinoma of pancreas – only adults (18 years old or older)
Pancreatic fistula	Lanreotide : Postoperative pancreatic fistula, postoperative small bowel fistula – only adults (18 years old or older)
Pancreatic insufficiency	Cimetidine : Pancreatic insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Cimetidine : Pancreatic insufficiency – only infants (40 days - 1 year old) Cimetidine : Pancreatic insufficiency – only adults (18 years old or older)
Panic disorder	Alprazolam : Panic disorder with or without agoraphobia – only adults (18 years old or older) Citalopram : Panic disorder with or without agoraphobia – only elderly (65 years old or older) Citalopram : Panic disorder with or without agoraphobia – only adults (18 - 65 years old) Escitalopram : Panic disorder with or without agoraphobia – only adults (18 years old or older) Paroxetine : Panic disorder with and without agoraphobia – only adults (18 years old or older) Sertraline : Panic disorder with or without agoraphobia – only adults (18 years old or older) Venlafaxine : Panic disorder – only adults (18 years old or older)
Panuveitis in Behcet's syndrome	Ciclosporin : Behçet uveitis – only adults (18 years old or older)
Paralytic ileus	Neostigmine : Paralytic ileus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Pyridostigmine : Paralytic ileus, post-operative urinary retention – only adults (18 years old or older)
Paraphilia	Cyproterone : Severe hypersexuality, sexual deviation – men, only adults (18 - 65 years old)
Paratyphoid fever	Amoxicillin : Typhoid and paratyphoid fever – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Parkinson's disease	Amantadine : Parkinson’s disease – only adults (18 years old or older) Bromocriptine : Parkinson's Disease – only adults (18 years old or older) Entacapone : Parkinson's disease – only adults (18 years old or older) Levodopa : Parkinson's disease – only adults (18 years old or older) Opicapone : Parkinson's disease – only adults (18 years old or older) Piribedil : Parkinson's disease – only adults (18 years old or older) Piribedil : Parkinson's disease – only adults (18 years old or older) Pramipexole : Parkinson's disease – only adults (18 years old or older) Rasagiline : Parkinson's disease – only adults (18 years old or older) Ropinirole : Parkinson's disease – only adults (18 years old or older) Ropinirole : Parkinson's disease – only adults (18 years old or older) Rotigotine : Parkinson's disease – only adults (18 years old or older) Rotigotine : Parkinson's disease – only adults (18 years old or older) Safinamide : Parkinson's disease – only adults (18 years old or older) Selegiline : Parkinson's disease – only adults (18 years old or older) Selegiline : Parkinson's disease – only adults (18 years old or older) Tolcapone : Idiopathic Parkinson's disease – only adults (18 - 65 years old)
Parkinsonism	Biperiden : Parkinsonism – only adults (18 years old or older) Diphenhydramine : Parkinsonism – only adults (18 years old or older) Orphenadrine : Parkinsonism – only adults (18 years old or older)
Paroxysmal atrial flutter	Propafenone : Ventricular arrhythmias, paroxysmal supraventricular tachyarrhythmias – only adults (18 years old or older)
Paroxysmal nocturnal dyspnea	Aminophylline : Pulmonary oedema, paroxysmal nocturnal dyspnoea, status asthmaticus, acute bronchospasm – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Paroxysmal nocturnal hemoglobinuria	Eculizumab : Paroxysmal nocturnal haemoglobinuria (PNH) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Eculizumab : Paroxysmal nocturnal haemoglobinuria (PNH) – only adults (18 years old or older) Ravulizumab : Paroxysmal nocturnal haemoglobinuria (PNH) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Paroxysmal supraventricular tachycardia	Adenine Deoxy Nucleoside : Paroxysmal supraventricular tachycardias, Wolff-Parkinson-White Syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Adenine Deoxy Nucleoside : Paroxysmal supraventricular tachycardias, Wolff-Parkinson-White Syndrome – only adults (18 years old or older) Antazoline : Paroxysmal arrhythmias of supraventricular origin – only adults (18 years old or older) Neostigmine : Paroxysmal supraventricular tachycardia – only adults (18 - 65 years old) Verapamil : Paroxysmal supraventricular tachycardia – only adults (18 years old or older) Verapamil : Paroxysmal supraventricular tachycardia – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) Verapamil : Paroxysmal supraventricular tachycardia – only newborns (0 - 40 days old)
Passing flatus	Magnesium hydroxide : Stomach discomfort, indigestion, hyperacidity, heartburn, flatulence – only children (1 year - 12 years old) Magnesium hydroxide : Stomach discomfort, indigestion, hyperacidity, heartburn, flatulence – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pasteurella infection	Benzylpenicillin : Pasteurellosis – only newborns (0 - 40 days old) Benzylpenicillin : Pasteurellosis – only infants (40 days - 1 year old) , children (1 year - 12 years old) Benzylpenicillin : Pasteurellosis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Patent ductus arteriosus	Alprostadil : Temporary maintenance of patency of the ductus arteriosus until corrective or palliative surgery – only newborns (0 - 40 days old)
Pathological fracture	Zoledronic acid : Prevention of skeletal related events – only adults (18 years old or older)
Paucibacillary leprosy	Dapsone : Paucibacillary leprosy – only children (1 year - 12 years old) Dapsone : Paucibacillary leprosy – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pemphigus vulgaris	Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Pemphigus vulgaris – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prednisolone : Pemphigus vulgaris – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Peptic ulcer	Magaldrate : Ulcer of the upper digestive tract – only adults (18 years old or older) Pantoprazole : Peptic ulcer – only adults (18 years old or older)
Percutaneous coronary intervention	Bivalirudin : Percutaneous coronary intervention – only adults (18 years old or older)
Percutaneous transluminal coronary angioplasty	Abciximab : Percutaneous coronary intervention – only adults (18 years old or older) Isosorbide dinitrate : Percutaneous transluminal coronary angioplasty – only adults (18 years old or older)
Perennial allergic conjunctivitis	Azelastine : Non-seasonal (perennial) allergic conjunctivitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Cromoglicic acid : Seasonal and perennial allergic conjunctivitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Mizolastine : Seasonal allergic rhinoconjunctivitis (hay fever), perennial allergic rhinoconjunctivitis, urticaria – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Perennial allergic rhinitis with seasonal variation	Cetirizine : Seasonal and perennial allergic rhinitis, chronic idiopathic urticaria – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Perianal fistula due to Crohn's disease	Darvadstrocel : Complex perianal fistulas in nonactive/mildly active luminal Crohn’s disease – only adults (18 years old or older)
Periarthritis	Etofenamate : Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, folliculitis, periarthritis Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Piroxicam : Osteoarthritis of superficial joints, acute musculoskeletal injuries, periarthritis, epicondylitis, tendinitis, tenosynovitis – only adults (18 years old or older)
Peribulbar infiltration of local anesthetic	Chloroprocaine : Peribulbar block – only adults (18 - 65 years old) Levobupivacaine : Ophthalmic anaesthesia (peribulbar block) – only adults (18 years old or older)
Pericoronitis	Serrapeptase : Pericoronitis – only adults (18 years old or older)
Perineal wart	Imiquimod : External genital and perianal warts (condylomata acuminata) – only adults (18 years old or older)
Period pain	Dexketoprofen : Pain – only adults (18 years old or older) Flurbiprofen : Dysmenorrhoea – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Ibuprofen : Dysmenorrhoea – women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Indometacin : Dysmenorrhea – women, only adults (18 - 65 years old) Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older) Naproxen : Dysmenorrhoea – women, only adults (18 years old or older) Norethisterone : Dysfunctional uterine bleeding, polymenorrhoea, menorrhagia, dysmenorrhoea, metropathia haemorrhagia – women, only adults (18 - 65 years old) Paracetamol : Dysmenorrhea – women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Periodic disease	Canacinumab : Familial Mediterranean fever (FMF) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Peripheral arterial occlusive disease	Clopidogrel : Peripheral arterial disease – only adults (18 years old or older) Heparin : Acute peripheral arterial occlusion – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Heparin : Acute peripheral arterial occlusion – only adults (18 years old or older)
Peripheral block anesthesia	Bupivacaine : Major nerve block – only children (1 year - 12 years old) Bupivacaine : Major nerve block – only adolescents (12 years - 18 years old) , adults (18 years old or older) Levobupivacaine : Peripheral nerve anaesthesia – only adults (18 years old or older) Lidocaine : Peripheral block anesthesia – only adults (18 years old or older)
Peripheral blood stem cell graft	Lenograstim : Mobilisation of peripheral blood progenitor cells (PBPCs) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Peripheral circulatory disorder associated with type 2 diabetes mellitus	Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Peripheral edema	Furosemide : Oedema – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) Furosemide : Oedema – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Peripheral gangrene	Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Peripheral neuropathic pain	Capsaicin : Peripheral neuropathic pain – only adults (18 years old or older) Gabapentin : Peripheral neuropathic pain – only adults (18 years old or older)
Peripheral vascular disease	Pentoxifylline : Peripheral vascular disease, intermittent claudication, rest pain – only adults (18 years old or older)
Peripheral venous insufficiency	Diosmin : Venolymphatic insufficiency – only adults (18 years old or older) Troxerutin : Oedema associated with chronic venous insufficiency – only adults (18 years old or older)
Persistent pulmonary hypertension of the newborn	Nitric oxide (NO) : Persistent pulmonary hypertension of the newborn (PPHN) – only newborns (0 - 40 days old)
Persistent trophoblastic disease	Etoposide : Gestational trophoblastic neoplasia – only adults (18 - 65 years old)
Ph positive ALL	Imatinib : Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Imatinib : Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) – only adults (18 years old or older) Ponatinib : Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) – only adults (18 years old or older)
Pharyngeal candidiasis	Fluconazole : Oropharyngeal candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Miconazole : Candidosis of the oropharynx – only newborns (0 - 40 days old) , infants (40 days - 1 year old) Miconazole : Candidosis of the oropharynx – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Posaconazole : Oropharyngeal candidiasis – only adults (18 years old or older)
Philadelphia chromosome positive chronic myelogenous leukaemia	Asciminib : Philadelphia chromosome-positive chronic myeloid leukaemia in chronic phase (Ph+ CML-CP) – only adults (18 years old or older) Bosutinib : Philadelphia chromosome-positive chronic myelogenous leukaemia (Ph+ CML) – only adults (18 years old or older) Dasatinib : Chronic myelogenous leukaemia (CML) Philadelphia chromosome positive (Ph+) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Dasatinib : Chronic myelogenous leukaemia (CML) Philadelphia chromosome positive (Ph+) – only adults (18 years old or older) Imatinib : Chronic myeloid leukaemia (CML) Philadelphia chromosome (bcr-abl) positive (Ph+) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Imatinib : Chronic myeloid leukaemia (CML) Philadelphia chromosome (bcr-abl) positive (Ph+) – only adults (18 years old or older) Nilotinib : Philadelphia chromosome positive chronic myelogenous leukaemia (CML) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Nilotinib : Philadelphia chromosome positive chronic myelogenous leukaemia (CML) – only adults (18 years old or older)
Photodermatitis	Clobetasone : Atopic dermatitis, irritant or allergic contact dermatitis, seborrhoeic dermatitis, nappy rash, photodermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Physical aggression	Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only elderly (65 years old or older) Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only adults (18 - 65 years old)
Pituitary dependent hypercortisolism	Pasireotide : Cushing's disease – only adults (18 years old or older)
Pityriasis capitis	Ketoconazole : Dandruff – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pityriasis versicolor	Clotrimazole : Pityriasis versicolor Econazole : Pityriasis versicolor – only adolescents (12 years - 18 years old) , adults (18 years old or older) Ketoconazole : Tinea versicolor – only adolescents (12 years - 18 years old) , adults (18 years old or older) Terbinafine : Pityriasis versicolor – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Plaque psoriasis	Adalimumab : Moderate to severe chronic plaque psoriasis – only adults (18 years old or older) Adalimumab : Paediatric plaque psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Bimekizumab : Moderate to severe plaque psoriasis – only adults (18 years old or older) Brodalumab : Moderate to severe plaque psoriasis – only adults (18 years old or older) Calcitriol : Plaque psoriasis – only adults (18 - 65 years old) Certolizumab pegol : Plaque psoriasis – only adults (18 years old or older) Deucravacitinib : Moderate to severe plaque psoriasis – only adults (18 years old or older) Dimethyl fumarate : Moderate to severe plaque psoriasis – only adults (18 years old or older) Efalizumab : Chronic plaque psoriasis – only adults (18 years old or older) Etanercept : Plaque psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Guselkumab : Moderate to severe plaque psoriasis – only adults (18 years old or older) Ixekizumab : Plaque psoriasis – only adults (18 years old or older) Risankizumab : Moderate to severe plaque psoriasis – only adults (18 years old or older) Secukinumab : Plaque psoriasis – only adults (18 years old or older) Tazarotene : Mild to moderate plaque psoriasis – only adults (18 - 65 years old) Tildrakizumab : Plaque psoriasis – only adults (18 years old or older) Ustekinumab : Paediatric plaque psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Ustekinumab : Plaque psoriasis – only adults (18 years old or older)
Pleural effusion due to malignant neoplastic disease	Bleomycin : Malignant pleural effusion – only adults (18 years old or older)
Pneumocystosis pneumonia	Atovaquone : Mild to moderate pneumocystis pneumonia caused by Pneumocystis jiroveci – only adults (18 - 65 years old)
Pneumonia caused by respiratory syncytial virus	Nirsevimab : Respiratory Syncytial Virus (RSV) lower respiratory tract disease – only newborns (0 - 40 days old) , infants (40 days - 1 year old) RSV glycoprotein F antigen : Lower respiratory tract disease (LRTD) caused by respiratory syncytial virus – only adults (18 years old or older)
Poisoning by drug AND/OR medicinal substance	Mannitol : Elimination of renally excreted toxic substances in poisoning – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Poisoning by iron	Deferoxamine : Acute iron poisoning – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Poisoning by paracetamol	Acetylcysteine : Treatment of paracetamol overdose
Poisoning by pyrimethamine	Calcium folinate : Antidote for pyrimethamine toxicity – only adults (18 years old or older)
Poisoning due to chemical substance	Charcoal activated : Acute oral poisoning, drug overdose – only adolescents (12 years - 18 years old) , adults (18 years old or older) Charcoal activated : Acute oral poisoning, drug overdose – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Pollinosis	Chlorphenamine : Hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy – only children (1 year - 12 years old) , elderly (65 years old or older) Chlorphenamine : Hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Mequitazine : Hay fever, perennial rhinitis, urticaria, allergic pruritis, insect bites, stings – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Polyarteritis nodosa	Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older) Dexamethasone : Polyarteritis nodosa – only adults (18 years old or older) Prednisolone : Polyarteritis nodosa – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Polycystic ovary syndrome	Bromocriptine : Polycystic ovary syndrome – women, only adults (18 - 65 years old)
Polygenic hypercholesterolaemia	Alirocumab : Primary heterozygous familial hypercholesterolaemia, primary non-familial hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older) Evolocumab : Primary hypercholesterolaemia (heterozygous familial and non-familial), mixed dyslipidaemia – only adults (18 years old or older)
Polymenorrhea	Norethisterone : Dysfunctional uterine bleeding, polymenorrhoea, menorrhagia, dysmenorrhoea, metropathia haemorrhagia – women, only adults (18 - 65 years old)
Polymyalgia rheumatica	Dexamethasone : Polymyalgia rheumatica – only adults (18 years old or older) Methylprednisolone : Polymyalgia rheumatica – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prednisolone : Polymyalgia rheumatica – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Polymyositis	Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Polymyositis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prednisolone : Polymyositis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Polyp of nasal cavity	Mometasone : Nasal polyposis – only adults (18 years old or older)
Polyp of nasal cavity and/or nasal sinus	Budesonide : Nasal polyps – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Polyuria	Desmopressin : Nocturia – only adults (18 - 65 years old)
Porphobilinogen synthase deficiency	Givosiran : Acute hepatic porphyria (AHP) – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Portal hypertension	Propranolol : Portal hypertension – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Post-essential thrombocythaemia myelofibrosis	Fedratinib : Primary myelofibrosis, post polycythaemia vera myelofibrosis, post essential thrombocythaemia myelofibrosis – only adults (18 years old or older)
Post-polycythaemia vera myelofibrosis	Fedratinib : Primary myelofibrosis, post polycythaemia vera myelofibrosis, post essential thrombocythaemia myelofibrosis – only adults (18 years old or older)
Post-transplant lymphoproliferative disorder	Tabelecleucel : Epstein-Barr virus positive post-transplant lymphoproliferative disease (EBV+ PTLD) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Posterior uveitis	Methylprednisolone : Posterior uveitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prednisolone : Posterior uveitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Postherpetic neuralgia	Attenuated varicella-zoster virus : Herpes zoster, post-herpetic neuralgia (PHN) – only adults (18 years old or older)
Postmenopausal hormone replacement therapy	Progesterone : Hormone replacement therapy (HRT) – women, only adults (18 - 65 years old)
Postmenopausal osteoporosis	Abaloparatide : Osteoporosis – women, only adults (18 years old or older) Bazedoxifene : Postmenopausal osteoporosis – women, only adults (18 years old or older) Calcitonin : Established postmenopausal osteoporosis – women, only adults (18 years old or older) Calcitonin : Established postmenopausal osteoporosis – women, only adults (18 years old or older) Calcitriol : Post-menopausal osteoporosis – only adults (18 years old or older) Raloxifene : Post-menopausal osteoporosis – women, only adults (18 years old or older) Raloxifene : Post-menopausal osteoporosis – women, only adults (18 years old or older) Risedronic acid : Postmenopausal osteoporosis – women, only adults (18 years old or older)
Postmyocardial infarction syndrome	Prednisolone : Postmyocardial infarction syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Postoperative intestinal obstruction	Trimebutine : Postoperative paralytic ileus – only adults (18 years old or older)
Postoperative nausea	Granisetron : Post-operative nausea and vomiting (PONV) – only adults (18 years old or older)
Postoperative nausea and vomiting	Granisetron : Post-operative nausea and vomiting (PONV) – only adults (18 years old or older) Haloperidol : Postoperative nausea and vomiting – only adults (18 years old or older) Ondansetron : Post operative nausea and vomiting (PONV) – only minors (0 - 18 years old) Ondansetron : Post operative nausea and vomiting (PONV) – only adults (18 years old or older) Tropisetron : Post-operative nausea and vomiting – only adults (18 - 65 years old)
Postoperative pain	Acemetacin : Osteoarthritis, rheumatoid arthritis, pain, inflammation – only adults (18 - 65 years old) Dihydrocodeine : Post-operative pain – only adolescents (12 years - 18 years old) , adults (18 years old or older) Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Levobupivacaine : Postoperative pain – only adults (18 years old or older) Nalbuphine : Moderate to severe pain, postoperative pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Nalbuphine : Moderate to severe pain, postoperative pain – only adults (18 years old or older) Parecoxib : Postoperative pain – only adults (18 years old or older) Sufentanil : Postoperative pain – only adults (18 years old or older)
Postoperative retention of urine	Neostigmine : Post-operative urinary retention – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Pyridostigmine : Paralytic ileus, post-operative urinary retention – only adults (18 years old or older)
Postoperative uveitis	Loteprednol : Post-operative inflammation following ocular surgery – only adults (18 years old or older) Rimexolone : Postoperative inflammation following ocular surgery – only adults (18 years old or older)
Postoperative vomiting	Granisetron : Post-operative nausea and vomiting (PONV) – only adults (18 years old or older)
Postpartum hemorrhage	Carboprost : Post-partum haemorrhage – women, only adults (18 - 65 years old) Ergometrine : Post-partum haemorrhage – women, only adults (18 - 65 years old)
Postpartum hemorrhage co-occurrent and due to uterine rupture following obstructed labor	Oxytocin : Postpartum uterine haemorrhage – women, only adults (18 - 65 years old) Oxytocin : Postpartum uterine haemorrhage – women, only adults (18 - 65 years old)
Posttransplant hyperlipidemia	Pravastatin : Post transplantation hyperlipidaemia – only adults (18 years old or older)
Posttraumatic stress disorder	Paroxetine : Posttraumatic stress disorder – only adults (18 years old or older) Sertraline : Post traumatic stress disorder (PTSD) – only adults (18 years old or older)
Prader-Willi syndrome	Somatropin : Prader-Willi syndrome (PWS) – only minors (0 - 18 years old)
Precursor T-cell lymphoblastic lymphoma	Nelarabine : T-cell lymphoblastic lymphoma (T-LBL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Nelarabine : T-cell lymphoblastic lymphoma (T-LBL) – only adults (18 years old or older)
Preinfarction syndrome	Abciximab : Unstable angina – only adults (18 years old or older) Acetylsalicylic acid : Stable and unstable angina pectoris – only adults (18 years old or older) Bivalirudin : Treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction – only adults (18 years old or older) Dalteparin : Unstable angina, non-Q wave myocardial infarction – only adults (18 years old or older) Eptifibatide : Unstable angina, non-Q-wave myocardial infarction – only adults (18 years old or older) Heparin : Unstable angina pectoris – only adults (18 years old or older) Nadroparin : Unstable angina, non-Q wave myocardial infarction – only adults (18 years old or older) Tirofiban : Acute coronary syndromes without ST elevation (NSTE-ACS) – only adults (18 years old or older)
Premature ejaculation	Dapoxetine : Premature ejaculation (PE) – men, only adults (18 - 65 years old)
Premature labor	Atosiban : Pre-term birth – women, only adults (18 - 65 years old)
Premedication for anesthetic procedure	Diazepam : Premedication before surgery or dental procedures – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Diazepam : Premedication before surgery or dental procedures – only elderly (65 years old or older) Diazepam : Premedication before surgery or dental procedures – only adults (18 - 65 years old) Lorazepam : Premedication – only elderly (65 years old or older) Lorazepam : Premedication – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Lorazepam : Premedication – only adults (18 - 65 years old) Midazolam : Premedication – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) Midazolam : Premedication – only adults (18 - 65 years old)
Premenstrual tension syndrome	Norethisterone : Pre-menstrual syndrome – women, only adults (18 - 65 years old)
Preoperative disinfection of skin	Hydrogen peroxide : Disinfection – only adults (18 years old or older) Povidone iodine : Antisepsis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Preparation of bowel for surgery	Neomycin : Pre-operative sterilisation of the bowel – only children (1 year - 12 years old) Neomycin : Pre-operative sterilisation of the bowel – only adolescents (12 years - 18 years old) Neomycin : Pre-operative sterilisation of the bowel – only adults (18 years old or older)
Prevention of deep vein thrombosis	Dalteparin : Prophylaxis of venous thromboembolism in medical patients – only adults (18 years old or older)
Prevention of dental caries	Sodium fluoride : Prevention of dental caries – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Primary adenocarcinoma of esophagogastric junction	Docetaxel : Gastric adenocarcinoma, adenocarcinoma of the gastroesophageal junction – only adults (18 years old or older) Ramucirumab : Advanced gastric cancer, gastro-oesophageal junction adenocarcinoma – only adults (18 years old or older)
Primary adrenocortical insufficiency	Dexamethasone : Primary adrenocortical insufficiency – only adults (18 years old or older) Fludrocortisone : Primary adrenocortical insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Primary adrenocortical insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary biliary cirrhosis	Obeticholic acid : Primary biliary cholangitis – only adults (18 years old or older) Ursodeoxycholic acid : Primary biliary cholangitis – only adults (18 years old or older)
Primary cutaneous diffuse large cell B-cell lymphoma	Tisagenlecleucel : Relapsed or refractory diffuse large B-cell lymphoma (DLBCL) – only adults (18 - 65 years old)
Primary cutaneous T-cell lymphoma	Bexarotene : Cutaneous T-cell lymphoma (CTCL) – only adults (18 years old or older)
Primary differentiated carcinoma of thyroid gland	Lenvatinib : Differentiated (papillary/follicular/Hürthle cell) thyroid carcinoma (DTC) – only adults (18 years old or older) Sorafenib : Differentiated thyroid carcinoma – only adults (18 years old or older)
Primary dysmenorrhea	Dexibuprofen : Primary dysmenorrhoea – women, only adults (18 years old or older) Mefenamic acid : Primary dysmenorrhoea – women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Nimesulide : Primary dysmenorrhea – women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Primary gout	Allopurinol : Gouty arthritis, skin tophi, nephrolithiasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Allopurinol : Gouty arthritis, skin tophi, nephrolithiasis – only adults (18 years old or older) Colchicine : Acute gout – only adults (18 years old or older) Lesinurad : Hyperuricaemia in gout – only adults (18 years old or older) Naproxen : Acute gout – only adults (18 years old or older)
Primary hyperaldosteronism	Spironolactone : Primary aldosteronism – only adults (18 years old or older)
Primary hypercholesterolemia	Atorvastatin : Primary hypercholesterolaemia, combined hyperlipidaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Colesevelam : Primary hypercholesterolaemia – only adults (18 years old or older) Ezetimibe : Primary hypercholesterolaemia – only adults (18 years old or older) Fluvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older) Gemfibrozil : Severe hypertriglyceridaemia, mixed hyperlipidaemia, primary hypercholesterolaemia – only adults (18 years old or older) Inclisiran : Primary hypercholesterolaemia – only adults (18 years old or older) Pitavastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older) Pravastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older) Rosuvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only elderly (65 years old or older) Rosuvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 - 65 years old) Simvastatin : Primary hypercholesterolemia, mixed dyslipidaemia – only adults (18 years old or older)
Primary hyperoxaluria, type I	Lumasiran : Primary hyperoxaluria type 1 (PH1) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary immune deficiency disorder	Human normal immunoglobulin G : Primary immunodeficiency syndromes with impaired antibody production, secondary immunodeficiencies (SID) – only minors (0 - 18 years old) , adults (18 - 65 years old) Immunoglobulins, normal human, IV : Primary immunodeficiency syndromes (PID) with impaired antibody production – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary insomnia	Melatonin : Primary insomnia – only adults (18 years old or older)
Primary irritant dermatitis	Alclometasone : Eczema, primary irritant and allergic dermatitis – only adults (18 years old or older) Betamethasone : Irritant contact dermatitis, allergic contact dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Clobetasone : Atopic dermatitis, irritant or allergic contact dermatitis, seborrhoeic dermatitis, nappy rash, photodermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary malignant neoplasm of adrenal cortex	Mitotane : Adrenal cortical carcinoma (ACC) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Mitotane : Adrenal cortical carcinoma (ACC) – only adults (18 years old or older)
Primary malignant neoplasm of endometrium	Dostarlimab : Endometrial cancer (EC) – only adults (18 years old or older)
Primary malignant neoplasm of rectum	Bevacizumab : Metastatic carcinoma of the colon or rectum (mCRC) – only adults (18 years old or older)
Primary malignant neoplasm of testis	Bleomycin : Testicular carcinoma (seminoma and non-seminoma) – men, only adults (18 years old or older)
Primary malignant neoplasm of the peritoneum	Rucaparib : Epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer – only adults (18 years old or older)
Primary malignant neoplasm of urethra	Vinflunine : Transitional cell carcinoma of the urothelial tract – only elderly (65 years old or older) Vinflunine : Transitional cell carcinoma of the urothelial tract – only adults (18 - 65 years old)
Primary nocturnal enuresis	Desmopressin : Primary nocturnal enuresis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Primary open angle glaucoma	Acetazolamide : Chronic simple glaucoma (open angle) – only adults (18 years old or older) Apraclonidine : Chronic glaucoma – only adults (18 years old or older) Betaxolol : Ocular hypertension, chronic open angle glaucoma – only adults (18 years old or older) Bimatoprost : Chronic open-angle glaucoma, ocular hypertension – only adults (18 years old or older) Carteolol : Ocular hypertension, chronic open angle glaucoma, secondary glaucomas – only adults (18 years old or older) Levobunolol : Chronic open-angle glaucoma, ocular hypertension – only adults (18 years old or older) Pilocarpine : Chronic simple glaucoma – only adults (18 years old or older) Timolol : Elevated intra-ocular pressure, chronic open-angle glaucoma – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary prevention of cardiovascular disease	Pravastatin : Primary prevention of cardiovascular disease – only adults (18 years old or older) Rosuvastatin : Primary prevention of cardiovascular disease – only adults (18 - 65 years old)
Primary syphilis	Doxycycline : Primary and secondary syphilis – only adults (18 years old or older)
Prinzmetal angina	Amlodipine : Chronic stable angina pectoris, vasospastic angina – only adults (18 years old or older)
Proctitis	Fluocortolone : hemorrhoids, non-infectious proctitis, anal eczema – only adults (18 years old or older)
Proctoscopy	Lidocaine : Bronchoscopy, gastroscopy, colonoscopy, rectoscopy – only adults (18 years old or older)
Productive cough	Guaifenesin : Productive cough – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Progressive relapsing multiple sclerosis	Methylprednisolone : Acute exacerbations of multiple sclerosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Methylprednisolone : Acute exacerbations of multiple sclerosis – only adults (18 years old or older) Ublituximab : Relapsing forms of multiple sclerosis – only adults (18 years old or older)
Prolactinoma	Bromocriptine : Prolactinoma – only adults (18 years old or older) Bromocriptine : Prolactinoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Proliferative diabetic retinopathy	Ranibizumab : Proliferative diabetic retinopathy (PDR) – only adults (18 years old or older)
Prostate-specific antigen monitoring	Piflufolastat ¹⁸F : Detection of prostate-specific membrane antigen positive lesions in patients with prostate cancer – men, only adults (18 years old or older)
Prurigo	Fluocinonide : Prurigo – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prurigo nodularis	Betamethasone : Prurigo nodularis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Clobetasone : Otitis externa, prurigo nodularis, insect bite reactions – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Hydrocortisone : Prurigo nodularis, neurodermatoses, otitis externa, intertrigo, napkin rash – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pruritus ani	Cinchocaine : Hemorrhoids, anal fissure, pruritus ani – only adults (18 years old or older) Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Pruritus of vulva	Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Pseudocroup	Budesonide : Pseudocroup (laryngitis subglottica) – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Psoriasis	Alefacept : Psoriasis – only adults (18 years old or older) Apremilast : Psoriasis, psoriatic arthritis Ciclosporin : Psoriasis – only adults (18 years old or older) Coal tar : Psoriasis of the skin and scalp – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Infliximab : Psoriasis – only adults (18 years old or older) Methotrexate : Psoriasis – only adults (18 years old or older)
Psoriatic arthritis	Abatacept : Psoriatic Arthritis – only adults (18 years old or older) Adalimumab : Ankylosing spondylitis, axial spondyloarthritis, psoriatic arthritis – only adults (18 years old or older) Apremilast : Psoriasis, psoriatic arthritis Certolizumab pegol : Psoriatic arthritis – only adults (18 years old or older) Etanercept : Psoriatic arthritis – only adults (18 years old or older) Golimumab : Psoriatic arthritis – only adults (18 years old or older) Infliximab : Psoriatic arthritis – only adults (18 years old or older) Ixekizumab : Psoriatic arthritis – only adults (18 years old or older) Leflunomide : Psoriatic arthritis – only adults (18 years old or older) Secukinumab : Psoriatic arthritis – only adults (18 years old or older) Tofacitinib : Psoriatic arthritis Ustekinumab : Psoriatic arthritis – only adults (18 years old or older)
Psychomotor agitation	Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only elderly (65 years old or older) Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only adults (18 - 65 years old) Trifluoperazine : Psychoses, mental subnormality, nausea and vomiting – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Psychomotor epilepsy	Primidone : Grand mal and psychomotor (temporal lobe) epilepsy, focal or Jacksonian seizures, myoclonic jerks, akinetic attacks – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Psychosis co-occurrent and due to Parkinson's disease	Clozapine : Psychosis during the course of Parkinson's disease – only adults (18 years old or older)
Psychotic disorder	Pimozide : Psychotic disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older) Sulpiride : Schizophrenia – only adolescents (12 years - 18 years old) , adults (18 years old or older) Zuclopenthixol : Schizophrenia, psychoses – only adults (18 years old or older)
Pulmonary arterial hypertension associated with connective tissue disease	Riociguat : Pulmonary arterial hypertension (PAH) – only adults (18 years old or older)
Pulmonary aspergillosis	Prednisolone : Pulmonary aspergillosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pulmonary edema	Aminophylline : Pulmonary oedema, paroxysmal nocturnal dyspnoea, status asthmaticus, acute bronchospasm – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Furosemide : Pulmonary oedema – only infants (40 days - 1 year old) , children (1 year - 12 years old) Furosemide : Pulmonary oedema – only adults (18 years old or older)
Pulmonary embolism	Dabigatran : Deep vein thrombosis and pulmonary embolism – only adults (18 years old or older) Dabigatran : Recurrent deep vein thrombosis and pulmonary embolism – only adults (18 years old or older) Dalteparin : Venous thromboembolism (VTE), deep vein thrombosis (DVT), pulmonary embolism (PE) – only adults (18 years old or older) Enoxaparin : Deep vein thrombosis (DVT), pulmonary embolism (PE) – only adults (18 years old or older) Heparin : Pulmonary embolism – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Heparin : Pulmonary embolism – only adults (18 years old or older) Nadroparin : Deep venous thrombosis, pulmonary embolism – only adults (18 years old or older) Rivaroxaban : Deep vein thrombosis (DVT), pulmonary embolism (PE) – only adults (18 years old or older)
Pulmonary emphysema	Metaproterenol : Pulmonary emphysema – only adults (18 - 65 years old) Salbutamol : Pulmonary emphysema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Salbutamol : Pulmonary emphysema – only adults (18 years old or older)
Pulmonary hypertensive arterial disease	Ambrisentan : Pulmonary arterial hypertension (PAH) classified as WHO functional class II and III – only adults (18 years old or older) Bosentan : Pulmonary arterial hypertension (PAH) – only adults (18 years old or older) Macitentan : Pulmonary arterial hypertension (PAH) functional class (FC) II to III – only adults (18 years old or older) Selexipag : Pulmonary arterial hypertension (PAH) – only adults (18 years old or older) Sildenafil : Pulmonary arterial hypertension – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) Sildenafil : Pulmonary arterial hypertension classified as WHO functional class II and III – only adults (18 years old or older) Sitaxentan : Pulmonary arterial hypertension (PAH) classified as WHO functional class III – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Sotatercept : Pulmonary arterial hypertension – only adults (18 years old or older)
Pulmonary hypertensive venous disease	Nitric oxide (NO) : Pulmonary hypertension associated with heart surgery – only adults (18 - 65 years old) Nitric oxide (NO) : Pulmonary hypertension associated with heart surgery – only newborns (0 - 40 days old)
Pulmonary lymphangioleiomyomatosis	Sirolimus : Sporadic lymphangioleiomyomatosis – only adults (18 years old or older)
Pulmonary sarcoidosis	Methylprednisolone : Pulmonary sarcoidosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pulmonary tuberculosis	Rifabutin : Pulmonary tuberculosis – only adults (18 years old or older)

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