RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.
This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.
Select a letter from the index list.
Indication | Treatments |
---|---|
Magnesium deficiency | |
Magnetic resonance imaging |
Gadoteridol
: Magnetic Resonance Imaging (MRI)
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Magnetic resonance imaging (MRI) arthrography of metacarpophalangeal joint |
Gadopentetate dimeglumine
: Magnetic resonance imaging arthrography of finger joint
–
only
adults (18 years old or older)
|
Magnetic resonance imaging (MRI) arthrography of metatarsophalangeal joint |
Gadopentetate dimeglumine
: Magnetic resonance imaging arthrography of finger joint
–
only
adults (18 years old or older)
|
Magnetic resonance imaging of brain and brain stem |
Gadoversetamide
: Magnetic resonance imaging (MRI) of the central nervous system (CNS) and liver
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Magnetic resonance imaging of brain and cervical spinal cord |
Gadopentetate dimeglumine
: Brain and spinal cord MRI
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Magnetic resonance imaging of kidney with contrast |
Gadobutrol
: Magnetic resonance imaging (MRI) of liver or kidneys
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
|
Magnetic resonance imaging of liver with contrast |
Gadobenic acid
: Magnetic resonance imaging of liver with contrast
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Gadobutrol
: Magnetic resonance imaging (MRI) of liver or kidneys
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Gadoversetamide
: Magnetic resonance imaging (MRI) of the central nervous system (CNS) and liver
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Gadoxetic acid
: Magnetic resonance imaging of liver with contrast
–
only
adults (18 years old or older)
|
Magnetic resonance imaging of musculoskeletal structures |
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Magnetic resonance imaging of prostate |
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Magnetic resonance imaging of whole body |
Gadobutrol
: Whole body magnetic resonance imaging (MRI)
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
Gadopentetate dimeglumine
: Magnetic resonance imaging of whole body
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Gadoteric acid
: Magnetic resonance imaging (MRI) of whole body
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
|
Maintaining asepsis |
Iodine
: Antisepsis
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Maintenance of general anaesthesia |
Desflurane
: Maintenance of general anaesthesia
–
only
infants (40 days - 1 year old)
, adolescents (12 years - 18 years old)
Ketamine
: Induction of general anesthesia, maintenance of general anesthesia
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Propofol
: Maintenance of anaesthesia
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Rocuronium
: Facilitation of tracheal intubation to general anaesthesia
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
Sevoflurane
: Induction and maintenance of general anaesthesia
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
|
Major depressive disorder |
Quetiapine
: Add-on treatment of major depressive episodes in patients with Major Depressive Disorder (MDD)
–
only
elderly (65 years old or older)
Quetiapine
: Add-on treatment of major depressive episodes in patients with Major Depressive Disorder (MDD)
–
only
adults (18 years old or older)
|
Malaria | |
Male hypogonadism | |
Male pattern alopecia | |
Male sterility | |
Malignant ascites |
Catumaxomab
: Malignant ascites with EpCAM-positive carcinomas
–
only
adults (18 years old or older)
|
Malignant bone pain |
Samarium ¹⁵³Sm lexidronam
: Bone pain in osteoblastic skeletal metastases
–
only
adults (18 years old or older)
|
Malignant epithelial neoplasm of peritoneum |
Mirvetuximab soravtansine
: FRα positive, platinum-resistant high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
|
Malignant epithelial tumor of ovary |
Bevacizumab
: Epithelial ovarian, fallopian tube and primary peritoneal cancer
–
only
adults (18 years old or older)
Bevacizumab
: First recurrence of platinum-sensitive epithelial ovarian, fallopian tube or primary peritoneal cancer
–
only
adults (18 years old or older)
Bevacizumab
: Platinum-resistant recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Carboplatin
: Advanced ovarian carcinoma of epithelial origin
– women,
only
adults (18 years old or older)
Cis-Diaminedichloroplatinum
: Ovary carcinoma
– women,
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Mirvetuximab soravtansine
: FRα positive, platinum-resistant high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Niraparib
: Advanced epithelial high-grade ovarian, fallopian tube or primary peritoneal cancer
–
only
adults (18 years old or older)
Niraparib
: Platinum-sensitive relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Olaparib
: Maintenance treatment of platinum-sensitive relapsed ovarian cancer, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Rucaparib
: Epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer
–
only
adults (18 years old or older)
|
Malignant glioma of brain |
Temozolomide
: Malignant glioma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Malignant glioma of spinal cord |
Temozolomide
: Malignant glioma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Malignant hypertension |
Nicardipine
: Malignant hypertension, hypertensive encephalopathy, dissection of aorta, postoperative hypertension
–
only
elderly (65 years old or older)
Nicardipine
: Malignant hypertension, hypertensive encephalopathy, dissection of aorta, severe pre-eclampsia, postoperative hypertension
–
only
adults (18 - 65 years old)
|
Malignant lymphoma |
Methylprednisolone
: Malignant lymphoma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Prednisolone
: Lymphoma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Malignant lymphoma, lymphocytic, well differentiated | |
Malignant melanoma |
Nivolumab
: Adjuvant treatment of melanoma
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Pembrolizumab
: Stage IIB, IIC or III melanoma
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Malignant melanoma with B-Raf proto-oncogene, serine/threonine kinase V600E mutation |
Encorafenib
: Unresectable or metastatic melanoma with a BRAF V600 mutation
–
only
adults (18 years old or older)
|
Malignant mesothelioma of pleura | |
Malignant neoplasm of cardio-esophageal junction of stomach |
Fluorouracil
: Gastric cancer, cancer of gastroesophageal junction
–
only
adults (18 years old or older)
Nivolumab
: Adjuvant treatment of oesophageal or gastro-oesophageal junction cancer
–
only
adults (18 years old or older)
Nivolumab
: Gastric, gastro-oesophageal junction or oesophageal adenocarcinoma
–
only
adults (18 years old or older)
Trastuzumab deruxtecan
: Advanced HER2-positive gastric or gastroesophageal junction adenocarcinoma
–
only
adults (18 years old or older)
|
Malignant neoplasm of cecum and/or colon and/or rectum |
Encorafenib
: Metastatic colorectal cancer with a BRAF V600E mutation
–
only
adults (18 years old or older)
|
Malignant neoplasm of central nervous system |
Thiotepa
: Malignant neoplasm of central nervous system
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Malignant neoplasm of endometrium of corpus uteri |
Olaparib
: First-line maintenance treatment of MMR-Proficient advanced or recurrent endometrial cancer
–
only
adults (18 years old or older)
|
Malignant neoplasm of skin | |
Malignant tumor of biliary tract |
Pembrolizumab
: First-line treatment of locally advanced unresectable or metastatic biliary tract carcinoma
–
only
adults (18 years old or older)
|
Malignant tumor of breast | |
Malignant tumor of fallopian tube |
Bevacizumab
: Epithelial ovarian, fallopian tube and primary peritoneal cancer
–
only
adults (18 years old or older)
Bevacizumab
: First recurrence of platinum-sensitive epithelial ovarian, fallopian tube or primary peritoneal cancer
–
only
adults (18 years old or older)
Bevacizumab
: Platinum-resistant recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Mirvetuximab soravtansine
: FRα positive, platinum-resistant high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Niraparib
: Advanced epithelial high-grade ovarian, fallopian tube or primary peritoneal cancer
–
only
adults (18 years old or older)
Niraparib
: Platinum-sensitive relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Olaparib
: Maintenance treatment of platinum-sensitive relapsed ovarian cancer, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Rucaparib
: Epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer
–
only
adults (18 years old or older)
|
Malignant tumor of head and neck | |
Malignant tumor of peritoneum |
Bevacizumab
: Epithelial ovarian, fallopian tube and primary peritoneal cancer
–
only
adults (18 years old or older)
Bevacizumab
: First recurrence of platinum-sensitive epithelial ovarian, fallopian tube or primary peritoneal cancer
–
only
adults (18 years old or older)
Bevacizumab
: Platinum-resistant recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
Niraparib
: Advanced epithelial high-grade ovarian, fallopian tube or primary peritoneal cancer
–
only
adults (18 years old or older)
Niraparib
: Platinum-sensitive relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer
–
only
adults (18 years old or older)
|
Malignant tumor of stomach |
Fluorouracil
: Gastric cancer, cancer of gastroesophageal junction
–
only
adults (18 years old or older)
Ramucirumab
: Advanced gastric cancer, gastro-oesophageal junction adenocarcinoma
–
only
adults (18 years old or older)
|
Malignant tumor of thyroid gland |
Selpercatinib
: RET fusion-positive thyroid cancer
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Thyrotropin
: Detection of thyroid remnants and well-differentiated thyroid cancer
–
only
adults (18 years old or older)
|
Malignant tumour |
Ifosfamide
: Malignant neoplastic disease
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Malignant tumour of cervix |
Pembrolizumab
: Persistent, recurrent, or metastatic cervical cancer with PD-L1 with a CPS ≥1
–
only
adults (18 years old or older)
|
Malignant tumour of oesophagus |
Nivolumab
: Adjuvant treatment of oesophageal or gastro-oesophageal junction cancer
–
only
adults (18 years old or older)
|
Malignant tumour of ovary | |
Malignant tumour of pancreas | |
Malignant tumour of prostate | |
Malignant tumour of testis |
Cis-Diaminedichloroplatinum
: Testicular carcinoma
– men,
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Malignant tumour of urinary bladder | |
Mania | |
Manic bipolar I disorder |
Haloperidol
: Moderate to severe manic episodes associated with bipolar I disorder
–
only
elderly (65 years old or older)
Haloperidol
: Moderate to severe manic episodes associated with bipolar I disorder
–
only
adults (18 - 65 years old)
Iloperidone
: Manic or mixed episodes associated with bipolar I disorder
–
only
adults (18 years old or older)
Risperidone
: Moderate to severe manic episodes associated with bipolar disorders
–
only
adults (18 - 65 years old)
Risperidone
: Moderate to severe manic episodes associated with bipolar disorders
–
only
elderly (65 years old or older)
|
Mannosidosis |
Velmanase alfa
: Mild to moderate alpha-mannosidosis
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Mantle cell lymphoma | |
Marginal keratitis | |
Marginal zone lymphoma | |
Maroteaux-Lamy syndrome |
Galsulfase
: Mucopolysaccharidosis VI
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Mast cell leukemia (clinical) |
Midostaurin
: Aggressive systemic mastocytosis, systemic mastocytosis with associated haematological neoplasm, mast cell leukaemia
–
only
adults (18 - 65 years old)
|
Mastoiditis |
Erythromycin
: Ear infection
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
mCNV - myopic choroidal neovascularisation |
Aflibercept
: Visual impairment due to myopic choroidal neovascularisation (myopic CNV)
–
only
adults (18 years old or older)
|
Measurement of renal function |
Desmopressin
: Diagnostic test of the renal concentrating capacity
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Mediastinal (thymic) large B-cell lymphoma |
Axicabtagene ciloleucel
: Primary mediastinal large B-cell lymphoma (PMBCL)
–
only
adults (18 years old or older)
Lisocabtagene maraleucel
: Primary mediastinal large B-cell lymphoma (PMBCL)
–
only
adults (18 years old or older)
|
Medical termination of pregnancy |
Mifepristone
: Medical termination of developing intra-uterine pregnancy
– women,
only
adults (18 - 65 years old)
|
Medullary thyroid carcinoma |
Selpercatinib
: RET-mutant medullary thyroid cancer
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Vandetanib
: Medullary thyroid cancer
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Medulloblastoma |
22-Oxovincaleukoblastine
: Medulloblastoma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Megaloblastic anemia due to folate deficiency |
Calcium folinate
: Megaloblastic anaemia due to folate deficiency
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Folic acid
: Folate-deficient megaloblastic anaemia
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Megaloblastic anemia due to folate deficiency in pregnancy and lactation |
Folic acid
: Megaloblastic anemia due to folate deficiency in pregnancy and lactation
– women,
only
adults (18 - 65 years old)
|
Megaloblastic anemia due to vitamin B>12< deficiency |
Vitamin B12
: Addisonian pernicious anaemia, cobalamin deficiency, megaloblastic anemia due to vitamin B12 deficiency
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Ménière's disease |
Cinnarizine
: Vestibular disorders, Meniere's disease
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Dimenhydrinate
: Nausea, vertigo
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
Dimenhydrinate
: Nausea, vertigo
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Meningeal leukemia |
Methotrexate
: Meningeal leukaemia
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Meningitis | |
Menorrhagia |
Norethisterone
: Dysfunctional uterine bleeding, polymenorrhoea, menorrhagia, dysmenorrhoea, metropathia haemorrhagia
– women,
only
adults (18 - 65 years old)
|
Merkel cell carcinoma |
Retifanlimab
: Metastatic or recurrent locally advanced Merkel cell carcinoma
–
only
adults (18 years old or older)
|
Merkel cell tumour | |
Metabolic acidosis |
Sodium bicarbonate
: Metabolic acidosis
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Metachromatic leukodystrophy, juvenile type |
Atidarsagene autotemcel
: Metachromatic leukodystrophy with reduced arylsulfatase A enzymatic activity
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
|
Metachromatic leukodystrophy, late infantile type |
Atidarsagene autotemcel
: Metachromatic leukodystrophy with reduced arylsulfatase A enzymatic activity
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
|
Metastasis from malignant tumor of breast |
Cyclophosphamide
: Metastatic breast carcinoma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Metastatic basal cell carcinoma |
Cemiplimab
: Locally advanced or metastatic basal cell carcinoma
–
only
adults (18 years old or older)
|
Metastatic cholangiocarcinoma |
Ivosidenib
: Locally advanced or metastatic cholangiocarcinoma with an isocitrate dehydrogenase-1 R132 mutation
–
only
adults (18 years old or older)
|
Metastatic malignant melanoma |
Pembrolizumab
: Advanced (unresectable or metastatic) melanoma
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Metastatic renal cell carcinoma |
Aldesleukin
: Metastatic renal cell carcinoma (metastatic RCC)
–
only
adults (18 years old or older)
|
Methotrexate poisoning |
Calcium folinate
: Calcium folinate rescue in methotrexate therapy
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Glucarpidase
: Reduction of toxic plasma methotrexate concentration
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Metropathia hemorrhagica |
Norethisterone
: Dysfunctional uterine bleeding, polymenorrhoea, menorrhagia, dysmenorrhoea, metropathia haemorrhagia
– women,
only
adults (18 - 65 years old)
|
Microalbuminuric diabetic nephropathy |
Ramipril
: Renal disease in patients with diabetes and microalbuminuria
–
only
adults (18 years old or older)
|
Microglioma | |
Microscopic polyarteritis |
Avacopan
: Granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA)
–
only
adults (18 years old or older)
Rituximab
: Granulomatosis with polyangiitis and microscopic polyangiitis
–
only
adults (18 years old or older)
|
Middle insomnia | |
Migraine |
Flunarizine
: Prophylaxis of migraine
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Flurbiprofen
: Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Galcanezumab
: Migraine
Mefenamic acid
: Migraine
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Paracetamol
: Pain, fever
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Propranolol
: Migraine
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Sumatriptan
: Migraine attacks
–
only
adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
Zolmitriptan
: Treatment of migraine headache with or without aura
–
only
adults (18 - 65 years old)
|
Migraine with aura |
Eletriptan
: Headache phase of migraine attacks with or without aura
–
only
adults (18 - 65 years old)
Rizatriptan
: Headache phase of migraine attacks with or without aura
–
only
adults (18 years old or older)
|
Migraine without aura |
Eletriptan
: Headache phase of migraine attacks with or without aura
–
only
adults (18 - 65 years old)
Rizatriptan
: Headache phase of migraine attacks with or without aura
–
only
adults (18 years old or older)
|
Mild hemophilia A |
Desmopressin
: Mild to moderate haemophilia, von Willebrand's disease
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Mild pain |
Codeine
: Mild to moderate pain
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Ibuprofen
: Mild to moderate pain
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Mild persistent asthma |
Montelukast
: Mild to moderate persistent asthma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Minimal change disease |
Prednisolone
: Minimal change glomerulonephritis
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Mismatch repair deficient colorectal cancer |
Ipilimumab
: Mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) colorectal cancer
–
only
adults (18 years old or older)
Nivolumab
: Mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) colorectal cancer (CRC)
–
only
adults (18 years old or older)
Pembrolizumab
: Colorectal cancer with microsatellite instability high (MSI-H) or mismatch repair deficient (dMMR) cancers
–
only
adults (18 years old or older)
|
Missed abortion |
Oxytocin
: Incomplete abortion, inevitable abortion, missed abortion
– women,
only
adults (18 - 65 years old)
|
Mixed anxiety and depressive disorder |
Alprazolam
: Moderate or severe anxiety, anxiety associated with depression
–
only
elderly (65 years old or older)
Alprazolam
: Moderate or severe anxiety, anxiety associated with depression
–
only
adults (18 - 65 years old)
|
Mixed bipolar I disorder |
Iloperidone
: Manic or mixed episodes associated with bipolar I disorder
–
only
adults (18 years old or older)
|
Mixed collagen vascular disease |
Prednisolone
: Mixed collagen vascular disease
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Mixed hyperlipidaemia |
Atorvastatin
: Primary hypercholesterolaemia, combined hyperlipidaemia
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Bezafibrate
: Severe hypertriglyceridaemia, mixed hyperlipidaemia
–
only
adults (18 years old or older)
Ciprofibrate
: Severe hypertriglyceridaemia, mixed hyperlipidaemia
–
only
adults (18 years old or older)
Fenofibrate
: Severe hypertriglyceridaemia, mixed hyperlipidaemia
–
only
adults (18 years old or older)
Gemfibrozil
: Severe hypertriglyceridaemia, mixed hyperlipidaemia, primary hypercholesterolaemia
–
only
adults (18 years old or older)
|
MMN - Motor neuropathy with multiple conduction block |
Immunoglobulins, normal human, IV
: Multifocal motor neuropathy (MMN)
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Moderate haemophilia B with inhibitor |
Desmopressin
: Mild to moderate haemophilia, von Willebrand's disease
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Moderate haemophilia B without inhibitor |
Desmopressin
: Mild to moderate haemophilia, von Willebrand's disease
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
Etranacogene dezaparvovec
: Severe and moderately severe Haemophilia B without Factor IX inhibitors
–
only
adults (18 years old or older)
|
Moderate hemophilia A |
Desmopressin
: Mild to moderate haemophilia, von Willebrand's disease
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Moderate major depression |
Fluoxetine
: Moderate to severe major depressive episode
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Moderate manic bipolar I disorder |
Asenapine
: Moderate to severe manic episodes associated with bipolar I disorder
–
only
adults (18 years old or older)
Haloperidol
: Moderate to severe manic episodes associated with bipolar I disorder
–
only
elderly (65 years old or older)
Haloperidol
: Moderate to severe manic episodes associated with bipolar I disorder
–
only
adults (18 - 65 years old)
Quetiapine
: Schizophrenia, moderate to severe manic episodes in bipolar disorder
–
only
adults (18 years old or older)
Risperidone
: Moderate to severe manic episodes associated with bipolar disorders
–
only
adults (18 - 65 years old)
Risperidone
: Moderate to severe manic episodes associated with bipolar disorders
–
only
elderly (65 years old or older)
Ziprasidone
: Manic or mixed episodes of moderate severity in bipolar disorder
–
only
adults (18 years old or older)
|
Moderate pain |
Codeine
: Mild to moderate pain
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Ibuprofen
: Mild to moderate pain
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
Nalbuphine
: Moderate to severe pain, postoperative pain
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
Pethidine
: Moderate to severe pain
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
Tramadol
: Moderate to severe pain
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Moderate persistent asthma |
Montelukast
: Mild to moderate persistent asthma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Moderate pulmonary hypertension |
Iloprost
: Primary pulmonary hypertension, classified as NYHA functional class III
–
only
adults (18 years old or older)
|
Molluscum contagiosum infection |
Berdazimer
: Molluscum contagiosum infection
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Molybdenum cofactor deficiency complementation group A |
Fosdenopterin
: Molybdenum cofactor deficiency (MoCD) Type A
–
only
minors (0 - 18 years old)
, adults (18 - 65 years old)
|
Monkeypox |
Tecovirimat
: Smallpox, monkeypox, cowpox
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Mood disorder |
Lithium
: Prophylactic treatment of recurrent affective disorders
–
only
adults (18 years old or older)
|
Motion sickness |
Cinnarizine
: Motion sickness
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Dimenhydrinate
: Nausea, vertigo
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
Dimenhydrinate
: Nausea, vertigo
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Diphenhydramine
: Motion sickness
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Diphenhydramine
: Motion sickness
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Meclozine
: Motion sickness
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Movement disorder | |
MRI arthrography of ankle |
Gadopentetate dimeglumine
: Magnetic resonance imaging arthrography of ankle
–
only
adults (18 years old or older)
|
MRI arthrography of elbow |
Gadopentetate dimeglumine
: Magnetic resonance imaging arthrography of elbow
–
only
adults (18 years old or older)
|
MRI arthrography of hip |
Gadopentetate dimeglumine
: Magnetic resonance imaging arthrography of hip
–
only
adults (18 years old or older)
|
MRI arthrography of knee |
Gadopentetate dimeglumine
: Magnetic resonance imaging arthrography of knee
–
only
adults (18 years old or older)
|
MRI arthrography of shoulder |
Gadopentetate dimeglumine
: Magnetic resonance imaging arthrography of shoulder
–
only
adults (18 years old or older)
|
MRI arthrography of wrist |
Gadopentetate dimeglumine
: Magnetic resonance imaging arthrography of wrist
–
only
adults (18 years old or older)
|
MRI of brain |
Gadobutrol
: Cranial and spinal magnetic resonance imaging (MRI)
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Gadoteric acid
: Magnetic resonance imaging (MRI) of brain
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
|
MRI of breast |
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
MRI of head and spine with contrast |
Gadoversetamide
: Magnetic resonance imaging (MRI) of the central nervous system (CNS) and liver
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
MRI of kidneys |
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
MRI of lungs |
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
MRI of pancreas |
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
MRI of spine |
Gadobutrol
: Cranial and spinal magnetic resonance imaging (MRI)
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
Gadopiclenol
: Magnetic resonance imaging
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Gadoteric acid
: Magnetic resonance imaging (MRI) of spine
–
only
minors (0 - 18 years old)
, adults (18 years old or older)
Gadoversetamide
: Magnetic resonance imaging (MRI) of the central nervous system (CNS) and liver
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Mucocutaneous candidiasis |
Fluconazole
: Mucosal candidiasis
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
|
Mucolytic drug therapy |
Acetylcysteine
: Liquefaction of secretions in bronchitis, emphysema, tracheobronchitis, chronic asthmatic bronchitis
–
only
infants (40 days - 1 year old)
Acetylcysteine
: Liquefaction of secretions in bronchitis, emphysema, tracheobronchitis, chronic asthmatic bronchitis
–
only
children (1 year - 12 years old)
Acetylcysteine
: Liquefaction of secretions in bronchitis, emphysema, tracheobronchitis, chronic asthmatic bronchitis
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Ambroxol
: Mucolytic therapy
–
only
adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Mucopolysaccharidosis, MPS-I |
Laronidase
: Mucopolysaccharidosis I
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Mucopolysaccharidosis, MPS-II |
Idursulfase
: Mucopolysaccharidosis type II
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Mucopolysaccharidosis, MPS-VII | |
Mucormycosis |
Amphotericin B
: Mucormycosis
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Multibacillary leprosy |
Dapsone
: Multibacillary leprosy
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Multidrug resistant tuberculosis |
4-Aminosalicylic acid
: Multi-drug resistant tuberculosis
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
Bedaquiline
: Multidrug-resistant tuberculosis (MDR-TB)
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Delamanid
: Multi-drug resistant tuberculosis (MDR-TB)
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Multiple myeloma (clinical) |
Cyclophosphamide
: Multiple Myeloma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
Idecabtagene vicleucel
: Relapsed and refractory multiple myeloma
–
only
adults (18 years old or older)
Lenalidomide
: Multiple myeloma with at least one prior therapy
–
only
adults (18 years old or older)
Lenalidomide
: Newly diagnosed multiple myeloma - combination treatment with bortezomib and dexamethasone
–
only
adults (18 years old or older)
Lenalidomide
: Newly diagnosed multiple myeloma - combination treatment with dexamethasone
–
only
adults (18 - 65 years old)
Lenalidomide
: Newly diagnosed multiple myeloma - combination treatment with melphalan and prednisone
–
only
adults (18 years old or older)
Lenalidomide
: Newly diagnosed multiple myeloma - maintenance treatment
–
only
adults (18 years old or older)
Prednisolone
: Multiple myeloma
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Multiple sclerosis |
Interferon beta-1b
: Multiple sclerosis
–
only
adolescents (12 years - 18 years old)
, adults (18 - 65 years old)
|
Multiple system atrophy |
Prednisolone
: Shy-Drager syndrome
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Muscle spasticity |
Diazepam
: Upper motor neuronic spasticity
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Musculoskeletal pain | |
Myalgia |
Ibuprofen
: Muscular pain, sprains, strains, sports injuries
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Paracetamol
: Pain, fever
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Myasthenia gravis |
Pyridostigmine
: Myasthenia gravis
–
only
adolescents (12 years - 18 years old)
, adults (18 years old or older)
Zilucoplan
: Myasthenia gravis in patients who are anti-acetylcholine receptor antibody positive
–
only
adults (18 years old or older)
|
Mycobacterium tuberculosis |
4-Aminosalicylic acid
: Multi-drug resistant tuberculosis
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
|
Mycosis |
Amphotericin B
: Severe systemic and/or deep mycoses
–
only
infants (40 days - 1 year old)
, children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Mycosis fungoides (clinical) |
Chlormethine
: Mycosis fungoides-type cutaneous T-cell lymphoma (MF-type CTCL)
–
only
adults (18 years old or older)
Methotrexate
: Mycosis fungoides
–
only
children (1 year - 12 years old)
, adolescents (12 years - 18 years old)
, adults (18 years old or older)
|
Myelodysplastic syndrome (clinical) |
Azacitidine
: Myelodysplastic syndromes, chronic myelomonocytic leukaemia, acute myeloid leukaemia
–
only
adults (18 years old or older)
Imetelstat
: Low- to intermediate-1 risk myelodysplastic syndromes with transfusion-dependent anemia
–
only
adults (18 years old or older)
|
Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia | |
Myelofibrosis | |
Myeloid neoplasm associated with beta-type platelet-derived growth factor receptor gene rearrangement |
Imatinib
: Myelodysplastic/myeloproliferative diseases (MDS/MPD) with platelet-derived growth factor receptor (PDGFR) gene re-arrangements
–
only
adults (18 years old or older)
|
Myeloid/lymphoid neoplasm associated with PDGFRA rearrangement |
Imatinib
: Advanced hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL) with FIP1L1-PDGFRa rearrangement
–
only
adults (18 years old or older)
|
Myelosclerosis with myeloid metaplasia |
Fedratinib
: Primary myelofibrosis, post polycythaemia vera myelofibrosis, post essential thrombocythaemia myelofibrosis
–
only
adults (18 years old or older)
|
Myocardial infarction |
Docosahexaenoic acid
: Secondary prevention after secondary myocardial infarction
–
only
adults (18 years old or older)
|
Myocardial ischemia | |
Myotonia |
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