Indications A-Z

RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.

This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Indications starting with 'C'

Indication Treatments
CA - Carcinoma of breast
22-Oxovincaleukoblastine : Breast carcinoma – only adults (18 years old or older)
Melphalan : Carcinoma of breast – only adults (18 years old or older)
Methotrexate : Breast carcinoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Norethisterone : Disseminated breast carcinoma – only adults (18 years old or older)
Calcium deficiency
Calcium : Calcium deficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Calcium carbonate : Calcium deficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Calcium chloride : Hypocalcaemia, calcium deficiency – only adults (18 years old or older)
Cancer-related anaemia
Epoetin theta : Symptomatic anaemia in non-myeloid malignancies – only adults (18 years old or older)
Candidal balanitis
Clotrimazole : Candidal vulvovaginitis, balanitis
Econazole : Mycotic balanitis – men, only adolescents (12 years - 18 years old) , adults (18 years old or older)
Candidal vulvovaginitis
Clotrimazole : Candidal vulvovaginitis, balanitis
Candidemia
Voriconazole : Candidemia – only children (1 year - 12 years old)
Voriconazole : Candidemia – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Candidiasis of mouth
Chlorhexidine : Gingivitis, oral surgery, aphthous ulceration, oral candidal infections – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Fluconazole : Oropharyngeal candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Miconazole : Candidosis of the oropharynx – only newborns (0 - 40 days old) , infants (40 days - 1 year old)
Miconazole : Candidosis of the oropharynx – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Nystatin : Prophylaxis against oral candidosis – only newborns (0 - 40 days old)
Posaconazole : Oropharyngeal candidiasis – only adults (18 years old or older)
Candidiasis of skin
Econazole : Cutaneous candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Terbinafine : Cutaneous candida – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Candidiasis of the esophagus
Fluconazole : Oesophageal candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Micafungin : Oesophageal candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Candidiasis of vagina
Clotrimazole : Candidal vaginitis
Econazole : Vaginitis due to Candida albicans – women, only adolescents (12 years - 18 years old) , adults (18 years old or older)
Fenticonazole : Vulvovaginal candidiasis – women, only adults (18 years old or older)
Miconazole : Vulvovaginal candidosis – women, only adults (18 years old or older)
Candidiasis of vulva
Fenticonazole : Vulvovaginal candidiasis – women, only adults (18 years old or older)
Candiduria
Fluconazole : Candiduria – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Capillaria philippinensis infection
Albendazole : Capillaria philippinensis – only adults (18 - 65 years old)
Capsulitis
Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older)
Carcinoid syndrome diarrhea
Telotristat : Carcinoid syndrome diarrhoea – only adults (18 years old or older)
Carcinoid tumor
Interferon, alfa-2b : Carcinoid tumor – only adults (18 - 65 years old)
Octreotide : Gastro-entero-pancreatic endocrine tumours – only adults (18 years old or older)
Carcinoma in situ of bladder
BCG vaccine : Adjuvant therapy after TUR of a superficial papillary transitional cell carcinoma of the urinary bladder – only adults (18 years old or older)
BCG vaccine : Primary or concurrent carcinoma-in-situ of the urinary bladder – only adults (18 years old or older)
Epirubicin : Papillary transitional cell carcinoma of the bladder, carcinoma-in-situ of the bladder – only adults (18 years old or older)
Carcinoma of bladder
Epirubicin : Papillary transitional cell carcinoma of the bladder, carcinoma-in-situ of the bladder – only adults (18 years old or older)
Carcinoma of cervix
Topotecan : Carcinoma of cervix – women, only adults (18 years old or older)
Carcinoma of colon
Bevacizumab : Metastatic carcinoma of the colon or rectum (mCRC) – only adults (18 years old or older)
Carcinoma of pancreas
Mitomycin : Advanced pancreatic carcinoma – only adults (18 years old or older)
Carcinoma of prostate
Abarelix : Advanced prostate cancer – men, only adults (18 years old or older)
Buserelin : Advanced hormone dependent prostatic carcinoma – men, only adults (18 years old or older)
Cabazitaxel : Prostate cancer – men, only adults (18 years old or older)
Docetaxel : Prostate cancer – only adults (18 years old or older)
Estradiol : Androgen-dependent carcinoma of the prostate – only adults (18 - 65 years old)
Estramustine : Carcinoma of the prostate – men, only adults (18 years old or older)
Carcinoma of stomach
Mitomycin : Advanced metastatic gastric carcinoma – only adults (18 years old or older)
Carcinoma of urinary bladder, superficial
Mitomycin : Superficial urinary bladder carcinoma – only elderly (65 years old or older)
Cardiac arrest
Epinephrine : Cardiac arrest – only adults (18 years old or older)
Epinephrine : Cardiac arrest – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Sodium bicarbonate : Cardiac arrest – only adults (18 years old or older)
Cardiac edema
Acetazolamide : Congestive heart failure oedema, drug induced oedema – only adults (18 years old or older)
Bumetanide : Oedema – only adults (18 years old or older)
Furosemide : Oedema – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Furosemide : Oedema – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Hydrochlorothiazide : Edema of heart failure – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Cardiac resuscitation
Calcium gluconate : Cardiac resuscitation – only adults (18 years old or older)
Cardiac transplant rejection
Tacrolimus : Prophylaxis of transplant rejection in cardiac allograft recipients – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Tacrolimus : Prophylaxis of transplant rejection in cardiac allograft recipients – only adults (18 years old or older)
Cardiogenic shock
Dobutamine : Cardiac decompensation, disturbed ventricular function – only minors (0 - 18 years old)
Dobutamine : Cardiac decompensation, disturbed ventricular function – only adults (18 years old or older)
Cardiopulmonary resuscitation
Atropine : Cardiopulmonary resuscitation – only adults (18 years old or older)
Calcium chloride : Cardio-pulmonary resuscitation – only adults (18 years old or older)
Epinephrine : Cardiopulmonary resuscitation – only adults (18 years old or older)
Cardiovascular disorder
Simvastatin : Cardiovascular prevention – only adults (18 years old or older)
Cardiovascular event
Atorvastatin : Cardiovascular event – only adults (18 years old or older)
Ezetimibe : Cardiovascular events – only adults (18 years old or older)
Cardiovascular event risk
Atorvastatin : Cardiovascular event – only adults (18 years old or older)
Ezetimibe : Cardiovascular events – only adults (18 years old or older)
Cardiovascular syphilis
Tetracycline : Syphilis of more than one year's duration – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Carditis due to rheumatic fever
Methylprednisolone : Carditis due to rheumatic fever – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Carnitine deficiency
L-carnitine : Primary and secondary carnitine deficiency – only minors (0 - 18 years old) , adults (18 years old or older)
Carpal tunnel syndrome
Dexamethasone : Carpal tunnel syndrome – only adults (18 years old or older)
Cataplexy
Clomipramine : Cataplexy associated with narcolepsy – only adults (18 years old or older)
Cataplexy and narcolepsy
Clomipramine : Cataplexy associated with narcolepsy – only adults (18 years old or older)
CDKL5 (cyclin-dependent kinase-like 5) deficiency
Ganaxolone : Epileptic seizures associated with cyclindependent kinase-like 5 (CDKL5) deficiency disorder – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Central precocious puberty
Leuprorelin : Central precocious puberty – only children (1 year - 12 years old)
Triptorelin : Central precocious puberty – only children (1 year - 12 years old)
Central retinal vein occlusion with macular edema
Dexamethasone : Central retinal vein occlusion with macular edema – only adults (18 years old or older)
Cerebral atherosclerosis
Meclofenoxate : Cerebral atherosclerosis – only adults (18 years old or older)
Cerebral cortex myoclonus
Piracetam : Cortical myoclonus – only adults (18 years old or older)
Cerebral edema
Dexamethasone : Cerebral edema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Glucose : Cerebral oedema – only minors (0 - 18 years old) , adults (18 years old or older)
Mannitol : Raised intracranial pressure, cerebral oedema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Cerebral palsy
Diazepam : Cerebral palsy – only elderly (65 years old or older)
Diazepam : Cerebral palsy – only adults (18 - 65 years old)
Cervical arthritis
Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older)
Cervical thyroid remnant
Thyrotropin : Detection of thyroid remnants and well-differentiated thyroid cancer – only adults (18 years old or older)
Cesarean section
Oxytocin : Caesarean section – women, only adults (18 - 65 years old)
Chancroid
Doxycycline : Chancroid, granuloma inguinale, lymphogranuloma venereum – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Cheloid of skin
Dexamethasone : Keloid scar – only adults (18 years old or older)
Chemical pleurodesis
Lidocaine : Chemical pleurodesis – only adults (18 years old or older)
Chemotherapy-induced nausea and vomiting
Aprepitant : Prevention of nausea and vomiting associated with chemotherapy – only adolescents (12 years - 18 years old)
Aprepitant : Prevention of nausea and vomiting associated with chemotherapy – only adults (18 years old or older)
Fosaprepitant : Prevention of nausea and vomiting associated with chemotherapy – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Fosaprepitant : Prevention of nausea and vomiting associated with chemotherapy – only adults (18 years old or older)
Granisetron : Nausea and vomiting associated with chemotherapy and radiotherapy – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Granisetron : Nausea and vomiting associated with chemotherapy and radiotherapy – only adults (18 years old or older)
Granisetron : Prevention of nausea and vomiting associated with chemotherapy and radiotherapy – only adults (18 years old or older)
Ondansetron : Chemotherapy induced nausea and vomiting (CINV) – only minors (0 - 18 years old)
Ondansetron : Chemotherapy induced nausea and vomiting (CINV) – only adults (18 years old or older)
Palonosetron : Prevention of nausea and vomiting associated with chemotherapy – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Chlamydia trachomatis infection of anus and rectum
Doxycycline : Uncomplicated urethral, endocervical or rectal infection caused by Chlamydia trachomatis – only adults (18 years old or older)
Tetracycline : Uncomplicated urethral, endocervical or rectal infections caused by Chlamydia trachomatis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chlamydia trachomatis urethritis
Doxycycline : Uncomplicated urethral, endocervical or rectal infection caused by Chlamydia trachomatis – only adults (18 years old or older)
Tetracycline : Uncomplicated urethral, endocervical or rectal infections caused by Chlamydia trachomatis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chlamydial infection
Spiramycin : Chlamydial infection – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Spiramycin : Chlamydial infection – only adults (18 - 65 years old)
Cholangiocarcinoma of biliary tract
Futibatinib : Cholangiocarcinoma with a fibroblast growth factor receptor 2 fusion or rearrangement – only adults (18 years old or older)
Pemigatinib : Cholangiocarcinoma with a fibroblast growth factor receptor 2 (FGFR2) fusion or rearrangement – only adults (18 years old or older)
Cholera
Ciprofloxacin : Cholera – only adults (18 years old or older)
Doxycycline : Cholera – only children (1 year - 12 years old)
Doxycycline : Cholera – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Cholestanol storage disease
Chenodeoxycholic acid : Sterol 27-hydroxylase deficiency, cerebrotendinous xanthomatosis (CTX) – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Chenodeoxycholic acid : Sterol 27-hydroxylase deficiency, cerebrotendinous xanthomatosis (CTX) – only adults (18 - 65 years old)
Cholesterolosis of gallbladder
Ursodeoxycholic acid : X-ray radiolucent (X-ray negative) gallstones – only adults (18 years old or older)
Cholinergic crisis
Atropine : Cholinergic crisis – only adults (18 years old or older)
Choriocarcinoma
Methotrexate : Choriocarcinoma, trophoblastic diseases – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Choroidal retinal neovascularization
Verteporfin : Subfoveal choroidal neovascularisation (CNV) – only adults (18 years old or older)
Chronic active hepatitis
Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic anal fissure
Glyceryl trinitrate : Chronic anal fissure – only adults (18 years old or older)
Chronic arthritis of juvenile onset
Methylprednisolone : Juvenile chronic arthritis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic atrial fibrillation
Digoxin : Chronic atrial fibrillation – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Digoxin : Chronic atrial fibrillation – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic atrial flutter
Digoxin : Chronic atrial flutter – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Digoxin : Chronic atrial flutter – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic atrophic candidosis
Fluconazole : Chronic atrophic candidosis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic bronchitis
Metaproterenol : Chronic bronchitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Salbutamol : Chronic bronchitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Salbutamol : Chronic bronchitis – only adults (18 years old or older)
Chronic congestive heart failure
Bisoprolol : Stable chronic heart failure with reduced systolic ventricular function – only adults (18 years old or older)
Chronic constipation
Prucalopride : Chronic constipation – women, only adults (18 - 65 years old)
Prucalopride : Chronic constipation – women, only elderly (65 years old or older)
Chronic cough
Gefapixant : Chronic cough – only adults (18 years old or older)
Chronic eczema of external auditory canal
Fluocinolone : Chronic eczematous external otitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic gastritis
Sucralfate : Duodenal ulcer, chronic gastritis, peptic esophagitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic generalized exfoliative dermatitis
Betamethasone : Generalised erythroderma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic granulomatous disease
Interferon gamma-1b : Chronic granulomatous disease (CGD) – only adults (18 - 65 years old)
Chronic hand eczema
Alitretinoin : Severe chronic hand eczema – only adults (18 - 65 years old)
Chronic heart failure
Captopril : Chronic heart failure – only adults (18 years old or older)
Carvedilol : Mild-to-severe chronic heart failure of ischemic or cardiomyopathic origin – only adults (18 years old or older)
Cilazapril : Chronic heart failure – only adults (18 - 65 years old)
Dapagliflozin : Symptomatic chronic heart failure – only adults (18 years old or older)
Empagliflozin : Chronic heart failure – only adults (18 years old or older)
Ivabradine : Chronic heart failure NYHA II to IV class with systolic dysfunction – only adults (18 years old or older)
Losartan : Chronic heart failure – only adults (18 years old or older)
Nebivolol : Chronic heart failure (CHF) – only adults (18 years old or older)
Vericiguat : Chronic heart failure – only adults (18 years old or older)
Chronic hepatitis C caused by Hepatitis C virus genotype 1
Peginterferon alpha-2b : Chronic hepatitis C (CHC) genotype 1 – only adults (18 - 65 years old)
Chronic idiopathic neutropenia
Filgrastim : Cyclic neutropenia, idiopathic neutropenia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic idiopathic thrombocytopenic purpura
22-Oxovincaleukoblastine : Idiopathic thrombocytopenic purpura (ITP) – only adults (18 years old or older)
Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylprednisolone : Idiopathic thrombocytopenic purpura – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Idiopathic thrombocytopenic purpura – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Romiplostim : Chronic immune (idiopathic) thrombocytopenic purpura (ITP) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic idiopathic urticaria
Cetirizine : Seasonal and perennial allergic rhinitis, chronic idiopathic urticaria – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Ebastine : Idiopathic chronic urticaria – only adults (18 years old or older)
Loratadine : Chronic idiopathic urticaria – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic inflammatory demyelinating polyradiculoneuropathy
Human normal immunoglobulin G : Immunomodulatory therapy in CIDP – only minors (0 - 18 years old) , adults (18 - 65 years old)
Immunoglobulins, normal human, IV : Chronic inflammatory demyelinating polyneuropathy (CIDP) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic interstitial cystitis
Pentosan polysulfate : Bladder pain syndrome – only adults (18 - 65 years old)
Chronic kidney disease
Dapagliflozin : Chronic kidney disease – only adults (18 years old or older)
Empagliflozin : Chronic kidney disease – only adults (18 years old or older)
Chronic kidney disease stage 3
Finerenone : Chronic kidney disease (stage 3 and 4 with albuminuria) associated with type 2 diabetes – only adults (18 years old or older)
Chronic kidney disease stage 4
Finerenone : Chronic kidney disease (stage 3 and 4 with albuminuria) associated with type 2 diabetes – only adults (18 years old or older)
Sucroferric oxyhydroxide : Chronic kidney disease on dialysis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Chronic kidney disease stage 5
Sucroferric oxyhydroxide : Chronic kidney disease on dialysis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Chronic lung disease
Theophylline : Acute exacerbations of the symptoms and reversible airflow obstruction associated with asthma and other chronic lung diseases – only minors (0 - 18 years old) , adults (18 years old or older)
Chronic lymphoid leukemia
22-Oxovincaleukoblastine : Acute lymphocytic leukaemia, chronic lymphocytic leukaemia, acute myelogenous leukaemia, chronic myelogenous leukaemia – only adults (18 years old or older)
Acalabrutinib : Chronic lymphocytic leukaemia – only adults (18 years old or older)
Bendamustine : Chronic lymphocytic leukaemia – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chlorambucil : Chronic lymphocytic leukaemia – only adults (18 years old or older)
Fludarabine : B-cell chronic lymphocytic leukaemia (CLL) – only adults (18 years old or older)
Ibrutinib : Chronic lymphocytic leukaemia (CLL) – only adults (18 years old or older)
Idelalisib : Chronic lymphoid leukemia – only adults (18 years old or older)
Ofatumumab : Chronic lymphocytic leukaemia (CLL) – only adults (18 years old or older)
Rituximab : Chronic lymphocytic leukaemia – only adults (18 years old or older)
Venetoclax : Chronic lymphocytic leukaemia (CLL) – only adults (18 years old or older)
Chronic mucocutaneous candidiasis
Fluconazole : Chronic mucocutaneous candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic myeloid leukemia
22-Oxovincaleukoblastine : Acute lymphocytic leukaemia, chronic lymphocytic leukaemia, acute myelogenous leukaemia, chronic myelogenous leukaemia – only adults (18 years old or older)
Busulfan : Chronic myeloid leukaemia – only adults (18 - 65 years old)
Interferon, alfa-2b : Chronic myelogenous leukaemia – only adults (18 - 65 years old)
Ponatinib : Chronic myeloid leukaemia (CML) – only adults (18 years old or older)
Chronic myelomonocytic leukemia, Type II
Azacitidine : Myelodysplastic syndromes, chronic myelomonocytic leukaemia, acute myeloid leukaemia – only adults (18 years old or older)
Chronic non-neuropathic Gaucher's disease
Eliglustat : Gaucher disease type 1 (GD1) – only adults (18 years old or older)
Imiglucerase : Non-neuronopathic (Type 1) Gaucher disease, chronic neuronopathic (Type 3) Gaucher disease – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Miglustat : Gaucher disease type 1 – only adults (18 - 65 years old)
Velaglucerase alfa : Gaucher disease type 1 – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic obstructive lung disease
Aclidinium : Chronic obstructive pulmonary disease – only adults (18 years old or older)
Arformoterol : Bronchoconstriction in patients with chronic obstructive pulmonary disease – only adults (18 years old or older)
Budesonide : Chronic obstructive pulmonary disease – only adults (18 years old or older)
Eformoterol : Chronic obstructive lung disease – only adults (18 years old or older)
Glycopyrronium : Chronic obstructive pulmonary disease – only adults (18 years old or older)
Indacaterol : Chronic obstructive pulmonary disease (COPD) – only adults (18 years old or older)
Ipratropium : Bronchospasm, chronic obstructive pulmonary disease (COPD), asthma, bronchitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Olodaterol : Chronic obstructive pulmonary disease – only adults (18 years old or older)
Salmeterol : Chronic obstructive pulmonary disease (COPD) – only adults (18 years old or older)
Tiotropium : Chronic obstructive pulmonary disease – only adults (18 years old or older)
Umeclidinium : Chronic obstructive pulmonary disease – only adults (18 years old or older)
Vilanterol : Chronic obstructive pulmonary disease (COPD) – only adults (18 years old or older)
Chronic pain
Ethanol : Severe and chronic pain – only adults (18 years old or older)
Fentanyl : Severe chronic pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Fentanyl : Severe chronic pain – only adults (18 years old or older)
Oxycodone : Severe pain which requires long-term opioid treatment – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Ziconotide : Severe, chronic pain – only adults (18 years old or older)
Chronic paranoid psychosis
Zuclopenthixol : Chronic schizophrenia and other chronic psychoses – only adults (18 years old or older)
Chronic schizophrenia
Levosulpiride : Chronic schizophrenia – only adults (18 years old or older)
Zuclopenthixol : Chronic schizophrenia and other chronic psychoses – only adults (18 years old or older)
Chronic systolic heart failure
Bisoprolol : Stable chronic heart failure with reduced systolic ventricular function – only adults (18 years old or older)
Digoxin : Chronic systolic heart failure – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Digoxin : Chronic systolic heart failure – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic trophic ulcer of lower limb
Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Chronic type B viral hepatitis
Adefovir dipivoxil : Chronic hepatitis B – only adults (18 - 65 years old)
Entecavir : Chronic hepatitis B – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Entecavir : Chronic hepatitis B – only adults (18 years old or older)
Interferon, alfa-2b : Chronic hepatitis B – only adults (18 - 65 years old)
Peginterferon alpha-2a : Chronic hepatitis B – only adults (18 years old or older)
Telbivudine : Chronic hepatitis B – only adults (18 years old or older)
Tenofovir alafenamide : Chronic hepatitis B – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic type C viral hepatitis
Dasabuvir : Chronic hepatitis C – only adults (18 years old or older)
Interferon, alfa-2b : Chronic hepatitis C – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Interferon, alfa-2b : Chronic hepatitis C – only adults (18 - 65 years old)
Peginterferon alpha-2a : Chronic hepatitis C (CHC) – only adults (18 years old or older)
Peginterferon alpha-2b : Chronic hepatitis C – only children (1 year - 12 years old)
Ribavirin : Chronic hepatitis C (CHC) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Ribavirin : Chronic hepatitis C (CHC) – only adults (18 years old or older)
Sofosbuvir : Chronic hepatitis C (CHC) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic ulcer of skin
Collagenase : Chronic dermal ulcers, burned areas – only adults (18 years old or older)
Chronic urticaria
Omalizumab : Chronic spontaneous urticaria (CSU) – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Chronic viral hepatitis D
Bulevirtide : Chronic hepatitis delta virus (HDV) infection – only adults (18 years old or older)
Chylothorax
Octreotide : Chylothorax – only adults (18 years old or older)
Circadian rhythm sleep disorder of shift work type
Promethazine : Temporary disturbances of sleep pattern – only adults (18 years old or older)
Cirrhosis of liver
Spironolactone : Hepatic cirrhosis – only adults (18 years old or older)
Classical Hodgkin lymphoma
Nivolumab : Classical Hodgkin Lymphoma (cHL) – only adults (18 years old or older)
Classical phenylketonuria
Sapropterin : Hyperphenylalaninaemia (HPA) in phenylketonuria (PKU) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Clinical diabetic nephropathy
Captopril : Type I diabetic nephropathy – only elderly (65 years old or older)
Captopril : Type I diabetic nephropathy – only adults (18 - 65 years old)
Clostridium difficile
Vancomycin : Clostridium difficile infection (CDI) – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Vancomycin : Clostridium difficile infection (CDI) – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Clostridium difficile infection
Fidaxomicin : Clostridioides difficile infection (CDI) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Fidaxomicin : Clostridioides difficile infection (CDI) – only adults (18 years old or older)
Teicoplanin : Clostridium difficile infection – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Vancomycin : Clostridium difficile infection (CDI) – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Vancomycin : Clostridium difficile infection (CDI) – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Cluster headache
Sumatriptan : Cluster headache – only adults (18 - 65 years old)
Coccidioidomycosis
Fluconazole : Coccidioidomycosis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Coeliac disease
Prednisolone : Celiac syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Cold autoimmune haemolytic anaemia
Sutimlimab : Haemolytic anaemia in patients with cold agglutinin disease (CAD) – only adults (18 years old or older)
Colicky pain
Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only children (1 year - 12 years old)
Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Colitis gravis
Adalimumab : Ulcerative colitis – only adults (18 years old or older)
Beclometasone : Ulcerative colitis – only adults (18 - 65 years old)
Budesonide : Ulcerative colitis – only adults (18 years old or older)
Dexamethasone : Ulcerative colitis – only adults (18 years old or older)
Filgotinib : Ulcerative colitis – only adults (18 years old or older)
Golimumab : Ulcerative colitis – only adults (18 years old or older)
Infliximab : Ulcerative colitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Infliximab : Ulcerative colitis – only adults (18 years old or older)
Mesalazine : Mild to moderate active ulcerative colitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylcellulose : Diverticular disease, ulcerative colitis – only adults (18 years old or older)
Methylprednisolone : Ulcerative colitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Methylprednisolone : Ulcerative colitis – only adults (18 years old or older)
Mirikizumab : Moderately to severely active ulcerative colitis – only adults (18 years old or older)
Prednisolone : Ulcerative colitis – only adults (18 years old or older)
Sulfasalazine : Ulcerative colitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Tofacitinib : Ulcerative colitis
Ustekinumab : Ulcerative colitis – only adults (18 years old or older)
Vedolizumab : Ulcerative colitis – only adults (18 years old or older)
Collagenous colitis
Budesonide : Collagenous colitis – only adults (18 years old or older)
Colonoscopy
Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only children (1 year - 12 years old)
Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Glucagon : Motility inhibition of the gastrointestinal tract – only adults (18 years old or older)
Lidocaine : Bronchoscopy, gastroscopy, colonoscopy, rectoscopy – only adults (18 years old or older)
Colorectal cancer
Aflibercept : Metastatic colorectal cancer (MCRC) – only adults (18 years old or older)
Capecitabine : Colorectal cancer – only adults (18 years old or older)
Fluorouracil : Colorectal cancer – only adults (18 years old or older)
Irinotecan : Colorectal cancer – only adults (18 years old or older)
Oxaliplatin : Colorectal cancer – only adults (18 years old or older)
Panitumumab : Wild-type RAS metastatic colorectal cancer (mCRC) – only adults (18 years old or older)
Ramucirumab : Metastatic colorectal cancer (mCRC) – only adults (18 years old or older)
Regorafenib : Colorectal cancer (CRC) – only adults (18 years old or older)
Colostomy present
Methylcellulose : Colostomy, ileostomy, diarrhoea – only adults (18 years old or older)
Complex regional pain syndrome
Calcitonin : Algodystrophy – only adults (18 years old or older)
Computed tomography of whole body with contrast
Iodixanol : CT of the body – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Computerised axial tomography of brain with radiopaque contrast
Iodixanol : Computerized axial tomography of brain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Computerized axial tomography
Iopromide : Computerized axial tomography – only adults (18 - 65 years old)
Computerized axial tomography of brain
Iopromide : Computerized axial tomography of brain – only adults (18 - 65 years old)
Conduct disorder, solitary aggressive type
Risperidone : Persistent aggression in conduct disorder – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Congenital adrenal hyperplasia
Hydrocortisone : Congenital adrenal hyperplasia – only children (1 year - 12 years old)
Methylprednisolone : Congenital adrenal hyperplasia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Congenital adrenal hyperplasia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Congenital hypofibrinogenemia
Human fibrinogen : Congenital hypofibrinogenaemia, afibrinogenaemia with bleeding tendency – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Congenital hypothyroidism
Levothyroxine : Congenital hypothyroidism – only newborns (0 - 40 days old) , infants (40 days - 1 year old)
Congenital neutropenia
Filgrastim : Congenital neutropenia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Congestion of nasal sinus
Ephedrine : Nasal congestion – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Oxymetazoline : Nasal congestion – only children (1 year - 12 years old)
Oxymetazoline : Nasal congestion – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Phenylephrine : Nasal congestion – only adults (18 - 65 years old)
Pseudoephedrine : Nasal congestion, sinus congestion – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Xylometazoline : Nasal congestion – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Congestive heart failure
Amiloride : Congestive heart failure – only adults (18 - 65 years old)
Glyceryl trinitrate : Unresponsive congestive heart failure – only adults (18 years old or older)
Isosorbide dinitrate : Severe acute or chronic congestive cardiac failure – only adults (18 years old or older)
Isosorbide mononitrate : Congestive heart failure – only adults (18 years old or older)
Milrinone : Severe congestive heart failure – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Milrinone : Severe congestive heart failure – only adults (18 years old or older)
Quinapril : Congestive heart failure – only elderly (65 years old or older)
Quinapril : Congestive heart failure – only adults (18 - 65 years old)
Spironolactone : Congestive heart failure – only adults (18 years old or older)
Conjunctival xerosis
Hypromellose : Dehydration of the cornea and conjunctiva – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Conjunctivitis
Ketotifen : Allergic conditions – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Conscious sedation
Dexmedetomidine : Procedural/awake sedation – only adults (18 years old or older)
Constipation
Glycerol : Constipation – only infants (40 days - 1 year old)
Glycerol : Constipation – only children (1 year - 12 years old)
Glycerol : Constipation – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Lactitol : Constipation – only adults (18 years old or older)
Lactitol : Constipation – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Lactulose : Constipation – only minors (0 - 18 years old) , adults (18 years old or older)
Magnesium hydroxide : Constipation – only children (1 year - 12 years old)
Magnesium hydroxide : Constipation – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylcellulose : Constipation – only adults (18 years old or older)
Methylnaltrexone : Opioid-induced constipation – only adults (18 years old or older)
Naldemedine : Opioid-induced constipation (OIC) – only adults (18 years old or older)
Naloxegol : Opioid-induced constipation (OIC) – only adults (18 years old or older)
Sennosides : Constipation – only children (1 year - 12 years old)
Sennosides : Constipation – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Sodium picosulfate : Constipation – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Sodium picosulfate : Constipation – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Constipation predominant irritable bowel syndrome
Linaclotide : Moderate to severe irritable bowel syndrome with constipation (IBS-C) – only adults (18 years old or older)
Contact dermatitis
Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Fluocinonide : Contact dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Hydrocortisone : Irritant dermatitis, contact allergic dermatitis, insect bite reactions, mild to moderate eczema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Contraception care
Desogestrel : Contraception – women, only adults (18 - 65 years old)
Contrast echocardiography
Perflutren : Contrast echocardiography – only adults (18 years old or older)
Sulfur hexafluoride : Contrast echocardiography – only adults (18 years old or older)
Controlled ovarian stimulation
Cetrorelix : Prevention of premature ovulation – women, only adults (18 - 65 years old)
Choriogonadotropin alpha : Follicular maturation and luteinisation – women, only adults (18 - 65 years old)
Clomifene : Ovulatory dysfunction, ovulation induction – women, only adults (18 - 65 years old)
Corifollitropin alfa : Controlled Ovarian Stimulation (COS) – women, only adults (18 - 65 years old)
Follitropin alfa : Stimulation of multifollicular development – women, only adults (18 - 65 years old)
Follitropin beta : Controlled ovarian hyperstimulation – women, only adults (18 - 65 years old)
Follitropin delta : Controlled ovarian stimulation – women, only adults (18 - 65 years old)
Urofollitropin : Controlled ovarian hyperstimulation – women, only adults (18 - 65 years old)
Contusion
Diethylamine salicylate : Lumbago, fibrositis, sciatica, bruises, strains – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Ketoprofen : Painful musculoskeletal conditions caused by trauma, pain of non serious arthritis – only adults (18 years old or older)
Corneal stromal oedema
Dexamethasone : Corneal stromal edema – only adults (18 years old or older)
Coronary angiography
Iodixanol : Selective coronary arteriography – only adults (18 years old or older)
Iopromide : Coronary angiography – only adults (18 - 65 years old)
Regadenoson : Measurement of fractional flow reserve (FFR) – only adults (18 years old or older)
Coronary atherosclerosis
Evolocumab : Established atherosclerotic cardiovascular disease – only adults (18 years old or older)
Cough
Glycerol : Cough, soreness of the throat – only children (1 year - 12 years old)
Glycerol : Cough, soreness of the throat – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Cowpox
Tecovirimat : Smallpox, monkeypox, cowpox – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Critical lower limb ischaemia
Iloprost : Severe chronic ischaemia of lower limbs – only adults (18 - 65 years old)
Crohn's disease
Adalimumab : Crohn's disease – only adults (18 years old or older)
Adalimumab : Paediatric Crohn's disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Budesonide : Crohn's disease – only adults (18 years old or older)
Dexamethasone : Crohn's disease – only adults (18 years old or older)
Infliximab : Crohn’s disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Infliximab : Crohn’s disease – only adults (18 years old or older)
Mesalazine : Crohn's disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylprednisolone : Crohn's disease – only infants (40 days - 1 year old) , adolescents (12 years - 18 years old)
Methylprednisolone : Crohn's disease – only adults (18 years old or older)
Prednisolone : Crohn's disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Prednisolone : Crohn's disease – only adults (18 years old or older)
Sulfasalazine : Crohn's disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Ustekinumab : Crohn's disease – only adults (18 years old or older)
Vedolizumab : Crohn's disease – only adults (18 years old or older)
Crow's feet
Botulinum toxin type A : Crow’s feet lines seen at maximum smile – only adults (18 - 65 years old)
CRS - cytokine release syndrome
Tocilizumab : Cytokine Release Syndrome (CRS) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Cryopyrin associated periodic syndrome
Anakinra : Cryopyrin-Associated Periodic Syndromes (CAPS) – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Canacinumab : Cryopyrin associated periodic syndromes (CAPS) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Rilonacept : Cryopyrin-Associated Periodic Syndromes (CAPS) – only adolescents (12 years - 18 years old)
Rilonacept : Cryopyrin-Associated Periodic Syndromes (CAPS) – only adults (18 years old or older)
Cryptococcal meningitis
Fluconazole : Cryptococcal meningitis – only newborns (0 - 40 days old)
Fluconazole : Cryptococcal meningitis – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Fluconazole : Cryptococcal meningitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Cryptosporidiasis
Spiramycin : Cryptosporidiosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Spiramycin : Cryptosporidiosis – only adults (18 - 65 years old)
Cyclical neutropaenia
Filgrastim : Cyclic neutropenia, idiopathic neutropenia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Cycloplegic refraction
Cyclopentolate : Diagnostic purposes for fundoscopy and cycloplegic refraction – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Tropicamide : Cycloplegic refraction – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Cystic acne
Dexamethasone : Cystic acne – only adults (18 years old or older)
Cystic fibrosis
Dornase alfa : Cystic fibrosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Ivacaftor : Cystic fibrosis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Mannitol : Cystic fibrosis (CF) – only adults (18 - 65 years old)
Cysticercosis of central nervous system
Albendazole : Neurocysticercosis (NCC) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Albendazole : Neurocysticercosis (NCC) – only adults (18 - 65 years old)
Cystinosis
Mercaptamine : Cystinosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Cystitis
Serrapeptase : Cystitis – only adults (18 years old or older)
Cytomegalovirus infection
Maribavir : Cytomegalovirus (CMV) infection and/or disease – only adults (18 years old or older)

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